Results 51 to 60 of about 10,346 (145)

Serum metabolite profiling reveals metabolic characteristics of sepsis patients using LC/MS-based metabolic profiles: a cross-sectional study

open access: yesBMC Medical Genomics, 2023
Background Individuals with sepsis exhibited a higher likelihood of benefiting from early initiation of specialized treatment to enhance the prognosis of the condition. The objective of this study is to identify potential biomarkers of sepsis by means of
Jinliang Peng   +3 more
doaj   +1 more source

Expression of cell-surface activation markers on human CD15+ cells after selected non esterified fatty acid supplementations

open access: yesLipids in Health and Disease
Background Cell surface marker (CD) expressions and membrane lipid changes characterise circulating neutrophil transmigration into inflammation sites. Specific CD expressions mandate neutrophil activation.
A.N. Hunt   +5 more
doaj   +1 more source

Lipid responses to perfluorooctane sulfonate exposure for multiple rat organs

open access: yesEcotoxicology and Environmental Safety
Perfluorooctane sulfonate (PFOS) is a persistent chemical that has long been a threat to human health. However, the molecular effects of PFOS on various organs are not well studied.
Tzu-Hsin Yen   +4 more
doaj   +1 more source

Aggregation behaviour of a single-chain, phenylene-modified bolalipid and its miscibility with classical phospholipids

open access: yesBeilstein Journal of Organic Chemistry, 2017
In the present work, we describe the synthesis of a single-chain, phenylene-modified bolalipid with two phosphocholine headgroups, PC-C18pPhC18-PC, using a Sonogashira cross-coupling reaction as a key step.
Simon Drescher   +4 more
doaj   +1 more source

Synthesis of the diacetylenic phospholipids 1,2-(10',12'-heptadecadiynoyl)-sn-glycero-3-phophatidylcholine and 1,2-(4',6'-tricosadiynoyl)-sn-glycero-3-phophatidylcholine

open access: yesJournal of the Brazilian Chemical Society, 2001
Diacetylenic phosphatidylcholines are synthetic compounds analogous to natural phospholipids. These molecules can be hydrated to form bilayered aggregates known as liposomes in a manner similar to natural phosphatidylcholines.
Hennies Paulo T.   +2 more
doaj  

Targeted metabolomic profiling of cerebrospinal fluid from patients with progressive multifocal leukoencephalopathy.

open access: yesPLoS ONE, 2020
Progressive multifocal leukoencephalopathy (PML), caused by JC polyomavirus, is a demyelinating disease of the central nervous system that primarily affects oligodendrocytes. It can cause significant morbidity and mortality. An early diagnosis is of high
Yi Luo   +7 more
doaj   +1 more source

Topologies, structures and parameter files for lipid simulations in GROMACS with the OPLS-aa force field: DPPC, POPC, DOPC, PEPC, and cholesterol

open access: yesData in Brief, 2015
In this data article we provide topologies and force field parameters files for molecular dynamics simulations of lipids in the OPLS-aa force field using the GROMACS package.
Waldemar Kulig   +2 more
doaj   +1 more source

Temporal changes in plasma and milk lipids in response to an esophageal bolus of rumen-protected fish oil in lactating Holstein dairy cows

open access: yesAnimal
Feeding very-long-chain omega-3 (VLC n-3) fatty acids (FA), which are found in fish oil, may have beneficial effects on health, fertility, and milk production in the dairy cow.
J.E. Rico   +6 more
doaj   +1 more source

Genetic causality of lipidomic and immune cell profiles in ischemic stroke

open access: yesFrontiers in Neurology
BackgroundIschemic stroke (IS) is a global health issue linked to lipid metabolism and immune cell responses. This study uses Mendelian randomization (MR) to identify genetic risk factors for IS subtypes using comprehensive genetic data from lipidomic ...
Haohao Chen   +9 more
doaj   +1 more source

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