Results 11 to 20 of about 3,448 (206)

Objective assessment of alcohol consumption in early pregnancy using phosphatidylethanol: a cross‐sectional study [PDF]

BMC Pregnancy and Childbirth, 2021
Background Alcohol consumption during pregnancy is associated with major birth defects and developmental disabilities. Questionnaires concerning alcohol consumption during pregnancy underestimate alcohol use while the use of a reliable and objective ...
Leonieke J. Breunis, Sophie Wassenaar, Barbara J. Sibbles, Ab A. Aaldriks, Hilmar H. Bijma, Eric A.P. Steegers, Birgit C.P. Koch   +6 more
doaj   +2 more sources

Effect of the MyDéfi Smartphone Application on Binge Drinking Among University Students: Protocol of a Double‐Blind Multicenter Prospective National Randomized Controlled Trial Using Phosphatidylethanol as a Biomarker—The SMARTBINGE Trial

International Journal of Methods in Psychiatric Research
Objective The purpose of this paper is to describe a study protocol of a clinical trial exploring the effectiveness of the new mobile application MyDéfi proposing personalized feedback, on both alcohol consumption and quality of life, as well as the ...
Camille André, Pierre Sauton, Méléna Dreinaza, Momar Diouf, Sandra Bodeau, Margaret Martinetti, Raphaël Trouillet, Clara deGroote, Jean‐Louis Nandrino, Adèle Alexandre, Farid Benzerouk, Fabien Gierski, Pascal Perney, Laure Grellet, Judith André, Mickael Naassila   +15 more
doaj   +2 more sources

Humoral immune response to phosphatidylethanol

, 2011
Abstract Heavy alcohol consumption places a substantial burden on health all over the world. Metabolites of alcohol evoke alterations that lead to tissue damage in many organs. Phosphatidylethanol (PEth) is a unique phospholipid formed in the cellular membranes during the metabolism of ethanol after alcohol consumption.
Nissinen, A. (Antti)
openaire   +2 more sources

Phosphatidylethanol in Blood as a Marker of Alcohol Dependence

Archives of Psychiatry Research : An International Journal of Psychiatry and Related Sciences
Aim: To establish the cut-off value of phosphatidylethanol (PEth) concentration in the blood for detecting alcohol dependence. Materials and Methods: Using the method of high-performance liquid chromatography - tandem mass spectrometry (HPLC - MS), the concentration of PEth in the blood of 127 alcohol-dependent men undergoing hospital treatment was ...
Razvodovsky, Yury Evgeny, Schuriberco, Aleksey Vladimirovitz   +1 more
openaire   +2 more sources

Decline of phosphatidylethanol (B-PEth) during abstinence in patients with alcohol use disorder undergoing withdrawal treatment, and the correlation of B-PEth with self-reported alcohol intake. [PDF]

Addiction
Abstract Background and aim Accurately estimating alcohol consumption is crucial for clinical decision‐making and monitoring treatment outcomes. Phosphatidylethanol in blood (B‐PEth), a direct alcohol biomarker, is currently the most reliable indicator of alcohol intake, with a detection window of several weeks; however, the factors influencing the ...
de Bejczy A, Walther L, Nilsson-Wallmark C, Askerup B, Isaksson A.   +4 more
europepmc   +2 more sources

Examining Phosphatidylethanol (PEth) Formation Rates Within and Between Subjects in Ex Vivo Whole Blood. [PDF]

Drug Test Anal
PEth formation rate increased with increasing ethanol concentration with variability between participants but was mostly consistent within‐subject. No relationship was observed between phosphatidylcholine concentrations and PEth formation rates. PEth concentrations should be used to monitor an individual's ethanol use over time, rather than compared ...
Stark HG, Sanchez JJ, Hill-Kapturczak N, Roache JD, Ginsburg BC.   +4 more
europepmc   +2 more sources

Isomer Composition Assessment of Synthetic Phosphatidylethanol by Collision-Induced and Ozone-Induced Dissociation Mass Spectrometry. [PDF]

Drug Test Anal
The direct blood-alcohol biomarker phosphatidylethanol (PEth), especially its most abundant analogue 1-palmitoyl-2-oleoyl-sn-phosphatidylethanol (PEth 16:0/18:1) has gained increasing relevance in clinical and forensic applications for assessing alcohol ...
Bantle M, Long JOT, Brydon SC, Young RSE, Blanksby SJ, Weinmann W, Luginbühl M.   +6 more
europepmc   +2 more sources

Debating capabilities of biochemical markers of liver function in patients with alcoholic liver cirrhosis

Медицинский совет, 2022
Introduction. The diagnosis of alcohol-related liver disease is limited by the lack of a tool to reliably identify whether the present deterioration in the patient’s condition is due to alcohol consumption or other causes.Purpose.
K. A. Ikonnikova, N. N. Eroshchenko, V. N. Drozdov, E. V. Shikh, S. Yu. Serebrova   +4 more
doaj   +1 more source

False Positive Results of Phosphatidylethanol (PEth) Quantitation in Dried Blood Spots (DBS): The Influence of Alcohol Vapors

Separations, 2022
The role of phosphatidylethanol (PEth) as an alcohol consumption marker is increasing in clinical and forensic medicine. During the COVID-19 pandemic, the role of hygiene increased, and it became common practice to use disinfectants almost everywhere ...
Anton Bashilov, Sergey Osipenko, Karolina Ikonnikova, Oxana Kovaleva, Boris Izotov, Evgeny Nikolaev, Yury Kostyukevich   +6 more
doaj   +1 more source

Exploring Phosphatidylethanol Cutoffs for Self-Reported Unhealthy Alcohol Use: An International Multi-Site Analysis. [PDF]

Alcohol Clin Exp Res (Hoboken)
Phosphatidylethanol (PEth) is a biomarker that quantifies total drinking over the past 2–4 weeks, but PEth cutoffs for unhealthy drinking have not been well‐examined. Using self‐report as the reference standard, we estimated PEth cutoffs in a multinational sample and found substantial variability in cutoffs by region and by some other characteristics ...
Murnane PM, Xia F, Afshar M, Brown JL, Chamie G, Cook RL, Couture MC, DiClemente RJ, Fatch R, Ferguson T, Francis JM, Haberer JE, Jacobson KR, Justice AC, Kapiga S, Kim TW, Krupitsky E, Marcus GM, Molina PE, Muyindike WR, Myers B, Page K, Phillips SA, Piano MR, Richards VL, So-Armah K, Stewart S, Sulkowski MS, Tien PC, Woolf-King S, Hahn JA.   +30 more
europepmc   +2 more sources