Results 31 to 40 of about 3,448 (206)

Phosphatidylethanol and Alcohol Consumption in Reproductive Age Women [PDF]

Alcoholism: Clinical and Experimental Research, 2010
Background:  Fetal alcohol disorders are preventable, but self‐reported alcohol consumption can be misleading and impede effective treatment. Biomarkers represent an alternative method for assessing alcohol use, and this study evaluated the relationship between blood phosphatidylethanol (PEth) and alcohol use in a sample of reproductive age women ...
Scott H, Stewart, Tameeka L, Law, Patrick K, Randall, Roger, Newman   +3 more
openaire   +2 more sources

Biomolecules and Biomarkers Used in Diagnosis of Alcohol Drinking and in Monitoring Therapeutic Interventions

Biomolecules, 2015
Background: The quantitative, measurable detection of drinking is important for the successful treatment of alcohol misuse in transplantation of patients with alcohol disorders, people living with human immunodeficiency virus that need to adhere to ...
Radu M. Nanau, Manuela G. Neuman
doaj   +1 more source

PHOSPHATIDYLETHANOL FORMATION AND DEGRADATION IN HUMAN AND RAT BLOOD [PDF]

Alcohol and Alcoholism, 2004
To investigate the rate of formation and degradation of phosphatidylethanol (PEth) in rat blood as compared to human blood, as a model for a biological marker for ethanol exposure.Rats were given 9% ethanol in liquid diet for 30 days. Control rats were pair fed with a control liquid diet.
Steina, Aradóttir, Kristian, Moller, Christer, Alling   +2 more
openaire   +2 more sources

Phosphatidylethanol in steatotic liver disease [PDF]

Journal of Hepatology
Steatotic liver disease (SLD) encompasses metabolic dysfunction-associated steatotic liver disease (MASLD), alcohol-related liver disease (ALD), and their combination (MetALD). Distinguishing these subclasses relies on accurately assessing current alcohol intake, particularly as subclass-specific drug therapies become available.
Nikolaj Torp, Mads Israelsen, Maja Thiele, Mary E. Rinella, Aleksander Krag   +4 more
openaire   +2 more sources

Phosphatidylethanol affects inositol 1,4,5-trisphosphate levels in NG108-15 neuroblastoma x glioma hybrid cells

, 1993
Phosphatidylethanol is formed by phospholipase D in animal cells exposed to ethanol. Previous reports have demonstrated that the degradation of phosphatidylethanol is slow, indicating that this lipid may be present in the cells after ethanol itself has ...
Alling, Christer, Gustavsson, L, Rodriguez, F D, Lundqvist, C, Simonsson, Per   +4 more
core   +2 more sources

Calcitriol transmembrane signalling: regulation of rat muscle phospholipase D activity

Journal of Lipid Research, 1998
In rat skeletal muscle, calcitriol, the hormonal form of vitamin D3, rapidly stimulates the biphasic formation of diacylglycerol (DAG), the second phase being independent of phosphoinositide hydrolysis driven by phospholipase C.
Maria Marta Facchinetti, Ricardo Boland, Ana R. de Boland   +2 more
doaj   +1 more source

Biomarker Signatures to Monitor Alcohol Consumption and Induced Organ Damage [PDF]

Journal of Clinical and Diagnostic Research, 2021
The difficulty to differentiate long duration alcoholic behaviours is a major obstacle in the diagnosis and its treatment. Biomarkers in alcoholism are indicative of recent alcohol consumption or alcohol-induced organ damage.
Joy M Liji, PR Varghese, Susheela JacobInnah, Praveenlal Kuttichira   +3 more
doaj   +1 more source

Quantitative determination of phosphatidylethanol in dried blood spots for monitoring alcohol abstinence. [PDF]

, 2021
Phosphatidylethanol (PEth), which is formed by enzymatic reaction between ethanol and phosphatidylcholine, is a direct marker for alcohol usage. PEth has a long elimination half-life (~5-10 d) and specimens can be sampled using minimally invasive ...
Schröck, Alexandra, Weinmann, Wolfgang, Stefan Gaugler, Frederike Stöth, Luginbühl, Marc, Stöth, Frederike, Wolfgang Weinmann, Marc Luginbühl, Alexandra Schröck, Gaugler, Stefan   +9 more
core   +1 more source

Role of cholesterol in the modulation of interdigitation in phosphatidylethanols

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1998
Phosphatidylethanol (Peth) is formed in biological membranes when ethanol replaces water in the transphosphatidylation reaction catalyzed by phospholipase D. This charged lipid accumulates in the presence of ethanol, and it has unusual properties that can influence membrane structure and function.
Bondar, Olga P, Rowe, Elizabeth S
openaire   +2 more sources

Metabolomics Profiling of Vitamin D Status in Relation to Dyslipidemia

Metabolites, 2022
Vitamin D deficiency is a global disorder associated with several chronic illnesses including dyslipidemia and metabolic syndrome. The impact of this association with both dyslipidemia and vitamin D deficiency on metabolomics profile is not yet fully ...
Hanaa Mousa, Mohamed A. Elrayess, Ilhame Diboun, Simon K. Jackson, Susu M. Zughaier   +4 more
doaj   +1 more source