Results 31 to 40 of about 3,564 (210)

PHOSPHATIDYLETHANOL FORMATION AND DEGRADATION IN HUMAN AND RAT BLOOD [PDF]

Alcohol and Alcoholism, 2004
To investigate the rate of formation and degradation of phosphatidylethanol (PEth) in rat blood as compared to human blood, as a model for a biological marker for ethanol exposure.Rats were given 9% ethanol in liquid diet for 30 days. Control rats were pair fed with a control liquid diet.
Steina, Aradóttir, Kristian, Moller, Christer, Alling   +2 more
openaire   +2 more sources

Phosphatidylethanol Accumulation Promotes Intestinal Hyperplasia by Inducing ZONAB-Mediated Cell Density Increase in Response to Chronic Ethanol Exposure [PDF]

, 2007
International audienceChronic alcohol consumption is associated with increased risk of gastrointestinal cancer. High concentrations of ethanol trigger mucosal hyperregeneration, disrupt cell adhesion, and increase the sensitivity to carcinogens.
Frohman, Michael, Crespy, Philippe, Joubert, Dominique, Darido, Charbel, Bali, Jean-Pierre, Bourgaux, Jean-François, Pannequin, Julie, Hollande, Frédéric, Delaunay, Nathalie, Balda, Maria, Matter, Karl, Maurice, Tangui   +11 more
core   +1 more source

Association between phosphatidylethanol-measured alcohol use with HIV virologic non-suppression and all-cause mortality risk among people with HIV (PWH) on antiretroviral therapy (ART)

, 2023
Association between phosphatidylethanol-measured alcohol use with HIV virologic non-suppression and all-cause mortality risk among people with HIV (PWH) on antiretroviral therapy ...
Kaku So-Armah, Phyllis Tien, Gabriel Chamie, Judith Hahn, Winnie Muyindike, Cristina Espinosa da Silva, Evgeny Krupitsky, Robin Fatch, Julian Adong, Elena Blokhina, Brian Beesiga, Nneka Emenyonu, Sarah Puryear, Frank Palella, Kara Marson, Aaron Scheffler, Jeremy Kane   +16 more
core   +1 more source

Calcitriol transmembrane signalling: regulation of rat muscle phospholipase D activity

Journal of Lipid Research, 1998
In rat skeletal muscle, calcitriol, the hormonal form of vitamin D3, rapidly stimulates the biphasic formation of diacylglycerol (DAG), the second phase being independent of phosphoinositide hydrolysis driven by phospholipase C.
Maria Marta Facchinetti, Ricardo Boland, Ana R. de Boland   +2 more
doaj   +1 more source

Additional file 2 of Identification of unhealthy alcohol use by self-report and phosphatidylethanol (PEth) blood concentrations in an acute psychiatric department

, 2022
Additional file 2: Supplementary Table 1. Phosphatidylethanol (PEth) concentrations in μmol/L in the complete study population, and in women and men shown ...
Arne Einar Vaaler (8152623), Olav Spigset (773918), Rolf Wilhelm Gråwe (12444494), Trine Finanger (12444485), Trine Naalsund Andreassen (12444491), Ragnhild Bergene Skråstad (12444497), Trond Oskar Aamo (12444488)   +6 more
core   +1 more source

Biomarker Signatures to Monitor Alcohol Consumption and Induced Organ Damage [PDF]

Journal of Clinical and Diagnostic Research, 2021
The difficulty to differentiate long duration alcoholic behaviours is a major obstacle in the diagnosis and its treatment. Biomarkers in alcoholism are indicative of recent alcohol consumption or alcohol-induced organ damage.
Joy M Liji, PR Varghese, Susheela JacobInnah, Praveenlal Kuttichira   +3 more
doaj   +1 more source

Trinkstudie zur Eingrenzung einer Mindestalkoholmenge zur Bestimmung von Phosphatidylethanol

, 2023
Das Fahren unter Alkoholeinfluss und Nicht-Einhalten der Abstinenz sind weltweit nach wie vor ein großes Problem. Neben Ethylglucuronid im Urin oder Haar ist Phosphatidylethanol (PEth) ein vielversprechender direkter Alkohol-Biomarker zur Bestimmung von ...
Kotzerke, Ephraim Johannes
core   +1 more source

Role of cholesterol in the modulation of interdigitation in phosphatidylethanols

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1998
Phosphatidylethanol (Peth) is formed in biological membranes when ethanol replaces water in the transphosphatidylation reaction catalyzed by phospholipase D. This charged lipid accumulates in the presence of ethanol, and it has unusual properties that can influence membrane structure and function.
Bondar, Olga P, Rowe, Elizabeth S
openaire   +2 more sources

Phosphatidylethanol Levels, As a Marker of Alcohol Consumption, Are Associated With Risk of Intracerebral Hemorrhage

, 2020
Background and Purpose: Previous observational studies have shown a moderately increased risk of intracerebral hemorrhage (ICH) with high self-reported alcohol consumption.
Johansson, Lars,, Pennlert, Johanna,, Lind, Marcus,, Söderberg, Stefan,, Johansson, Kristina,, Jansson, Jan-Håkan,   +5 more
core   +1 more source

Metabolomics Profiling of Vitamin D Status in Relation to Dyslipidemia

Metabolites, 2022
Vitamin D deficiency is a global disorder associated with several chronic illnesses including dyslipidemia and metabolic syndrome. The impact of this association with both dyslipidemia and vitamin D deficiency on metabolomics profile is not yet fully ...
Hanaa Mousa, Mohamed A. Elrayess, Ilhame Diboun, Simon K. Jackson, Susu M. Zughaier   +4 more
doaj   +1 more source