Results 21 to 30 of about 3,564 (210)

Exploring Phosphatidylethanol Cutoffs for Self-Reported Unhealthy Alcohol Use: An International Multi-Site Analysis. [PDF]

Alcohol Clin Exp Res (Hoboken)
Phosphatidylethanol (PEth) is a biomarker that quantifies total drinking over the past 2–4 weeks, but PEth cutoffs for unhealthy drinking have not been well‐examined. Using self‐report as the reference standard, we estimated PEth cutoffs in a multinational sample and found substantial variability in cutoffs by region and by some other characteristics ...
Murnane PM, Xia F, Afshar M, Brown JL, Chamie G, Cook RL, Couture MC, DiClemente RJ, Fatch R, Ferguson T, Francis JM, Haberer JE, Jacobson KR, Justice AC, Kapiga S, Kim TW, Krupitsky E, Marcus GM, Molina PE, Muyindike WR, Myers B, Page K, Phillips SA, Piano MR, Richards VL, So-Armah K, Stewart S, Sulkowski MS, Tien PC, Woolf-King S, Hahn JA.   +30 more
europepmc   +2 more sources

Phosphatidylethanol blood analysis

Annales de Biologie Clinique, 2019
This article aims to place the phosphatidylethanol (PEth) blood test in the detection area of ethanol consumption causing alcohol-related disorders, to present the current methods of analysis, data on interpretation, some practical applications and the prospects of use of this biomarker. PEth is a minor metabolite of ethanol.
Hakim, Florian, Wiart, Jean-Francois, Menard, Olivier, Allorge, Delphine, Gaulier, Jean-Michel   +4 more
openaire   +4 more sources

Assessing the sensitivity and specificity of phosphatidylethanol (PEth) cutoffs to identify alcohol exposed pregnancies

Current Research in Toxicology, 2023
In the literature on alcohol use biomarkers, there has been debate as to what a valid and/or utilitarian cut off level should be for various research applications.
Julie M. Hasken, Anna-Susan Marais, Marlene M. de Vries, Wendy O. Kalberg, David Buckley, Charles D.H. Parry, Soraya Seedat, Philip A. May   +7 more
doaj   +1 more source

Phosphatidylethanol in Maternal or Neonatal Blood to Detect Alcohol Exposure during Pregnancy: A Systematic Review

Life, 2022
Background: Alcohol consumption during pregnancy, even at low doses, may damage the fetus. Pregnant women tend to underreport their alcohol consumption generating the need for sensitive and specific biomarkers, among which PEth has emerged due to its ...
Lisa Franceschetto, Matteo Perilli, Alessandro Cinquetti, Chiara Giraudo, Mario Gardi, Giovanni Cecchetto, Guido Viel   +6 more
doaj   +1 more source

Thermotropic properties of phosphatidylethanols

Biophysical Journal, 1996
Phosphatidylethanol is formed when ethanol substitutes in the transphosphatidylation reaction catalyzed by phospholipase D. The structural and thermotropic properties of dipalmitoylphosphatidylethanol and dimyristoylphosphatidylethanol have been studied using differential scanning calorimetry, fluorescence spectroscopy, and 31P nuclear magnetic ...
Bondar, O.P., Rowe, E.S.
openaire   +2 more sources

Phosphatidylethanol affects inositol 1,4,5-trisphosphate levels in NG108-15 neuroblastoma x glioma hybrid cells

, 1993
Phosphatidylethanol is formed by phospholipase D in animal cells exposed to ethanol. Previous reports have demonstrated that the degradation of phosphatidylethanol is slow, indicating that this lipid may be present in the cells after ethanol itself has ...
Gustavsson, L, Rodriguez, F D, Lundqvist, C, Simonsson, Per,, Alling, Christer,, Lund University.   +5 more
core   +2 more sources

Biomolecules and Biomarkers Used in Diagnosis of Alcohol Drinking and in Monitoring Therapeutic Interventions

Biomolecules, 2015
Background: The quantitative, measurable detection of drinking is important for the successful treatment of alcohol misuse in transplantation of patients with alcohol disorders, people living with human immunodeficiency virus that need to adhere to ...
Radu M. Nanau, Manuela G. Neuman
doaj   +1 more source

Mixed-methods trial of a phosphatidylethanol-based contingency management intervention to initiate and maintain alcohol abstinence in formerly homeless adults with alcohol use disorders

Contemporary Clinical Trials Communications, 2021
Background: Contingency management (CM) is an intervention where incentives are provided in exchange for biochemically confirmed alcohol abstinence.
Elizabeth R. Fraser, Nathalie Hill-Kapturczak, Julianne Jett, Rachael Beck, Oladunni Oluwoye, Liat S. Kriegel, Karl C. Alcover, Sterling McPherson, Leopoldo J. Cabassa, Martin Javors, Michael G. McDonell   +10 more
doaj   +1 more source

Phosphatidylethanol and Alcohol Consumption in Reproductive Age Women [PDF]

Alcoholism: Clinical and Experimental Research, 2010
Background:  Fetal alcohol disorders are preventable, but self‐reported alcohol consumption can be misleading and impede effective treatment. Biomarkers represent an alternative method for assessing alcohol use, and this study evaluated the relationship between blood phosphatidylethanol (PEth) and alcohol use in a sample of reproductive age women ...
Scott H, Stewart, Tameeka L, Law, Patrick K, Randall, Roger, Newman   +3 more
openaire   +2 more sources

Phosphatidylethanol in steatotic liver disease [PDF]

Journal of Hepatology
Steatotic liver disease (SLD) encompasses metabolic dysfunction-associated steatotic liver disease (MASLD), alcohol-related liver disease (ALD), and their combination (MetALD). Distinguishing these subclasses relies on accurately assessing current alcohol intake, particularly as subclass-specific drug therapies become available.
Nikolaj Torp, Mads Israelsen, Maja Thiele, Mary E. Rinella, Aleksander Krag   +4 more
openaire   +2 more sources