Results 41 to 50 of about 3,564 (210)

Neurofilament Light Chain in Cerebrospinal Fluid and Blood Identifies Patients With Minimal and Overt Hepatic Encephalopathy. [PDF]

Liver Int
ABSTRACT Background Minimal hepatic encephalopathy (MHE) is an underdiagnosed complication of liver cirrhosis, associated with progression to overt hepatic encephalopathy (HE). The Portosystemic Hepatic Encephalopathy Score (PHES) is the recommended diagnostic standard, but its use is hindered by resource constraints and limited accuracy. Neurofilament
Jonasson E, Grønkjær LL, Jacobsen BG, Olsen DA, Wernberg CW, Kuhle J, Madsen JS, Sejbaek T, Lauridsen MM.   +8 more
europepmc   +2 more sources

Effects of Three Extraction Methods on Avocado Oil Lipid Compounds Analyzed via UPLC-TOF-MS/MS with OPLS-DA

Foods, 2023
Avocado oil is excellent functional oil. Effects of three extraction methods (squeezing extraction, supercritical carbon dioxide extraction, and aqueous extraction) on the species, composition, and contents of lipids in avocado oil were analyzed via ...
Yijun Liu, Qiuyu Xia, Yangyang Qian, Yu Kuang, Jiameng Liu, Lijing Lin   +5 more
doaj   +1 more source

Effects of ethanol and ethanol metabolites on intrinsic function of mesenteric resistance arteries.

PLoS ONE, 2019
Evidence suggests that ethanol-induced hypertension is associated with increased cardiovascular responsiveness to vasopressors in vivo and enhanced reactivity of isolated arteries to vasopressors ex vivo. The underlying mechanisms are not well understood
Jonathan M Eby, Matthias Majetschak
doaj   +1 more source

Evaluation of phosphatidylethanol by ELISA for detection of excessive alcohol use compared with traditional biomarkers: a case-control study

Psychiatry and Clinical Psychopharmacology, 2017
Objective: The highly sensitive chromatographic methods for quantifying phosphatidylethanol (PEth) require high levels of expertice and expensive instrumentation.
Mehmet Bulent Sonmez, Rugul Kose Cinar, Yasemin Gorgulu, Evnur Kahyaci Kilic, Aycan Unal   +4 more
doaj   +1 more source

Prognostic significance of prior alcohol use disorder in patients with presumed metabolic dysfunction‐associated steatotic liver disease: A large multi‐center cohort study

Addiction, EarlyView.
Abstract Background and aims Alcohol use disorder (AUD) follows a chronic, relapsing course but is often overlooked when alcohol consumption is minimal at the time of evaluation. We aimed to assess the prognostic impact of a prior AUD diagnosis on liver‐related outcomes in patients with presumed metabolic dysfunction‐associated steatotic liver disease (
Butros Fakhoury, Jinye Liu, Vinay Jahagirdar, Kaanthi Rama, Gerald Scott Winder, Luis Antonio Díaz, Juan Pablo Arab   +6 more
wiley   +1 more source

Improved detection of alcohol consumption using the novel marker phosphatidylethanol in the transplant setting: results of a prospective study. [PDF]

, 2017
Phosphatidylethanol (PEth) is a new, highly specific alcohol marker. The aim of this study was to assess its diagnostic value in the liver transplant setting.
Lohse, Ansgar, Nashan, Björn, Weinmann, Wolfgang, Skopp, Gisela, Hilke Andresen-Streichert, Müller, Alexander, Pischke, Sven, Vettorazzi, Eik, Sven Pischke, Gisela Skopp, Andresen-Streichert, Hilke, Schröck, Alexandra, Björn Nashan, Eik Vettorazzi, Ansgar Lohse, Beres, Yannick, Sterneck, Martina, Martina Sterneck, Alexander Müller, Wolfgang Weinmann, Yannick Beres, Alexandra Schröck, Schröck A, Nashan B, Skopp G, Müller A, Andresen-Streichert H, Weinmann W, Sterneck M, Pischke S, Lohse A, Vettorazzi E, Beres Y   +32 more
core   +1 more source

Comparison of self-reported alcohol consumption to phosphatidylethanol measurement among HIV-infected patients initiating antiretroviral treatment in southwestern Uganda. [PDF]

PLoS ONE, 2014
Alcohol consumption among HIV-infected patients may accelerate HIV disease progression or reduce antiretroviral therapy adherence. Self-reported alcohol use is frequently under-reported due to social desirability and recall bias.
Francis Bajunirwe, Jessica E Haberer, Yap Boum, Peter Hunt, Rain Mocello, Jeffrey N Martin, David R Bangsberg, Judith A Hahn   +7 more
doaj   +1 more source

Alcohol‐Associated Liver Disease: Epidemiology, Pathogenesis, and Emerging Therapeutic Targets

MedComm, Volume 7, Issue 11, November 2026.
ALD imposes a growing global burden influenced by alcohol consumption, genetic susceptibility, and obesity. Its pathogenesis involves interactions among ethanol metabolism, oxidative stress, innate immune activation, regulated cell death, and disruption of the gut–liver axis.
Shuyan Wang, Yirui Hu, Huikuan Chu
wiley   +1 more source

Confounders of Serum Phosphatidylethanol: Role of Red Blood Cell Turnover and Cirrhosis

Hepatic Medicine: Evidence and Research, 2023
Marc Bartel,1,* Vanessa Hofmann,1,* Shijin Wang,2,3 Johannes Mueller,2 Tom R Sundermann,1 Sebastian Mueller2 1Institute of Forensic and Traffic Medicine, Heidelberg University Hospital, Heidelberg, Germany; 2Center for Alcohol Research ...
Bartel M, Hofmann V, Wang S, Mueller J, Sundermann TR, Mueller S   +5 more
doaj  

Phosphatidylethanol in Postmortem Brain and Serum Ethanol at Time of Death [PDF]

Alcoholism: Clinical and Experimental Research, 2016
BackgroundPhosphatidylethanol (PEth) is a metabolite of ethanol (EtOH), and its concentration in whole blood samples is a direct biomarker of alcohol consumption. Because PEth is also present in the brain and incorporated in lipid membranes, it can be used to classify deceased individuals on alcohol consumption status at the time of death.
Peter M, Thompson, Nathalie, Hill-Kapturczak, Marisa, Lopez-Cruzan, Luis A, Alvarado, Alok K, Dwivedi, Martin A, Javors   +5 more
openaire   +2 more sources