Results 61 to 70 of about 3,448 (206)

Identification of 48 homologues of phosphatidylethanol in blood by LC-ESI-MS/MS [PDF]

, 2010
Phosphatidylethanol (PEth) is an abnormal phospholipid carrying two fatty acid chains. It is only formed in the presence of ethanol via the action of phospholipase D (PLD).
Gnann, Heike, Weinmann, Wolfgang, Engelmann, Claudia, Skopp, Gisela, Engelmann, C, Auwärter, V, Weinmann, W, Dresen, Sebastian, Dresen, S, Winkler, Michaela, Ferreirós, N, Wurst, F M, Skopp, G, Ferreirós, Nerea, Auwärter, Volker, Gnann, H, Winkler, M, Wurst, Friedrich Martin   +17 more
core   +2 more sources

Association between phosphatidylethanol-measured alcohol use with HIV virologic non-suppression and all-cause mortality risk among people with HIV (PWH) on antiretroviral therapy (ART)

, 2023
Association between phosphatidylethanol-measured alcohol use with HIV virologic non-suppression and all-cause mortality risk among people with HIV (PWH) on antiretroviral therapy ...
Kaku So-Armah, Phyllis Tien, Gabriel Chamie, Judith Hahn, Winnie Muyindike, Cristina Espinosa da Silva, Evgeny Krupitsky, Robin Fatch, Julian Adong, Elena Blokhina, Brian Beesiga, Nneka Emenyonu, Sarah Puryear, Frank Palella, Kara Marson, Aaron Scheffler, Jeremy Kane   +16 more
core   +1 more source

Evaluating the Impact of Phosphatidylethanol Testing on Hospital Outcomes

Gastroenterology Research
Alcohol dependence remains a significant global health issue, exacerbated by the coronavirus disease 2019 (COVID-19) pandemic. Phosphatidylethanol (PEth), a direct biomarker of recent alcohol consumption, offers improved specificity, sensitivity, and a longer detection window of 2 - 4 weeks compared to traditional biomarkers.
Haddadin, Rakahn, Molina, Steven, Trad, George, Ryan, John, Gish, Robert   +4 more
openaire   +2 more sources

Multifactor Risk Stratification for Post‐Transplant Alcohol Relapse Using Abstinence, Psychosocial, and Socioeconomic Factors

Annals of Gastroenterological Surgery, Volume 10, Issue 4, Page 1217-1230, July 2026.
Alcohol relapse after liver transplantation is difficult to predict using abstinence duration alone. We developed a multifactor model integrating abstinence duration, psychosocial risk (SIPAT), and socioeconomic context (AUC 0.70). This approach may support individualized risk assessment and tailored follow‐up intensity; external validation is needed ...
Ayato Obana, Garren Montgomery, Miho Akabane, Matthew Hamilton, Navdeep Singh, Musab Alebrahim, Austin Schenk, Sylvester Black, Kenneth Washburn, Khalid Mumtaz   +9 more
wiley   +1 more source

Prevalence of Alcohol Consumption in Emergency department presentations (PACE) in Queensland, Australia, using alcohol biomarkers ethanol and phosphatidylethanol: an observational study protocol

BMJ Open, 2021
Introduction Alcohol use in patients presenting to the emergency department (ED) is a significant problem in many countries. There is a need for valid and reliable surveillance of the prevalence of alcohol use in patients presenting to the ED, to provide
Tegwen Howell, Jacelle Warren, Cate M Cameron, Kirsten Vallmuur, Victoria McCreanor, Gary Mitchell, Silvia Manzanero, Michael Schuetz, Kim A Vuong, Jacobus P J Ungerer, Brett McWhinney, Clifford Pollard, Anna Zournazi   +12 more
doaj   +1 more source

Alcohol Consumption Is a Risk Factor of Surgical Site Infection After Minimally Invasive Surgery: A Secondary Observational Analysis of a Clinical Trial

Annals of Gastroenterological Surgery, Volume 10, Issue 4, Page 1337-1345, July 2026.
Alcohol consumption was independently associated with Surgical Site Infection in the gastroenterological Minimally Invasive Surgery. Whether preoperative abstinence from alcohol prevents the occurrence of SSI warrants further investigation. ABSTRACT Background Surgical site infection (SSI) is one of the postoperative complications. Risk factors for SSI
Toshiya Akai, Makoto Takeda, Eisuke Booka, Tomohiro Matsumoto, Masayo Takaoka, Mayu Sakata, Yoshifumi Morita, Hirotoshi Kikuchi, Yoshihiro Hiramatsu, Hiroya Takeuchi   +9 more
wiley   +1 more source

Phosphatidylethanol and ethyl glucuronide to categorize alcohol consumption in alcohol-related cirrhosis

JHEP Reports
Background & Aims: Phosphatidylethanol (PEth) is an alcohol-use biomarker that could bridge the detection windows of urinary ethyl glucuronide (uEtG) and scalp hair ethyl glucuronide (hEtG), but has been rarely validated in patients with liver ...
Benedict T.K. Vanlerberghe, Catalina Dumitrascu, Nele Van den Eede, Hugo Neels, Hannah van Malenstein, Tom J.G. Gevers, Matthijs Kramer, Lukas Van Melkebeke, Ad A.M. Masclee, Douwe de Boer, Schalk van der Merwe, Frederik Nevens, Alexander L.N. van Nuijs, Jef Verbeek   +13 more
doaj   +1 more source

Protein kinase Cζ regulates phospholipase D activity in rat-1 fibroblasts expressing the α_1A adrenergic receptor

BMC Cell Biology, 2004
Background Phenylephrine (PHE), an α1 adrenergic receptor agonist, increases phospholipase D (PLD) activity, independent of classical and novel protein kinase C (PKC) isoforms, in rat-1 fibroblasts expressing α1A adrenergic receptors.
Bourgoin Sylvain G, Malik Kafait U, Saeed Abdelwahab E, Wiggins Monique T, Gandhi Gautam K, Parmentier Jean-Hugues   +5 more
doaj   +1 more source

Phosphatidylethanol in Postmortem Brain and Serum Ethanol at Time of Death [PDF]

Alcoholism: Clinical and Experimental Research, 2016
BackgroundPhosphatidylethanol (PEth) is a metabolite of ethanol (EtOH), and its concentration in whole blood samples is a direct biomarker of alcohol consumption. Because PEth is also present in the brain and incorporated in lipid membranes, it can be used to classify deceased individuals on alcohol consumption status at the time of death.
Peter M, Thompson, Nathalie, Hill-Kapturczak, Marisa, Lopez-Cruzan, Luis A, Alvarado, Alok K, Dwivedi, Martin A, Javors   +5 more
openaire   +2 more sources

Acute Liver Injury Following Outpatient Trimethoprim‐Sulfamethoxazole Use for Small Intestinal Bacterial Overgrowth: A Case Report

Clinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Drug‐induced liver injury (DILI) is a leading cause of acute liver failure in the United States and remains difficult to predict and diagnose. Trimethoprim‐sulfamethoxazole (TMP‐SMX) is widely prescribed and generally well tolerated, yet rare cases of severe idiosyncratic hepatotoxicity have been reported.
Kaylie Duit, Joseph Rattenni, Lauryn Hanson, Aaron R. Kunz   +3 more
wiley   +1 more source