Results 71 to 80 of about 3,564 (210)

Alcohol Biomarker Phosphatidylethanol as a Predictor of the Severity of Alcohol Withdrawal Syndrome.

, 2023
AIMS to investigate the relationship between phosphatidylethanol (PEth) and withdrawal severity in patients with alcohol use disorder (AUD). METHODS in 34 patients with AUD admitted for treatment of acute alcohol withdrawal, data were available ...
Novak, Lan, Bünter, Adina, Weinmann, Wolfgang, Stöth, Frederike, Wopfner, Alexander, Pfeifer, Philippe, Soravia, Leila M, Stöth, Frederike Theresa, Soravia, Leila, Frederike Stöth, Alexander Wopfner, Adina Bünter, Lan Novak, Leila M Soravia, Wolfgang Weinmann, Philippe Pfeifer   +15 more
core   +1 more source

Modulation of Insulin Sensitivity of Hepatocytes by the Pharmacological Downregulation of Phospholipase D

International Journal of Endocrinology, 2015
Background. The role of phospholipase D (PLD) as a positive modulator of glucose uptake activation by insulin in muscle and adipose cells has been demonstrated. The role of PLD in the regulation of glucose metabolism by insulin in the primary hepatocytes
Nataliya A. Babenko, Vitalina S. Kharchenko   +1 more
doaj   +1 more source

Multifactor Risk Stratification for Post‐Transplant Alcohol Relapse Using Abstinence, Psychosocial, and Socioeconomic Factors

Annals of Gastroenterological Surgery, Volume 10, Issue 4, Page 1217-1230, July 2026.
Alcohol relapse after liver transplantation is difficult to predict using abstinence duration alone. We developed a multifactor model integrating abstinence duration, psychosocial risk (SIPAT), and socioeconomic context (AUC 0.70). This approach may support individualized risk assessment and tailored follow‐up intensity; external validation is needed ...
Ayato Obana, Garren Montgomery, Miho Akabane, Matthew Hamilton, Navdeep Singh, Musab Alebrahim, Austin Schenk, Sylvester Black, Kenneth Washburn, Khalid Mumtaz   +9 more
wiley   +1 more source

Light-induced changes in fatty acid profiles of specific lipid classes in several freshwater phytoplankton species

Frontiers in Plant Science, 2016
We tested the influence of two light intensities [40 and 300 µmol PAR / (m² s)] on the fatty acid composition of three distinct lipid classes in four freshwater phytoplankton species.
Alexander eWacker, Maike ePiepho, John L Harwood, Irina A Guschina, Michael T Arts   +4 more
doaj   +1 more source

Alcohol Consumption Is a Risk Factor of Surgical Site Infection After Minimally Invasive Surgery: A Secondary Observational Analysis of a Clinical Trial

Annals of Gastroenterological Surgery, Volume 10, Issue 4, Page 1337-1345, July 2026.
Alcohol consumption was independently associated with Surgical Site Infection in the gastroenterological Minimally Invasive Surgery. Whether preoperative abstinence from alcohol prevents the occurrence of SSI warrants further investigation. ABSTRACT Background Surgical site infection (SSI) is one of the postoperative complications. Risk factors for SSI
Toshiya Akai, Makoto Takeda, Eisuke Booka, Tomohiro Matsumoto, Masayo Takaoka, Mayu Sakata, Yoshifumi Morita, Hirotoshi Kikuchi, Yoshihiro Hiramatsu, Hiroya Takeuchi   +9 more
wiley   +1 more source

Characterization of sialic acid index of plasma apolipoprotein J and phosphatidylethanol during alcohol detoxification--a pilot study

, 2011
Apolipoprotein J (ApoJ) is a component of plasma high-density lipoproteins. Previous studies have shown progressive recovery of ApoJ sialic acid content with increased duration of alcohol abstinence.
Lakshman, M. Raj, Raj Lakshman, Aradottir, Steina,, Christer Alling, Hahn, Judith A, Friedrich M. Wurst, Alling, Christer, Judith A. Hahn, Alling, Christer,, Paul Marques, Lakshman, Raj, Scott Tippetts, Weinmann, Wolfgang, Thon, Natasha, Aradottir, Steina, Steina Aradottir, Marques, Paul, Susanne Hartmann, Tippetts, Scott, Wurst, Friedrich M., Wurst, Friedrich M, Hartmann, Susanne, Natasha Thon, Wolfgang Weinmann, Lund University., Hahn, Judith A.   +25 more
core   +1 more source

Acute Liver Injury Following Outpatient Trimethoprim‐Sulfamethoxazole Use for Small Intestinal Bacterial Overgrowth: A Case Report

Clinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Drug‐induced liver injury (DILI) is a leading cause of acute liver failure in the United States and remains difficult to predict and diagnose. Trimethoprim‐sulfamethoxazole (TMP‐SMX) is widely prescribed and generally well tolerated, yet rare cases of severe idiosyncratic hepatotoxicity have been reported.
Kaylie Duit, Joseph Rattenni, Lauryn Hanson, Aaron R. Kunz   +3 more
wiley   +1 more source

Quantification of alcohol intake in patients with steatotic liver disease and excessive alcohol intake

JHEP Reports
Background & Aims: Quantifying alcohol intake is crucial for subclassifying participants with steatotic liver disease (SLD) and interpreting clinical trials of alcohol-related liver disease (ALD) and metabolic and alcohol-related liver disease ...
Emil Deleuran Hansen, Nikolaj Torp, Stine Johansen, Johanne Kragh Hansen, Marianne Lerbæk Bergmann, Camilla Dalby Hansen, Sönke Detlefsen, Peter Andersen, Ida Villesen, Katrine Bech, Katrine Thorhauge, Gitte Hedegaard Jensen, Katrine Prier Lindvig, Torben Hansen, Emmanuel A. Tsochatzis, Jonel Trebicka, Maja Thiele, Aleksander Krag, Mads Israelsen   +18 more
doaj   +1 more source

Fatty acid ethyl esters induce intestinal epithelial barrier dysfunction via a reactive oxygen species-dependent mechanism in a three-dimensional cell culture model.

PLoS ONE, 2013
Background & aimsEvidence is accumulating that ethanol and its oxidative metabolite, acetaldehyde, can disrupt intestinal epithelial integrity, an important factor contributing to ethanol-induced liver injury. However, ethanol can also be metabolized non-
Elhaseen Elamin, Ad Masclee, Kati Juuti-Uusitalo, Sven van Ijzendoorn, Freddy Troost, Harm-Jan Pieters, Jan Dekker, Daisy Jonkers   +7 more
doaj   +1 more source

Identification of 48 homologues of phosphatidylethanol in blood by LC-ESI-MS/MS [PDF]

, 2010
Phosphatidylethanol (PEth) is an abnormal phospholipid carrying two fatty acid chains. It is only formed in the presence of ethanol via the action of phospholipase D (PLD).
Gnann, Heike, Weinmann, Wolfgang, Engelmann, Claudia, Skopp, Gisela, Engelmann, C, Auwärter, V, Weinmann, W, Dresen, Sebastian, Dresen, S, Winkler, Michaela, Ferreirós, N, Wurst, F M, Skopp, G, Ferreirós, Nerea, Auwärter, Volker, Gnann, H, Winkler, M, Wurst, Friedrich Martin   +17 more
core   +2 more sources