Results 171 to 180 of about 85,741 (244)

Cross‐species transcriptomics uncovers shared responses to water deficiency in plants

The Plant Genome, Volume 19, Issue 4, December 2026.
Abstract Deepening our knowledge of conserved molecular mechanisms governing stress responses in plants is fundamental for identifying new core genes and processes involved in tolerance to adverse environmental conditions. For this purpose, we developed a bioinformatic pipeline to retrieve and integrate stress‐related RNA‐seq transcriptomic data from ...
Francesco Punzi, Diana Lucia Zuluaga, Qiao Wen Tan, Marek Mutwil, Gabriella Sonnante, Pasquale Luca Curci   +5 more
wiley   +1 more source

Deletion of phosphatidylethanolamine methyltransferase promotes the spontaneous development of hepatic steatosis, inflammation, and fibrosis in young mice. [PDF]

Clin Sci (Lond)
Perumal SK, Rajamanickam R, Arumugam MK, Chava S, Bellamkonda R, Mahalingam S, Osna NA, Trujillo-Gonzalez I, Fisher KW, Rasineni K, Kharbanda KK.   +10 more
europepmc   +1 more source

Expression of Human CYP2D6 in Artificial Cells Based on Polymer‐Lipid Hybrid Vesicles

ChemBioChem, Volume 27, Issue 21, 12 November 2026.
Expression of eGFP and human cytochrome P450 2D6 (CYP2D6) within the lumen of giant polymer‐lipid hybrid vesicles using a Leishmania tarentolae‐based cell‐free protein expression system is illustrated. Both proteins were expressed in the vesicle lumen, and low‐polymer‐content hybrid vesicles were the most suitable scaffolds for CYP2D6 expression with ...
Sarah Dahl, Paula De Dios Andres, Grégory Beaune, Jaakko V. I. Timonen, James Behrendorff, Kirill Alexandrov, Wayne Johnston, Brigitte Städler   +7 more
wiley   +1 more source

Time-Dependent Phospholipid Remodeling in Cultured Primary Mouse Hepatocytes: Associations with PEMT Status and Methionine Availability. [PDF]

Cells
Ma T, Zhou K, Zhu Y, Zhang J, Xie X, Zhang L, Ye C, Tu ZC.   +7 more
europepmc   +1 more source

Plasma Lipidomic Features of Adolescent Major Depressive Disorder and Lipid Changes After Fluoxetine Treatment

CNS Neuroscience &Therapeutics, Volume 32, Issue 11, November 2026.
Dysregulated plasma lipid homeostasis with aberrant triglycerides, lysophospholipids, and membrane sphingolipids represents a core pathological feature of adolescent major depressive disorder. Eight‐week fluoxetine treatment remodels lipid profiles including bile acid metabolites and modulates key signaling pathways, supporting novel lipid‐based ...
Chenxi Liu, Yao Li, Hanchen Hou, Jiamei Guo, Bingjie Qin, Xiaoxia Xu, Yuqian He, Tingting Lei, Fei Chen, Lige Zhang, Quanbing Liu, Li Gao, Jiaqi Shi, Haoran Xing, Teng Teng, Tian Qiu, Xinyu Zhou   +16 more
wiley   +1 more source

Prenatal Choline and Betaine Differentially Program Adult Hepatic One-Carbon Metabolism in Wistar Rats. [PDF]

J Agric Food Chem
Shelp GV, Tang J, Dong J, Al-Issa M, Butt N, Poole EM, Burns SE, Pannia E, Bakovic M, Cho CE.   +9 more
europepmc   +1 more source

XDH Inhibits the Progression of Colorectal Cancer via Regulating Ferritinophagy Signaling

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 11, November 2026.
XDH inhibits the progression of CRC via mediating ferritinophagy and ferroptosis. Therefore, XDH/ferritinophagy may be a potential target for CRC. ABSTRACT Xanthine dehydrogenase (XDH) is involved in the progression of various cancer. This study aimed to investigate its potential in colorectal cancer (CRC). Gene expression was determined using RT‐qPCR,
Huiying Zhang, Meimei Yan, Mengya Li, Junjiao Gu, Xintao Wang, Jin Ding, Suxia Luo   +6 more
wiley   +1 more source

Gut microbiome modulation by Veillonella ratti induces resistance to EAE pathogenesis via microbe-derived metabolites. [PDF]

Exp Mol Med
Sittipo P, Park JY, Tiffany E, Oh A, Moon S, Lee CH, Oh JS, Kim TY, Kweon MN, Choi J, Song KH, Lee DW, Nam MH, Hong SJ, Lee EY, Jeon SR, Song HY, Kim BS, Lee YK.   +18 more
europepmc   +1 more source

In Vivo 31P‐MRS of the Human Orthotopic Kidney at 3 Tesla

NMR in Biomedicine, Volume 39, Issue 11, November 2026.
31P‐MRS of healthy human orthotopic kidneys at 3T yielded improved spectral quality within a clinically feasible scan time. The resulting summed spectrum characterizes normal renal phosphorus metabolism and may serve as a reference for detecting metabolic alterations associated with kidney disease and transplantation.
Eva Carlsson, Jan Weis, Maria K. Svensson, Maysam Jafar, Per Liss, Amir Sedigh   +5 more
wiley   +1 more source

Glucose may be biotransformed and then react with alcohol, fats, endocannabinoids, or various amino acids to form dopamine or norepinephrine in vivo

Frontiers in Pharmacology
Paul J. Fitzgerald
doaj   +1 more source