Ceramide-C16 Is a Versatile Modulator of Phosphatidylethanolamine Polymorphism [PDF]
Mahmoudreza Doroudgar, Michel Lafleur
openalex +1 more source
This review reconsiders the amyloid cascade by placing lipid dynamics at its core. It shows that free lipids, governed by critical micellar concentration, act as pathological chaperones that redirect amyloid aggregation toward membrane‐damaging species.
Sofia Serravalle +6 more
wiley +1 more source
Spatial lipidomic and neuron-specific transcriptomic signatures in the nucleus accumbens reveal phospholipid dyshomeostasis in depression-related maladaptations. [PDF]
Camargo A +7 more
europepmc +1 more source
Promotion-resistant JB6 mouse epidermal cells exhibit defects in phosphatidylethanolamine synthesis and phorbol ester-induced phosphatidylcholine hydrolysis [PDF]
Zoltán Kiss, Brad GUYER, Zigang Dong
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Bioconjugation Strategies for Revealing the Roles of Glycerophospholipids in Cells
Glycerophospholipids are the main class of phospholipids, essential for membrane structure, compartmentalization, and cellular signaling. To study their roles, innovative probes and advanced bioconjugation strategies have been developed, including by de novo lipid synthesis and bioorthogonal conjugation chemistry.
Brice Beauvais +5 more
wiley +1 more source
Polystyrene Microplastics and Lead Co-Exposure Disturbed Hepatic Lipid Metabolism in C57BL/6 Mice. [PDF]
Gao B +7 more
europepmc +1 more source
Abstract 2311 Two Bridge-like lipid transfer proteins (BLTPs) transport phosphatidylethanolamine at membrane contact sites to facilitate GPI-anchored biogenesis and maintain plasma membrane fluidity [PDF]
Alexandre Toulmay +3 more
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Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
TIM-1 promotes infection with mosquito cell-derived alphaviruses through virion-associated phospholipids. [PDF]
Yoo JE +9 more
europepmc +1 more source
Phospholipase A2 (PLA2), a dormant enzyme, becomes lethal when activated—collapsing lungs in minutes. Our dual therapy (DOPS + varespladib) boosts survival from 0% to >90% in sepsis/ALI. A breakthrough for acute lung injury treatment. ABSTRACT This study reveals that phospholipase A2 (PLA2), normally stable and nontoxic, can be activated specifically ...
Jianyu Wang +7 more
wiley +1 more source

