Results 201 to 210 of about 105,655 (290)

Glucose may be biotransformed and then react with alcohol, fats, endocannabinoids, or various amino acids to form dopamine or norepinephrine in vivo

Frontiers in Pharmacology
Paul J. Fitzgerald
doaj   +1 more source

Citrate‐Dependent Activation of Acetyl CoA Carboxylase Promotes Renal Lipid Accumulation in a Rat Model of Chronic Kidney Disease

Acta Physiologica, Volume 242, Issue 5, May 2026.
ABSTRACT Background Abnormal accumulation of lipids within the kidney contributes to the progression of chronic kidney disease, but the underlying metabolic mechanisms remain unclear. Citrate is a central metabolite in cellular energy regulation and is frequently elevated in advanced kidney disease, yet its impact on renal lipid metabolism has not been
Marta Sanz‐Gómez, Beatriz Linillos‐Pradillo, Rubén Fernández de la Rosa, Isabel Aránguez, Reinhold Kreutz, Antonia García, Coral Barbas, Adrián Plaza, María S. Fernández‐Alfonso   +8 more
wiley   +1 more source

Genetic variants in acetylcholine processing and significant improvement with pyridostigmine in a patient with postural orthostatic tachycardia syndrome: a case report. [PDF]

Eur Heart J Case Rep
Stephenson KM, Foster B, Blitshteyn S.
europepmc   +1 more source

Upregulation of sphingomyelin and ABCA8 in response to TDP‐43 pathology in amyotrophic lateral sclerosis brain

Brain Pathology, Volume 36, Issue 3, May 2026.
Increases in sphingomyelin in response to TDP‐43 pathology in the disease‐affected motor cortex of amyotrophic lateral sclerosis (ALS) brain. Abstract Amyotrophic lateral sclerosis (ALS) is a rapidly progressing neurodegenerative disease characterized by the degeneration of motor neurons and the presence of TAR DNA‐binding protein 43 (TDP‐43 ...
Finula I. Isik, Russell Pickford, Nicolas Dzamko, Kerry‐Anne Rye, Woojin Scott Kim   +4 more
wiley   +1 more source

Quantification and Localisation of New Brain Lipid Synthesis Using Deuterium Oxide and High Resolution Mass Spectrometry

Angewandte Chemie, Volume 138, Issue 18, 27 April 2026.
Liquid chromatography tandem mass spectrometry and mass spectrometry imaging were used in combination with deuterium oxide administration to quantify and localise newly synthesised myelin lipids in the mouse brain. This methodology, used here to show sites of myelin repair, enables the measurement of dynamic lipid synthesis in living systems and ...
Catherine Zhang, Jesse A. Michael, Jonathan D. Teo, Huitong Song, Mika T. Westerhausen, Shadrack M. Mutuku, Shane R. Ellis, Anthony S. Don   +7 more
wiley   +2 more sources

Critique of a Radically New Model for Plasma Membrane Bilayer Organization. [PDF]

Bioessays
Lange Y, Steck TL.
europepmc   +1 more source

Circulating Rhythmic Metabolites and Causal Risk of Type 2 Diabetes in Adults in the Canadian Longitudinal Study on Aging

Diabetes, Obesity and Metabolism, Volume 28, Issue 5, Page 4243-4252, May 2026.
ABSTRACT Aims Circadian regulation of metabolism is an important factor in metabolic health, yet the role of rhythmic metabolites in Type 2 diabetes development remains poorly understood. This study investigated associations between circulating rhythmic metabolites and incident Type 2 diabetes risk and evaluated causal relationships using two‐sample ...
Divya Joshi, Talha Rafiq, Marie Pigeyre, Renee de Mutsert, Femke Rutters, David J.T. Campbell, Jean‐Pierre Despres, Andre C. Carpentier, Joris Hoeks, Patrick Schrauwen, Parminder Raina   +10 more
wiley   +1 more source

The mediating role of immune cells in the effect of plasma lipidome on liver cirrhosis: A Mendelian randomization study. [PDF]

Medicine (Baltimore)
Bai X, Dong X, Sun Q, Yang N, Du L, Zhao L.   +5 more
europepmc   +1 more source

The Ti Plasmid‐Encoded VirJ Functions as a Lysyl‐Phosphatidylglycerol Hydrolase in Agrobacterium tumefaciens

Molecular Microbiology, Volume 125, Issue 5, Page 426-441, May 2026.
We identify the long‐known virulence factor VirJ as a lysyl‐phosphatidylglycerol (L‐PG) hydrolase. Like the chromosomally encoded virulence factor AcvB, it prevents excessive accumulation of L‐PG in the membrane, thereby maintaining efficient T‐DNA transfer via the Type IV secretion system (T4SS) in Agrobacterium tumefaciens.
Britta Lotz, Lina Brodskaia, Christiane Fritz, Stefanie Hebecker, Maike K. Tauchert, Jennifer Breisch, Dieter Jahn, Franz Narberhaus, Jürgen Moser, Meriyem Aktas   +9 more
wiley   +1 more source

Characterization of Milk Fat Globule Membrane Phospholipids in Colostrum of Holstein cows, Yaks and Buffaloes as Well as in Yak Colostrum and Mature Milk. [PDF]

Foods
Luo J, Cao Y, Zhou H, Yan F, Wu S, Zhang H, Fan X.   +6 more
europepmc   +1 more source