Results 191 to 200 of about 105,655 (290)

High‐Density Lipoprotein‐Specific Phospholipid Efflux (HDL‐SPE) Assay in Mice

open access: yesMolecular Nutrition &Food Research, Volume 70, Issue 9, 13 May 2026.
ABSTRACT The recent study by Martínez‐Beamonte et al. provides new insights into how extra virgin olive oil enriched in bioactive compounds may exert anti‐atherogenic effects, by improving high‐density lipoprotein (HDL) function, as determined by the high‐density lipoprotein‐specific phospholipid efflux (HDL‐SPE) assay in Apoe‐deficient mice.
Masaki Sato   +4 more
wiley   +1 more source

Gene Expression Patterns Regulating Peanut Reproductive Phenology

open access: yesPlant Direct, Volume 10, Issue 5, May 2026.
ABSTRACT Peanut reproduction is foundational for crop yield, breeding, and evolution. However, gene regulation underlying peanut flowering pattern and timing has received limited attention. Cultivated peanut (Arachis hypogaea L.) shows two distinct flowering patterns between two subspecies, with ssp.
Carlos Henrique Cardon   +5 more
wiley   +1 more source

Self-Stabilizing Covalent Ligand Targets Bacterial Phosphatidylethanolamine and Enhances Antibiotic Efficacy. [PDF]

open access: yesPharmaceutics
Masuda K   +10 more
europepmc   +1 more source

Proteolytic control of mitochondrial protein translocases

open access: yesProtein Science, Volume 35, Issue 5, May 2026.
Abstract Mitochondria are essential organelles that drive numerous cellular processes, including energy metabolism, ion homeostasis, and programmed cell death. This functional versatility relies on a highly dynamic proteome whose composition is continuously remodeled to meet changing cellular and environmental demands.
Lara Kroczek, Thomas Langer
wiley   +1 more source

Gaining insights into MmpL3: combining structural and computational approaches to unlock transport and inhibitor‐binding mechanisms

open access: yesActa Crystallographica Section D, Volume 82, Issue 5, Page 550-570, May 2026.
This study investigates the mycobacterial membrane protein MmpL3, a key target for new antituberculosis drugs, by combining high‐resolution crystallography and computational simulations. It reveals how the inhibitor UPAR‐1109 binds to MmpL3, providing detailed insights into the function and flexibility of the protein and supporting the rational design ...
Satoshi Murakami   +9 more
wiley   +1 more source

Mitochondrial Homeostasis in Pancreatic β Cell Function: Mechanisms and Therapeutic Targets for Diabetes

open access: yesJournal of Diabetes, Volume 18, Issue 5, May 2026.
This review highlights mitochondrial dysfunction as a central driver of pancreatic β cell failure in diabetes, caused by disrupted mitochondrial quality control (MQC), oxidative stress, and impaired organelle communication. Emerging therapies, such as DRAK2 inhibitors and metabolic reprogramming agents, show promise in restoring β cell function by ...
Ruihan Li   +5 more
wiley   +1 more source

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