Autophagosome marker, LC3, is released extracellularly via several distinct pathways
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito +3 more
wiley +1 more source
Critique of a Radically New Model for Plasma Membrane Bilayer Organization. [PDF]
Lange Y, Steck TL.
europepmc +1 more source
Structural and Functional Characterization of EXPO‐Derived Extracellular Vesicles in Plants
In this study, 3D electron tomography (ET), cryo‐ET, and immunogold transmission electron microscopy (TEM) are employed to characterize plant extracellular vesicles (EVs) under physiological conditions. EVs are classified into three distinct categories according to their size, content, and molecular‐marker profiles. Furthermore, Exo70E2‐positive medium
Jiayang Gao +12 more
wiley +1 more source
The mediating role of immune cells in the effect of plasma lipidome on liver cirrhosis: A Mendelian randomization study. [PDF]
Bai X +5 more
europepmc +1 more source
Pseudomonas aeruginosa utilizes host polyunsaturated phosphatidylethanolamines to trigger theft-ferroptosis in bronchial epithelium [PDF]
Haider H. Dar +29 more
openalex +1 more source
Lipid Droplet‐Localized Spindle Apparatus Coiled‐Coil Protein 1 Regulates Lipid Droplet Distribution
SPDL1‐L, a long isoform of SPDL1, is identified as a bona fide lipid droplet‐associated protein that acts as a dynein adaptor to drive perinuclear clustering of lipid droplets. By linking lipid droplets to the microtubule network, SPDL1‐L extends the function of SPDL1 beyond mitosis and contributes to lipid droplet organization and nuclear remodeling ...
Honggang Su +10 more
wiley +1 more source
Characterization of Milk Fat Globule Membrane Phospholipids in Colostrum of Holstein cows, Yaks and Buffaloes as Well as in Yak Colostrum and Mature Milk. [PDF]
Luo J +6 more
europepmc +1 more source
Comparison of the Effects of Cholesterol or 3β-Hydroxy-5-Oxo-5,6-Secocholestan-6-Al on the Thermotropic and Structural Properties of Mixtures of Phosphatidylethanolamine and Phosphatidylcholine [PDF]
Ellen Wachtel +4 more
openalex +1 more source
The age‐associated disparity of nanocarrier biodistribution limits the nanotherapeutics of childhood solid tumors. This study developed an ultrasound‐activated liposomal prodrug (CSCPTL) to overcome the age‐associated disparity of off‐target distribution.
Danfei Chen +8 more
wiley +1 more source
Polyphasic characterization of Nocardioides aquaegermanicae sp. nov., a novel water-derived actinobacterium. [PDF]
Zhou S +9 more
europepmc +1 more source

