Results 201 to 210 of about 71,224 (296)

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou   +4 more
wiley   +1 more source

Protocol for isolation of lipid droplets and mitochondria from acute myeloid leukemia cells for lipidomic analysis. [PDF]

STAR Protoc
Zhao R, Zhang L, Dong S, Kamachi K, Gupta SK, Akiyama H, Nguyen J, Hackman GL, Andreeff M, Lodi A, Ishizawa J.   +10 more
europepmc   +1 more source

TaBZR1 Directly Activates Autophagy‐Related (ATG) 8 to Promote Wheat Defence to Powdery Mildew

Plant Biotechnology Journal, EarlyView.
Yamei Zhuang, Yongbo Li, Yulian Li, Wang Chen, Ran Han, Xiaolu Wang, Kai Wang, Wenjing Xu, Qingqi Fan, Jianjun Liu, Takao Komatsuda, Huan Chen, Cheng Liu, Guang Qi   +13 more
wiley   +1 more source

Milk Fat Globule Membrane Supplementation Attenuates Cognitive Impairment in APP/PS1 Mice via Suppressing Neuroinflammation in a Gut Microbiota‐Mediated Serum Resolvin D1/Anandamide Manner

Food Frontiers, Volume 7, Issue 2, March 2026.
MFGM modulated gut microbiota accompanied by the increased serum RVD1 and AEA levels, which subsequently regulated the miRNA profile. This modulation alleviated neuroinflammation via suppressing the NLRP3 inflammasome signaling and microglial activation, thereby attenuating AD‐related cognitive impairment both in vivo and in vitro.
Han Gong, Qichen Yuan, Min Du, Xiaohan Liu, Xueying Mao   +4 more
wiley   +1 more source

RNA‐Binding Proteins and Ferroptosis in Cancer: Mechanism and Therapeutic Implications

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Ferroptosis critically influences cancer cell fate and represents a promising therapeutic strategy. Emerging evidence identifies RNA‐binding proteins (RBPs) as key post‐transcriptional regulators of ferroptosis. The figure summarizes ferroptosis‐related RBPs across cancers: blue RBPs act as tumor suppressors by promoting ferroptosis, whereas red RBPs ...
Linlin Chang, Bin Lu, Haotian Shang, Wanjing Ding, Chunhua Wei, Xiaotian Qi, Pengxing He   +6 more
wiley   +1 more source

Several endocannabinoids and amino acids may be biosynthetically converted to catecholamines <i>in vivo</i>. [PDF]

Front Pharmacol
Fitzgerald PJ.
europepmc   +1 more source

Aging‐Derived Alterations in Genomic, Immune, and Metabolic Networks: Implications for Cancer Development and Therapy

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang, Xue Sun, Xinhao Han, Xingda Zhang, Wenzheng Wang, Hongbin Wang, He Ren, Lina Gu   +7 more
wiley   +1 more source

Integrated lipidomics and proteomics analysis in the cardiac surgery-associated acute kidney injury. [PDF]

Ren Fail
Zhou F, Xu Y, Zhang S, Wang L, Zheng X, Ding W, Ma H, Luo Q.   +7 more
europepmc   +1 more source

Human Phosphatidylethanolamine-binding Protein 4 Promotes Transactivation of Estrogen Receptor α (ERα) in Human Cancer Cells by Inhibiting Proteasome-dependent ERα Degradation via Association with Src

, 2010
Haibo Liu, Jianming Qiu, Nan Li, Taoyong Chen, Xuetao Cao   +4 more
openalex   +1 more source

Permeability of 16 Straight‐ and Branched‐Chain Parabens Using the Caco‐2 Assay

Journal of Applied Toxicology, Volume 46, Issue 2, Page 652-668, February 2026.
ABSTRACT The in vitro intestinal permeability of straight‐ and branched‐chain parabens has not been extensively investigated. Sixteen parabens were tested in the Caco‐2 assay. Passive diffusion was measured using PAMPA. The transport of the MCT1 substrate, p‐coumaric acid, as well as propylparaben and isopropylparaben, was investigated.
Nicola J. Hewitt, Manuela Mayer, Andreas Schepky, Corie Ellison   +3 more
wiley   +1 more source