Phospholipid Interconversion and Transport Are Altered in Glaucoma
The FASEB Journal, Volume 40, Issue 2, 31 January 2026.Decreased phosphatidylserine (PS) and increased phosphatidylethanolamine (PE) occur in both trabecular meshwork (TM) cells and aqueous humor due to aberrant phosphatidylserine decarboxylase (PSD) over‐expression, and variation in levels of individual PS or PE species differing by only a few acyl chains occurs due to impaired lipid transport due to ...
Genea Edwards +5 more
wiley +1 more source
Lymphocyte and Granulocyte Phosphatidylethanolamine N-Methyltransferase: Properties and Activity in Cystic Fibrosis [PDF]
Pediatric Research, 1986 Human lymphocyte and granulocyte membranes contain an enzyme, phosphatidylethanolamine N-methyltransferase (PEMT), which catalyzes the transfer of a methyl group from S-adenosylmethionine to the polar head group of phosphatidylethanolamine to form phosphatidylmonomethylethanolamine.
openaire +2 more sources
The Importance of Gut Microbiota on Choline Metabolism in Neurodegenerative Diseases
BiomoleculesThe gut microbiota is a complex ecosystem that influences digestion, immune response, metabolism, and has been linked to health and well-being. Choline is essential for neurotransmitters, lipid transport, cell-membrane signaling, methyl-group metabolism ...
Majid Eslami +8 more
doaj +1 more source
Diversity and Ecological Potentials of Marine Viruses Inhabiting Continental Shelf Seas
Advanced Science, Volume 13, Issue 1, 5 January 2026.To the best of the knowledge, this study provides the largest viral genome dataset from a continental shelf sea. It reveals that over half of vOTUs are novel, highlighting the remarkable viral novelty in the eastern continental shelf seas of China (ECSSC).
Xiaoyue Guo +9 more
wiley +1 more source
Metabolism and Translocation of Aminophospholipids in Mammalian Cells [PDF]
, 2012 In this study we investigated the metabolism, i.e. remodeling and translocation, of the aminophospholipids phosphatidylserine (PS) and phosphatidylethanolamine (PE). A new method for introduction of exogenous PS and PE molecular species to cultured cells
Kainu, Ville
core
A comparative genomics perspective on the genetic content of the alkaliphilic haloarchaeon Natrialba magadii ATCC 43099T [PDF]
, 2012 BACKGROUND: Natrialba magadii is an aerobic chemoorganotrophic member of the Euryarchaeota and is a dual extremophile requiring alkaline conditions and hypersalinity for optimal growth. The genome sequence of Nab.
Diego E Sastre +15 more
core +2 more sources
The Role of Phosphatidylethanolamine N-Methyltransferase (PEMT) and Its Waist-Hip-Ratio-Associated Locus rs4646404 in Obesity-Related Metabolic Traits and Liver Disease. [PDF]
Int J Mol Sci, 2023 Sun C +13 more
europepmc +1 more source
Human ALKBH4 Interacts with Proteins Associated with Transcription [PDF]
, 2015 The Fe(II)- and 2-oxoglutarate (2OG)-dependent dioxygenase AlkB from E. coli is a demethylase which repairs alkyl lesions in DNA, as well as RNA, through a direct reversal mechanism. Humans possess nine AlkB homologs (ALKBH1-8 and FTO). ALKBH2 and ALKBH3
Bjørnstad, Linn +5 more
core +3 more sources
Adenovirus mediated alteration of phosphatidylethanolamine N‐methyltransferase expression in vivo
The FASEB Journal, 2008 Hepatic phosphatidylcholine (PC) is required for normal secretion of VLDL. In all nucleated mammalian cells, PC is synthesized from choline via the Kennedy (CDP‐choline) pathway, and the flux through this pathway is regulated by the activity of CTP: phosphocholine cytidylyltransferase (CT).
Susanne Lingrell +2 more
openaire +1 more source
A proteinaceous organic matrix regulates carbonate mineral production in the marine teleost intestine [PDF]
, 2016 Marine teleost fish produce CaCO(3) in their intestine as part of their osmoregulatory strategy. This precipitation is critical for rehydration and survival of the largest vertebrate group on earth, yet the molecular mechanisms that regulate this ...
Adrian Pelin +6 more
core +2 more sources