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Bovine Parainfluenza Virus Type 3 Infection Reprograms the Bovine Serum Lipidome Associated with Phosphatidylinositol Depletion and Sphingolipid Axis Activation [PDF]
MicroorganismsBovine Parainfluenza Virus Type 3 (BPIV3) is a critical pathogen in the Bovine Respiratory Disease Complex (BRDC), leading to significant economic losses in the cattle industry.
Shubo Wen +6 more
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Regulation of Phosphatidylinositol Synthesis in Human Primordial Placenta [PDF]
BiomoleculesPhosphatidylinositol and its derivatives are essential components of cell membranes and play pivotal roles in growth signaling pathways. In the human primordial placenta, phosphatidylinositol synthesis is catalyzed by phosphatidylinositol synthase (PIS ...
Bence Kovács +10 more
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Inositol metabolism as a broad-spectrum antiviral target [PDF]
Frontiers in MicrobiologyInositol plays many important roles in cellular processes through its various derivatives including phosphatidylinositol phosphates. Viruses use phosphatidylinositol phosphates for their replication in multiple processes including entry, formation of ...
Kunlakanya Jitobaom +3 more
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Role of SEC14-like phosphatidylinositol transfer proteins in membrane identity and dynamics
Frontiers in Plant Science, 2023 Membrane identity and dynamic processes, that act at membrane sites, provide important cues for regulating transport, signal transduction and communication across membranes.
Karolin Montag +3 more
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Biomolecules, 2023 Myo-inositol belongs to one of the sugar alcohol groups known as cyclitols. Phosphatidylinositols are one of the derivatives of Myo-inositol, and constitute important mediators in many intracellular processes such as cell growth, cell differentiation ...
Maria Derkaczew +5 more
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Membranes, 2021 We characterized the size, distribution, and fluidity of microdomains in a lipid bilayer containing phosphatidylinositol (PI) and revealed their roles during the two-dimensional assembly of a membrane deformation protein (FBP17).
Toshinori Motegi +4 more
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Phosphatidylinositol 4-kinases [PDF]
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 1998 Polyphosphoinositides are involved in many signal transduction pathways in eukaryotic cells. The first committed step is catalysed by phosphatidylinositol 4‐kinase leading to the formation of phosphatidylinositol 4‐phosphate. In the last four years, ten cDNA molecules have been cloned which code isoforms of phosphatidylinositol 4‐kinase; some of which ...
T, Gehrmann, L M, Heilmeyer
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Cell Reports, 2021 Summary: Phosphoinositides are important molecules in lipid signaling, membrane identity, and trafficking that are spatiotemporally controlled by factors from both mammalian cells and intracellular pathogens.
Kai Liu +4 more
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Frontiers in Aging Neuroscience, 2022 BackgroundCardiac surgery with cardiopulmonary bypass (CPB) is considered to be one of the surgical types with the highest incidence of post-operative delirium (POD).
He Huang +6 more
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Drosophila Lipase 3 Mediates the Metabolic Response to Starvation and Aging
Frontiers in Aging, 2022 The human LIPA gene encodes for the enzyme lysosomal acid lipase, which hydrolyzes cholesteryl ester and triacylglycerol. Lysosomal acid lipase deficiency results in Wolman disease and cholesteryl ester storage disease.
Lea Hänschke +11 more
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