Results 141 to 150 of about 188,850 (296)

Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands [PDF]

, 1982
Michael J. Berridge, C. Peter Downes, Michael R. Hanley   +2 more
openalex   +1 more source

Lactylation in cancer biology: Unlocking new avenues for research and therapy

Cancer Communications, EarlyView.
Abstract Lactylation, a newly identified post‐translational modification, plays a multifaceted role in cancer biology by integrating epigenetic and non‐epigenetic mechanisms. This review summarizes the latest research progress on lactylation, including its functions in epigenetic regulation and its broader impact on cellular processes.
Xiaoyu Hou, Zhenya Hong, Huimin Zen, Changyi Zhang, Peng Zhang, Ding Ma, Zhiqiang Han   +6 more
wiley   +1 more source

Development and Recent Advances in SLIPT‐PM: A Chemogenetic Platform for Manipulating Signaling at the Plasma Membrane

ChemBioChem, EarlyView.
SLIPT‐PM enables the translocation of tag‐fused proteins from the cytoplasm to the plasma membrane using a synthetic self‐localizing ligand. This user‐friendly system permits reversible control of diverse signaling pathways. This concept article highlights the key features and current applications of SLIPT‐PM as a powerful tool in chemical and ...
Shuya Ohira, Akinobu Nakamura, Kenta Terai, Shinya Tsukiji   +3 more
wiley   +1 more source

Phosphorylation at the Helm: Kinase‐Mediated Regulation of Primary Cilia Assembly and Disassembly

Cytoskeleton, EarlyView.
ABSTRACT The primary cilium serves as an antenna of most vertebrate cells and is important for conveying cues from several signaling pathways into appropriate cellular responses during development and homeostasis. Cilia assembly and disassembly processes are thought to be strictly controlled; however, the precise nature of molecular events underlying ...
Andrea Lacigová, Lukáš Čajánek
wiley   +1 more source

Phosphatidylinositol is involved in the membrane attachment of NCAM-120, the smallest component of the neural cell adhesion molecule. [PDF]

, 1986
Hai‐Tao He, Jacques Barbet, Julie Chaix, Christo Goridis   +3 more
openalex   +1 more source

The Use of Synaptic Extracellular Myo‐Inositol to Treat Developmental and Epileptic Encephalopathy

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Objective The developmental and epileptic encephalopathies (DEE) are associated with serious and lifelong neurological conditions and risk of early mortality. Here, we describe the chronic treatment of a boy with PLCB1‐related DEE with enteral myo‐inositol supplementation as an add‐on therapy to standard antiseizure medications that had been ...
E. Naomi Vos, Didem Demirbas, Lance Rodan, Edward Yang, Sanjay P. Prabhu, Jie Chen, Xiaoping Huang, Wanshu Qi, Robin L. Haynes, Maria K. Lehtinen, Michael J. Bennett, Miao He, Phillip L. Pearl, M. Estela Rubio‐Gozalbo, Annapurna Poduri, Gerard T. Berry   +15 more
wiley   +1 more source

Rapid formation of inositol 1,3,4,5-tetrakisphosphate and inositol 1,3,4-trisphosphate in rat parotid glands may both result indirectly from receptor-stimulated release of inositol 1,4,5-trisphosphate from phosphatidylinositol 4,5-bisphosphate [PDF]

, 1986
Phillip T. Hawkins, Len Stephens, C. Peter Downes   +2 more
openalex   +1 more source

Bio‐Based Solvents Extraction and Enzyme‐assisted Recovery of Furan Fatty Acid From Ammonia‐Stabilized Hevea Latex

European Journal of Lipid Science and Technology, EarlyView.
The latex of Hevea brasiliensis is rich in furan fatty acid (FuFA) esterified in both neutral and polar lipids. Bio‐based solvents to extract FuFA from ammonia‐stabilized latex was tested. Ethyl acetate worked best, especially with low‐ammonia content. Isopropanol was a good alternative. Lipases could also help to efficiently release FuFA. The findings
Chaisiri Kitpaosong, Siriluck Liengprayoon, Tucksin Lerksamran, Kittipong Rattanaporn, Bruno Barea, Achille Marchand, Frédéric Carrière, Hélène Launay, Thongchai Khaeduang, Pisamai Chantuma, Laurent Vaysse, Erwann Durand   +11 more
wiley   +1 more source

Immune cells mediate the association between the plasma lipidome and pancreatic cancer: a Mendelian randomization analysis. [PDF]

Sci Rep
Ma C, Liu D, Ye C, Chen Z, Kong R, Li J, Sun X, Xu Z.   +7 more
europepmc   +1 more source

Effect of L-alpha-phosphatidylinositol on a vascular smooth muscle Ca2+-dependent protease. Reduction of the Ca2+ requirement for autolysis.

, 1984
Sharon A. Coolican, David R. Hathaway
openalex   +1 more source