Results 211 to 220 of about 391,487 (338)

Insulin down-regulates insulin receptor substrate-2 expression through the phosphatidylinositol 3-kinase/Akt pathway [PDF]

open access: bronze, 2003
Yoshiaki Hirashima   +7 more
openalex   +1 more source

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

open access: yesIbrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source

Type Iγ661 Phosphatidylinositol Phosphate Kinase Directly Interacts with AP2 and Regulates Endocytosis [PDF]

open access: hybrid, 2006
Shawn F. Bairstow   +5 more
openalex   +1 more source

Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy

open access: yesIbrain, Volume 11, Issue 1, Page 44-58, Spring 2025.
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley   +1 more source

Export of malaria proteins requires co-translational processing of the PEXEL motif independent of phosphatidylinositol-3-phosphate binding [PDF]

open access: gold, 2016
Justin A. Boddey   +14 more
openalex   +1 more source

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