Results 231 to 240 of about 363,126 (392)

Lipidomics Reveals Common Mechanisms in Polycystic Ovarian Syndrome, Recurrent Spontaneous Abortion, and Infertility: A Genetic-Based Analysis. [PDF]

Int J Womens Health
Tao A, Wu T, Han X, Niu D, Feng X.
europepmc   +1 more source

Phosphatidylserine transport by ORP/Osh proteins is driven by phosphatidylinositol 4-phosphate

Science, 2015
Joachim Moser von Filseck, A. Čopič, V. Delfosse, S. Vanni, C. L. Jackson, W. Bourguet, G. Drin   +6 more
semanticscholar   +1 more source

Impact of Mutational Status on Intracellular Effects of Cell‐Permeable CaaX Peptides in Pancreatic Cancer Cells

ChemBioChem, EarlyView.
This work deals with intracellular effects of cell‐permeable CaaX‐peptides, designed to influence prenylated proteins like KRas. The results show that after CaaX‐1 treatment, not only KRas expression and signaling are specifically altered in mutated pancreatic cancer cells, but also plasma membrane localization of KRas is affected.
Merlin Klußmann, Martin Matijass, Ines Neundorf   +2 more
wiley   +1 more source

Epithelial–mesenchymal transition in development and cancer: role of phosphatidylinositol 3′ kinase/AKT pathways

Oncogene, 2005
L. Larue, A. Bellacosa
semanticscholar   +1 more source

Identification of Natural Killer Cell Enhancers Through Mimicking of the Tumor Microenvironment

Chemistry – A European Journal, Volume 31, Issue 18, March 25, 2025.
The ability of natural killer (NK) cells to identify and eliminate cancer cells is reduced within the tumor microenvironment (TME), allowing cancer to evade detection and eradication by immune cells. We developed a novel co‐culture assay that replicates the immunosuppressive TME conditions to facilitate the discovery of compounds that can prevent NK ...
Aylin Binici, Elisabeth Hennes, Sandra Koska, Jens Alexander Niemann, Alisa Reich, Christiane Pfaff, Sonja Sievers, Astrid Stefanie Kahnt, Dominique Thomas, Slava Ziegler, Carsten Watzl, Herbert Waldmann   +11 more
wiley   +1 more source

Oncogenic role and prognostic significance of PIMREG in melanoma. [PDF]

Transl Cancer Res
Wei X, Jiang Y, Xia T, Du J.
europepmc   +1 more source

Agonist-stimulated phosphatidylinositol-3,4,5-trisphosphate generation by scaffolded phosphoinositide kinases

Nature Cell Biology, 2016
Suyong Choi, Andrew C Hedman, Samar Sayedyahossein, Narendra Thapa, D. Sacks, R. Anderson   +5 more
semanticscholar   +1 more source

Anchoring of membrane proteins via phosphatidylinositol is deficient in two classes of Thy-1 negative mutant lymphoma cells.

, 1986
Andreas Conzelmann, Annalisa Spiazzi, Robert Hyman, Claude Bron   +3 more
openalex   +1 more source

Phosphorylation at the Helm: Kinase‐Mediated Regulation of Primary Cilia Assembly and Disassembly

Cytoskeleton, EarlyView.
ABSTRACT The primary cilium serves as an antenna of most vertebrate cells and is important for conveying cues from several signaling pathways into appropriate cellular responses during development and homeostasis. Cilia assembly and disassembly processes are thought to be strictly controlled; however, the precise nature of molecular events underlying ...
Andrea Lacigová, Lukáš Čajánek
wiley   +1 more source

Phosphatidylinositol promoted the proliferation and invasion of pituitary adenoma cells by regulating POU1F1 expression. [PDF]

Cancer Metab
Xu T, Zhai X, Wang R, Wu X, Zhou Z, Shang M, Wang C, Qi T, Yang W.   +8 more
europepmc   +1 more source