Stimulation of a glycosyl-phosphatidylinositol-specific phospholipase by insulin and the sulfonylurea, glimepiride, in rat adipocytes depends on increased glucose transport [PDF]
, 1994 . Lipoprotein lipase (LPL) and glycolipidanchored cAMP-binding ectoprotein (Gcel) are modified by glycosyl-phosphatidylinositol (GPI) in rat adipocytes, however, the linkage is potentially unstable. Incubation of the cells with either insulin (0.1-30 nM)
Bandlow, Wolfhard +3 more
core +3 more sources
Recognizing Phosphatidylinositol 3-Phosphate [PDF]
Cell, 2001 Phosphatidylinositol 3-phosphate directs the endosomal localization of regulatory proteins by binding to FYVE and PX domains. New structures of these domains complexed with the phosphoinositide headgroup show how interactions with phosphate and hydroxyl groups differentiate this lipid from all others.
James H. Hurley +2 more
openaire +3 more sources
Mboat7 down-regulation by hyper-insulinemia induces fat accumulation in hepatocytes [PDF]
, 2020 BACKGROUND: Naturally occurring variation in Membrane-bound O-acyltransferase domain-containing 7 (MBOAT7), encoding for an enzyme involved in phosphatidylinositol acyl-chain remodelling, has been associated with fatty liver and hepatic disorders.
Davidson, Nicholas O +2 more
core +1 more source
Computational identification of signalling pathways in Plasmodium falciparum [PDF]
, 2011 Malaria is one of the world’s most common and serious diseases causing death of about 3 million people each year. Its most severe occurrence is caused by the protozoan Plasmodium falciparum.
Adebiyi, E. F. +4 more
core +2 more sources
Fatty acid stimulation of membrane phosphatidylinositol hydrolysis by brain phosphatidylinositol phosphodiesterase [PDF]
Biochemical Journal, 1979 The hydrolysis of membrane-bound phosphatidylinositol in rat liver microsomal fraction by the soluble phosphatidylinositol phosphodiesterase from rat brain was markedly stimulated by oleic acid or arachidonic acid. The stimulation did not require added calcium, although it was abolished by EDTA.
A J Letcher +2 more
openaire +3 more sources
Electrodiffusion of Lipids on Membrane Surfaces [PDF]
, 2011 Random lateral translocation of lipids and proteins is a universal process on membrane surfaces. Local aggregation or organization of lipids and proteins can be induced when this lateral random diffusion is mediated by the electrostatic interactions and membrane curvature. Though the lateral diffusion rates of lipids on membrane of various compositions
arxiv +1 more source
Deciphering interplay between Salmonella invasion effectors [PDF]
, 2007 Bacterial pathogens have evolved a specialized type III secretion system (T3SS) to translocate virulence effector proteins directly into eukaryotic target cells.
AL Rozelle +45 more
core +4 more sources
Journal of Biological Chemistry, 1998 Vascular endothelial growth factor (VEGF) has been found to have various functions on endothelial cells, the most prominent of which is the induction of proliferation and differentiation.
H. Gerber +6 more
semanticscholar +1 more source
Cell Reports, 2021 Summary: Phosphoinositides are important molecules in lipid signaling, membrane identity, and trafficking that are spatiotemporally controlled by factors from both mammalian cells and intracellular pathogens.
Kai Liu +4 more
doaj
Phosphatidylinositol synthase and phosphatidylinositol/inositol exchange reactions in turkey erythrocyte membranes [PDF]
Biochemical Journal, 1991 Unlike human erythrocytes, those from avian species, such as turkeys and chicks, rapidly incorporate myo-[3H]inositol into membrane phospholipids. The mechanisms regulating [3H]Ins labelling of phosphatidylinositol have been investigated using turkey erythrocyte membranes.
C P Downes +3 more
openaire +3 more sources