Results 41 to 50 of about 387,101 (335)
Journal of Lipid Research, 2000 Lipid signaling has become a major research area of cell biology and there is a need for methods that accurately and easily measure substrates and products of lipases involved in cell signaling.
Bradley J. Stith +5 more
doaj +1 more source
The multifaceted roles of PI3Kγ in hypertension, vascular biology, and inflammation [PDF]
, 2016 PI3Kγ is a multifaceted protein, crucially involved in cardiovascular and immune systems. Several studies described the biological and physiological functions of this enzyme in the regulation of cardiovascular system, while others stressed its role in ...
Carnevale, Daniela +2 more
core +2 more sources
Do anionic phospholipids serve as cofactors or second messengers for the regulation of activity of cloned ATP-sensitive K+ channels? [PDF]
, 2003 The regulation of ion channels by anionic phospholipids is currently very topical. An outstanding issue is whether phosphatidylinositol 4,5-diphosphate and related species act as true second messengers in signaling or behave in a manner analogous to an ...
Clapp, LH +4 more
core +1 more source
Editorial: Membrane lipids in T cell functions [PDF]
, 2018 Plasma membrane lipids play essential roles in regulating T cell signaling, differentiation, and effector functions. The major lipid species in the plasma membrane are glycerophospholipids, sphingolipids, and sterol lipids.
Tuosto, Loretta, Xu, Chenqi
core +1 more source
Nonomuraea monospora sp. nov., an actinomycete isolated from cave soil in Thailand, and emended description of the genus Nonomuraea [PDF]
, 2012 A novel actinomycete, designated strain PT708T, was isolated from cave soil collected in Pha Tup Cave Forest Park, Nan province, Thailand. It produced compounds with antimicrobial and anticancer activities.
Lumyong, S. +3 more
core +1 more source
Recognizing Phosphatidylinositol 3-Phosphate [PDF]
Cell, 2001 Phosphatidylinositol 3-phosphate directs the endosomal localization of regulatory proteins by binding to FYVE and PX domains. New structures of these domains complexed with the phosphoinositide headgroup show how interactions with phosphate and hydroxyl groups differentiate this lipid from all others.
Misra, Saurav +2 more
openaire +2 more sources
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
A Role for Phosphoinositides in Regulating Plant Nuclear Functions
Frontiers in Plant Science, 2012 Nuclear localized inositol phospholipids and inositol phosphates are important for regulating many essential processes in animal cells such as DNA replication, recombination, RNA processing, mRNA export and cell cycle progression.
Catherine B Dieck +2 more
doaj +1 more source
Identity of Leu-19 (CD56) leukocyte differentiation antigen and neural cell adhesion molecule. [PDF]
, 1989 Neural cell adhesion molecule (N-CAM) is a membrane glycoprotein expressed on neural and muscle tissues that is involved in homotypic adhesive interactions.
Bindl, J +3 more
core +1 more source
Insights into Activation Mechanisms of Store-Operated TRPC1 Channels in Vascular Smooth Muscle. [PDF]
, 2020 In vascular smooth muscle cells (VMSCs), the stimulation of store-operated channels (SOCs) mediate Ca2+ influx pathways which regulate important cellular functions including contraction, proliferation, migration, and growth that are associated with the ...
Albert, AP +3 more
core +1 more source