Results 221 to 230 of about 18,384,661 (291)

Functional phosphoproteomic analysis of SMG1 in nonsense-mediated mRNA decay and DNA damage repair in cancer. [PDF]

Front Syst Biol
Pai AKA, Dcunha L, Gopalakrishnan AP, Ummar S, Rajeev AC, Raju R.   +5 more
europepmc   +1 more source

Mechanisms of Eosinophil Degranulation. [PDF]

Cells
Almas S, Lacy P.
europepmc   +1 more source

Understanding exosomes in diabetic wound healing

Periodontology 2000, EarlyView.
Abstract Background Diabetic wounds signify a major complication of diabetes mellitus, characterized by chronic inflammation, compromised angiogenesis, and high risk of infection, amputation, and mortality. Contemporary therapies remain limited in efficacy and durability.
Paras Ahmad, Yulan Wang, Yufeng Zhang, Anton Sculean, Richard J. Miron   +4 more
wiley   +1 more source

The Crosstalk Between Diabetes and Alzheimer's Disease: A Molecular Perspective. [PDF]

Basic Clin Pharmacol Toxicol
Catakli D, Ozen-Basoglu O, Tuncgovde EB, Ozsarlak-Sozer G.   +3 more
europepmc   +1 more source

Understanding extracellular vesicle biology, isolation, and characterization: The theory of EV‐erything

Periodontology 2000, EarlyView.
Abstract Background Extracellular vesicles (EVs), especially exosomes, are nanoparticles increasingly recognized as key regulators of intercellular communication in both physiological and pathological aspects. Despite rapid progress, inconsistencies in nomenclature, isolation, and characterization continue to restrict translational advancement.
Paras Ahmad, Nima Farshidfar, Nathan E. Estrin, Yulan Wang, Yufeng Zhang, Anton Sculean, Richard J. Miron   +6 more
wiley   +1 more source

A proximity-labeling map of PI5P4K phosphoinositide kinases interaction networks. [PDF]

J Biol Chem
Llorente A, Arora GK, Loughran RM, Murad R, Maurya S, Crabtree S, Portillo B, Chapagain P, Huluka H, Eron S, Goodman K, Ye G, Blind RD, Emerling BM.   +13 more
europepmc   +1 more source

Metabolic reprogramming of the immune response in periodontitis

Periodontology 2000, EarlyView.
Abstract Objective Periodontitis, a highly prevalent chronic inflammatory disease, is characterized by the progressive destruction of the tooth‐supporting tissues, ultimately causing tooth loss. In recent years, the emerging field of immunometabolism has revealed that immune cell function is tightly regulated by intracellular metabolic pathways that ...
Rafael Scaf de Molon, Melissa Grant, Iain Chapple, Joao Paulo Steffens   +3 more
wiley   +1 more source

PI3K/AKT signaling pathway: molecular crossroads in tumorigenesis and therapeutic innovation. [PDF]

Signal Transduct Target Ther
Shi Q, Liu J, Chu Q, Zeng Y, Zhang Y, Jiang S, Yuan X, Zhu D, Li L.   +8 more
europepmc   +1 more source

TMEM16A channel signalling microdomains in the regulation of vascular function

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic representation of TMEM16A channel signalling microdomains. Calcium influx or calcium release from the endoplasmic/sarcoplasmic reticulum (ER/SR) activates TMEM16A channels through interactions with regulatory proteins in vascular smooth muscle cells or endothelial cells. TMEM16A channel activation drives chloride efflux,
Fênix Araujo, Swapnil K. Sonkusare
wiley   +1 more source

Two-step mechanism of Bruton's tyrosine kinase membrane recruitment and activation. [PDF]

Proc Natl Acad Sci U S A
McAllister RA, Stiegler AL, Chari K, Chari M, Bhattacharyya M, Gupta K.   +5 more
europepmc   +1 more source