Results 241 to 250 of about 192,633 (279)

Quantification and Localisation of New Brain Lipid Synthesis Using Deuterium Oxide and High Resolution Mass Spectrometry

Angewandte Chemie, Volume 138, Issue 18, 27 April 2026.
Liquid chromatography tandem mass spectrometry and mass spectrometry imaging were used in combination with deuterium oxide administration to quantify and localise newly synthesised myelin lipids in the mouse brain. This methodology, used here to show sites of myelin repair, enables the measurement of dynamic lipid synthesis in living systems and ...
Catherine Zhang, Jesse A. Michael, Jonathan D. Teo, Huitong Song, Mika T. Westerhausen, Shadrack M. Mutuku, Shane R. Ellis, Anthony S. Don   +7 more
wiley   +2 more sources

Adipose Triglyceride Lipase and Gpr40 Contribute to the Anti‐Contractile Effect of Perivascular Adipose Tissue

Microcirculation, Volume 33, Issue 4, May 2026.
ABSTRACT Objective Perivascular adipose tissue (PVAT) surrounds most peripheral blood vessels and exerts an anti‐contractile influence through paracrine mediators. Although numerous vasoactive factors have been identified, the mechanisms linking adipocyte metabolism to PVAT‐dependent modulation of vascular tone remain poorly defined. Because adipocytes
Miranda Hyatt, Rinaldo Rodrigues Dos Passos, Fenix A. Araujo, Emily W. Wilson, Emily W. Waigi, Tiago J. Costa, Darízy F. Silva, R. Clinton Webb, Camilla F. Wenceslau, Cameron G. McCarthy   +9 more
wiley   +1 more source

Ustilago maydis Phosphatidic Acid and Phosphatidylserine‐Targeting Secreted Lipase Lip3 Is Involved in Pathogenesis

Molecular Plant Pathology, Volume 27, Issue 5, May 2026.
Ustilago maydis secreted lipase, Lip3 targets PA and PS and alkalinises the host apoplast, thus promoting virulence. Loss of Lip3 results in reduced apoplastic pH and decreased pathogenicity. ABSTRACT Lipases constitute important virulence factors. By targeting specific lipids involved in various cellular processes, lipases regulate growth, development,
Anisha Roy, Rituparna Mondal, Anupama Ghosh   +2 more
wiley   +1 more source

The Regulation and Function of Hippo/YAP Pathway in Cancer

The FASEB Journal, Volume 40, Issue 7, 15 April 2026.
Hippo/YAP pathway signaling plays critical roles in the progression of multiple cancer types. This review summarizes current knowledge of Hippo/YAP pathway regulation and function in cancer. We discuss the core components of the Hippo/YAP pathway; its crosstalk with other signaling pathways; regulation by non‐coding RNAs; roles of YAP signaling in ...
Chinmoy Ghosh, Ruchi Kakar, Seline Torkamboor, Yue Sun   +3 more
wiley   +1 more source

ESCRT-0 in Arabidopsis thaliana? Biochemische und zellbiologische Analyse von FYVE2 [PDF]

, 2012
Herberth, Stefanie
core  

NRF2 Stabilization by Isoform-Specific Nuclear Phosphoinositides in Stress Response. [PDF]

Oral Sci Homeost Med
Tang Y, Chen Y, Carrillo ND, Cryns VL, Anderson RA, Sun J, Chen M.   +6 more
europepmc   +1 more source

PIP4K2C: an emerging fulcrum for multiple diseases. [PDF]

Nat Rev Drug Discov
Pozzetti L, Mishra M, Einav S, Asquith CRM.   +3 more
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Type I phosphatidylinositol kinase makes a novel inositol phospholipid, phosphatidylinositol-3-phosphate

Nature, 1988
The generation of second messengers from the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdInsP2) by phosphoinositidase C has been implicated in the mediation of cellular responses to a variety of growth factors and oncogene products. The first step in the production of PtdInsP2 from phosphatidylinositol (PtdIns) is catalysed by PtdIns kinase.
M, Whitman, C P, Downes, M, Keeler, T, Keller, L, Cantley   +4 more
openaire   +4 more sources

General synthesis of phosphatidylinositol 3-phosphates

Tetrahedron Letters, 1995
Uniform synthetic approach to phosphatidylinositol 3-phosphate, 3,4-bisphosphate and 3,4,5-trisphosphate has been elaborated starting from 1D-1-O-tert-butyldiphenylsilyl- and 1,6-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-myo-inositols using regioselective benzoylation at the 3-, 3,4- and 3,4,5-positions of inositol.
Karol S. Bruzik, Robert J. Kubiak
openaire   +1 more source

Intracellular trafficking and turnover of phosphatidylinositol 3-phosphate

Seminars in Cell & Developmental Biology, 2001
Phosphatidylinositol 3-kinases (PI 3-kinases) regulate cellular functions through the 3'-phosphorylation of phosphatidylinositol (PI) and its derivatives. The PI 3-kinase product phosphatidylinositol 3-phosphate [PI(3)P] functions to recruit and activate effector proteins containing FYVE zinc finger domains.
H, Stenmark, D J, Gillooly
openaire   +2 more sources