Results 211 to 220 of about 192,293 (285)
ABSTRACT Inositol pyrophosphates (PP‐InsPs) are central regulators of eukaryotic signaling events. While certain PP‐InsP isomers have been conclusively linked to the regulation of phosphate homeostasis through interaction with SPX domain‐containing proteins in plants, the functions of the recently discovered isomer 4/6‐PP‐InsP5 remain largely unknown ...
Kevin Ritter +10 more
wiley +1 more source
ABSTRACT Background Although epidermal growth factor receptor tyrosine kinase inhibitors (EGFR TKIs) are effective in treating NSCLC with EGFR mutations, the development of resistance limits their long‐term efficacy. Autophagy has been implicated as a potential mechanism behind this acquired resistance.
Yi‐Nan Liu +6 more
wiley +1 more source
Plasma membrane phosphatidylinositol 4-phosphate and 4,5-bisphosphate determine the distribution and function of K-Ras4B but not H-Ras proteins. [PDF]
Gulyás G +6 more
europepmc +1 more source
Intracellular cholesterol transport proteins: roles in health and disease [PDF]
Graham, Annette, Soffientini, Ugo
core +1 more source
Integrated analysis of extraction performance, phospholipid composition, oil quality, and multivariate relationships in green phospholipid recovery from crude rapeseed oil. ABSTRACT Rapeseed oil contains endogenous phospholipids (PLs) and other minor bioactive components, but conventional PL extraction methods commonly rely on chloroform‐based solvent ...
Fangcheng Shao +5 more
wiley +1 more source
EZR-PLC and RhoGTPases interactions in osteosarcoma pathogenesis and metastatic process [PDF]
Leopizzi, Martina
core +1 more source
Interaction between the PH and START domains of ceramide transfer protein competes with phosphatidylinositol 4-phosphate binding by the PH domain. [PDF]
Prashek J +5 more
europepmc +1 more source
Macrophage‐Targeting Biomaterials for Osteoarthritis Therapy
Macrophage‐Targeting Biomaterials for Osteoarthritis Therapy. Created in BioRender. Jain, E. (2026) https://BioRender.com/x4f9o8g. ABSTRACT Osteoarthritis (OA) is a highly prevalent, disabling, and painful disease of the joints, characterized by progressive cartilage degeneration, synovial fibrosis, and pain.
Era Jain, Paul Nana Kwame Sagoe
wiley +1 more source
Spatiotemporal control of phosphatidylinositol 4-phosphate by Sac2 regulates endocytic recycling. [PDF]
Hsu F, Hu F, Mao Y.
europepmc +1 more source
ABSTRACT Lipid metabolism reprogramming is a hallmark of cancer, yet the global lipidome of cancer cells and their extracellular vesicles (EVs) remains poorly understood. Using mass spectrometry, we analyzed the lipid profiles of a panel of human cancer and non‐cancer cell lines along with their secreted EVs.
Noélie Douanne +14 more
wiley +1 more source

