Results 151 to 160 of about 12,824 (233)

TaRIP2 Positively Regulates Wheat Pollen Wall Formation Through MYB80‐Controlled Lipid Metabolism

Plant Biotechnology Journal, Volume 24, Issue 4, Page 2595-2606, April 2026.
ABSTRACT Male‐sterile genes and mutants are critical for hybrid seed production in monocotyledonous crops. Lipids are essential structural components of male reproductive organs, such as the anther and pollen. Here, we show that the pollen‐preferential gene TaRIP2 is essential for wheat anther development and pollen formation. RT‐qPCR analysis revealed
Ran Han, Aifeng Liu, Guang Qi, Chunhao Fang, XiaoLu Wang, Wenjing Xu, Kai Wang, Jihu Li, Qingqi Fan, Dungong Cheng, Faji Li, Haosheng Li, Jianjun Liu, Genying Li, Cheng Liu   +14 more
wiley   +1 more source

Linking Superoxide Production and Scavenging in Plant Development

Plant, Cell &Environment, Volume 49, Issue 4, Page 2048-2068, April 2026.
ABSTRACT Due to their strong oxidizing potential, rapid membrane permeability, and high reactivity, reactive oxygen species (ROS) play essential roles in plant development and stress responses. Superoxide (O2•‐) is a primary product of molecular oxygen reduction and a crucial source of hydrogen peroxide, representing a ROS species of substantial ...
Jan Řehák, Maryna Tsinyk, Petr Dvořák, Tomáš Takáč   +3 more
wiley   +1 more source

Phosphoinositide 3-kinase δ activity in patients with systemic lupus erythematosus. [PDF]

Front Immunol
Mirfazeli ES, Kharkar S, Tsang-A-Sjoe MWP, Papapietro O, Niewczas I, Parra Sanchez AR, Chandra A, Okkenhaug K, Bultink IEM, Mebius RE, Clark J, Voskuyl AE, Nejentsev S.   +12 more
europepmc   +1 more source

Quinic Acid and Synthetic Derivatives in Medicinal Chemistry

ChemMedChem, Volume 21, Issue 5, 13 March 2026.
Quinic acid and its derivatives are gaining recognition as versatile scaffolds in drug discovery. This review explores their emerging roles in inflammation, infection, cancer, and metabolic disorders, highlighting recent advances that position them beyond chlorogenic acids as promising platforms for therapeutic innovation. Quinic acid (QA) is a natural
Iago C. Vogel, Manuel J. Verganista, Nuno R. Candeias   +2 more
wiley   +1 more source

Inositol and PIP2/PIP3 Ratio: At the Crossroad of the Biodynamic Interface Between Cells and Their Microenvironment. [PDF]

Biomolecules
Lentini G, Querqui A, Giuliani A, Verna R, Bizzarri M.   +4 more
europepmc   +1 more source

Laurdan: Clarifying Photophysics and Advancing the Characterization of Extracellular Vesicles

ChemPhysChem, Volume 27, Issue 5, 13 March 2026.
Biophysical properties of extracellular vesicles (EVs) reflect their composition and membrane organization. We introduce a novel approach using time‐resolved emission spectra (TRES) phasor analysis of the polarity‐sensitive probe Laurdan to characterize membranes with complex compositions.
Petra Riegerová, Mariana Amaro, Peter Kapusta, Antonín Vlček, Martin Smolko, Karel Souček, Vendula Pospíchalová, Martin Hof, Šárka Pokorná   +8 more
wiley   +1 more source

Phosphatidylinositol 3-phosphate metabolism impacts cellular α-synuclein localization in Saccharomyces cerevisiae. [PDF]

J Biol Chem
Löser T, Bekbulat F, Behl C, Schepers J.   +3 more
europepmc   +1 more source

Irreversible platelet activation requires protease-activated receptor 1-mediated signaling to phosphatidylinositol phosphates. [PDF]

Mol Pharmacol, 2009
Holinstat M, Preininger AM, Milne SB, Hudson WJ, Brown HA, Hamm HE.   +5 more
europepmc   +1 more source

Systematic analyses of lipid mobilization by human lipid transfer proteins. [PDF]

Nature
Titeca K, Chiapparino A, Hennrich ML, Türei D, Moqadam M, Talandashti R, Cuveillier C, van Ek L, Zukowska J, Triana S, Echelard F, Nielsen IØ, Foged MM, Gehin C, Olechnovic K, Grudinin S, Saez-Rodriguez J, Alexandrov T, Maeda K, Reuter N, Gavin AC.   +20 more
europepmc   +1 more source

A computational framework for the investigation of phosphoinositide regulation. [PDF]

PLoS Comput Biol
Cheung HYF, Tantiwong C, Kale D, Gibbins JM, Watson SP, Heemskerk JWM, Sickmann A, Ahrends R, Dunster JL.   +8 more
europepmc   +1 more source