The Inositol- 1,4,5=Trisphosphate System Is Involved in Rapid Effects of Aldosterone in Human Mononuclear Leukocytes [PDF]
, 1993 There is increasing evidence for rapid steroid action on electrolyte transport in human mononuclear leukocytes (HML). In HML, aldosterone stimulates the Na+/H+ antiporter within a few minutes. Because a variety of hormones and growth factors activate the
Aktas, Janet +4 more
core +1 more source
Association of phosphatidylinositol kinase and phosphatidylinositol 4‐phosphate kinase activities with the cytoskeleton in human platelets [PDF]
, 1989 Nabeel Nahas +3 more
openalex +1 more source
Synthesis and evaluation of receptors for phosphatidylinositol phosphates
, 2013 Phosphatidylinositol phosphates (PIPs) are signalling phospholipids with a diverse set of cellular functions. The most important of these PIPs are phosphatidylinositol (4,5) bisphosphate (PI(4,5)P2) and phosphatidylinositol (3,4,5) trisphosphate (PI(3,4,5)P3).
openaire +4 more sources
Journal of Orthopaedic Research, EarlyView.ABSTRACT Posttraumatic osteoarthritis (PTOA) is a common sequela to anterior cruciate ligament (ACL) injury in humans and dogs. Identification of conserved targets between species may hasten biomarker identification and therapeutic development. To identify differentially regulated synovial fluid (SF) proteins in ACL injury, SF samples were collected ...
Sydney J. Womack +4 more
wiley +1 more source
Structural and dynamic changes in P-Rex1 upon activation by PIP3 and inhibition by IP4
eLifePIP3-dependent Rac exchanger 1 (P-Rex1) is abundantly expressed in neutrophils and plays central roles in chemotaxis and cancer metastasis by serving as a guanine-nucleotide exchange factor (GEF) for Rac.
Sandeep K Ravala +7 more
doaj +1 more source
Dynamics of ion-phosphate lattice of DNA in left-handed double helix form [PDF]
Ukr. J. Phys. V. 58, 554-562 (2013), 2013 The conformational vibrations of Z-DNA with counterions are studied in framework of phenomenological model developed. The structure of left-handed double helix with counterions neutralizing the negatively charged phosphate groups of DNA is considered as the ion-phosphate lattice. The frequencies and Raman intensities for the modes of Z-DNA with Na+ and
arxiv
Psoralen and ultraviolet A light treatment directly affects phosphatidylinositol 3-kinase signal transduction by altering plasma membrane packing [PDF]
, 2016 Psoralen and ultraviolet A light (PUNTA) are used to kill pathogens in blood products and as a treatment of aberrant cell proliferation in dermatitis, cutaneous T-cell lymphoma, and graft versus-host disease.
Compernolle, Veerle +7 more
core +2 more sources
Purification of a Phosphatidylinositol 4‐Phosphate Kinase from Bovine Brain Membranes [PDF]
, 1990 Albrecht Moritz +4 more
openalex +1 more source
Self‐Assembly of Noncanonical Peptides: A New Frontier in Cancer Therapeutics and Beyond
Macromolecular Bioscience, EarlyView.Representative examples of noncanonical peptide assemblies in anticancer therapeutics, biomaterials, regenerative medicine, molecular imaging, and catalysis are discussed, highlighting enzyme‐instructed self‐assembly as a valuable approach for constructing biomimetic and bioinspired materials that bridge the interface between biological systems and ...
Lin Bai, Meihui Yi, Bing Xu
wiley +1 more source
Synergistic Role of Transition Metals and Polyanionic Frameworks in Phosphate-Based Cathode Materials for Sodium-Ion Batteries [PDF]
arXivOngoing research in the area of advanced cathode materials for sodium-ion batteries (SIBs) is expected to reduce reliance on lithium-ion batteries (LIBs), providing more affordable and sustainable energy storage solutions. Polyanionic compounds have emerged as promising options due to their stable structure and ability to withstand high-voltage ...
arxiv