Results 191 to 200 of about 13,924 (256)

Irreversible platelet activation requires protease-activated receptor 1-mediated signaling to phosphatidylinositol phosphates. [PDF]

Mol Pharmacol, 2009
Holinstat M, Preininger AM, Milne SB, Hudson WJ, Brown HA, Hamm HE.   +5 more
europepmc   +1 more source

CERKL Reduced PI3P/Autophagy to Promote Pancreatic Cancer. [PDF]

Cancer Med
Zeng W, Yang Y, Li W, Pan J, Huang B, Zhang P, Xiao J.   +6 more
europepmc   +1 more source

Hypoxia and the cytoskeleton

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the activation of hypoxia‐sensitive pathways, the influence of hypoxia and associated pathways on the cytoskeleton, and the impact of these on disease progression. Abstract A highly‐regulated and dynamic cytoskeleton is vital for functional cellular physiology and the maintenance of homeostasis.
Darragh Flood, Cormac T. Taylor
wiley   +1 more source

From Obscurity to Prominence: IPMK's Expanding Role in Cellular Signaling, Physiology, and Disease. [PDF]

Biomolecules
Mishra SH, Chatterjee S, Viera-Preval L, Guha P.   +3 more
europepmc   +1 more source

Aging‐Derived Alterations in Genomic, Immune, and Metabolic Networks: Implications for Cancer Development and Therapy

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang, Xue Sun, Xinhao Han, Xingda Zhang, Wenzheng Wang, Hongbin Wang, He Ren, Lina Gu   +7 more
wiley   +1 more source

MicroRNA analysis of porcine muscle tissue involved in phosphoinositol metabolism. [PDF]

Front Vet Sci
Xie Y, Cheng W, Hao M, Yi LL, Zhu JH, Zhao YG, Zhao S.   +6 more
europepmc   +1 more source

A serum factor that activates the phosphatidylinositol phosphate signaling system in Xenopus oocytes.

, 1990
Gábor Tigyi, David L. Dyer, Carlos Matute, Ricardo Miledi   +3 more
openalex   +2 more sources

Unraveling Lysosomal Exocytosis: From Molecular Mechanisms to Physiological Functions

Traffic, Volume 27, Issue 1, March 2026.
Lysosomal exocytosis is propelled by specific molecular mechanisms that direct its microtubule‐dependent transport and subsequent fusion with the plasma membrane. This process fulfills essential physiological functions such as plasma membrane repair, maintenance of cellular homeostasis, and participation in signal transduction.
Shanshan Jiang, Jingyi Fu, Shan Li, Zehui Li, Qirui Zhao, Yuqi Yin, Mei Yang, Yonghua Wang   +7 more
wiley   +1 more source

Nitric oxide attenuates PI4P accumulation at the ER membrane to inhibit encephalomyocarditis virus replication selectively in β-cells. [PDF]

J Biol Chem
Gehant AL, Stafford JD, Hansen PA, Harty KR, Naatz A, Corbett JA.   +5 more
europepmc   +1 more source

Climate change and the antinutrient–antioxidant puzzle in common bean seeds

Journal of the Science of Food and Agriculture, Volume 106, Issue 3, Page 1451-1456, February 2026.
Abstract Non‐proteinaceous and proteinaceous antinutrients in common bean (Phaseolus vulgaris L.) seeds can negatively affect human nutrition by reducing mineral bioavailability and impairing protein digestibility during digestion, respectively. However, many of these compounds also possess strong antioxidant properties that can help protect the plant ...
Juan Vorster, Eleonora Cominelli, Francesca Sparvoli, Alessia Losa, Tea Sala, Karl Kunert   +5 more
wiley   +1 more source