Results 191 to 200 of about 12,824 (233)

The phosphatidylinositol 4-phosphate 5-kinase family

Advances in Enzyme Regulation, 1996
The existence of a PIP5K family of enzymes has been suggested by Western blotting and purification of numerous PIP5Ks from various tissues and cell types. The erythrocyte has at least two PIP5Ks, named PIP5KI and PIP5KII, while the brain appears to have even more isoforms.
J C, Loijens, I V, Boronenkov, G J, Parker, R A, Anderson   +3 more
openaire   +2 more sources

General Synthesis of Phosphatidylinositol Phosphates

Phosphorus, Sulfur, and Silicon and the Related Elements, 1996
Abstract A general method for synthesis of 3-phosphorylated phosphatidylinositols is described. Phosphatidylinositol (PI) and phosphatidylinositol phosphates (PIPn), such as PI-4-P, PI-4,5-P2 undergo receptor-mediated cleavage by phosphatidylinositol-specific phospholipase C, and are precursors of second messengers important in diverse cellular ...
Robert Kubiak, Karol Bruzik
openaire   +1 more source

Phox Homology Domains Specifically Bind Phosphatidylinositol Phosphates

Biochemistry, 2001
The recruitment of specific cytosolic proteins to intracellular membranes through binding phosphorylated derivatives of phosphatidylinositol (PtdIns) controls such processes as endocytosis, regulated exocytosis, cytoskeletal organization, and cell signaling.
X, Song, W, Xu, A, Zhang, G, Huang, X, Liang, J V, Virbasius, M P, Czech, G W, Zhou   +7 more
openaire   +2 more sources

Type I phosphatidylinositol kinase makes a novel inositol phospholipid, phosphatidylinositol-3-phosphate

Nature, 1988
The generation of second messengers from the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdInsP2) by phosphoinositidase C has been implicated in the mediation of cellular responses to a variety of growth factors and oncogene products. The first step in the production of PtdInsP2 from phosphatidylinositol (PtdIns) is catalysed by PtdIns kinase.
M, Whitman, C P, Downes, M, Keeler, T, Keller, L, Cantley   +4 more
openaire   +2 more sources

Inhibition of phosphatidylinositol-4-phosphate kinase by its product phosphatidylinositol-4,5-bisphosphate

Biochemical and Biophysical Research Communications, 1985
Phosphatidylinositol 4,5-bisphosphate (PIP2) is enzymatically produced when high speed supernatant fraction from bovine retina is incubated with [gamma-32P]ATP and phosphatidylinositol 4-phosphate (PIP) as substrates. Exogenously added PIP2 inhibits PIP kinase activity 50% at equimolar concentrations of product and substrate.
L A, Van Rooijen, M, Rossowska, N G, Bazan   +2 more
openaire   +2 more sources

ChemInform Abstract: Synthesis of Phosphatidylinositol Phosphates

ChemInform, 1997
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
T. DESAI, J. GIGG, R. GIGG, E. MARTIN‐ZAMORA   +3 more
openaire   +1 more source

Nuclear Phosphatidylinositol Signaling: Focus on Phosphatidylinositol Phosphate Kinases and Phospholipases C.

Journal of cellular physiology, 2016
Phosphatidylinositol (PI) metabolism represents the core of a network of signaling pathways which modulate many cellular functions including cell proliferation, cell differentiation, apoptosis, and membrane trafficking. An array of kinases, phosphatases, and lipases acts on PI creating an important number of second messengers involved in different ...
POLI, ALESSANDRO, BILLI, ANNA MARIA, MONGIORGI, SARA, RATTI, STEFANO, Mccubrey, James A., Suh, Pann Ghill, COCCO, LUCIO ILDEBRANDO, RAMAZZOTTI, GIULIA   +7 more
openaire   +3 more sources

Review of Phosphatidylinositol Phosphate Kinase in Phosphatidylinositol Signaling Pathway

2014
Phosphatidylinositol signaling pathway is an important signal transduction pathway that plays critical roles in multiple cell processes first demonstrated in animal cells. Research evidences have shown that although not exactly the same as it is in yeast and mammalian cells, phosphatidylinositol signaling pathway also exists in plant cells and is ...
openaire   +1 more source

Phosphatidylinositol-3-phosphate and inositol phosphates in mitogenesis

Biochemical Society Transactions, 1990
D, Poyner, P, Hawkins, M, Hanley
openaire   +2 more sources

A comprehensive survey on nonlinear optical phosphates: Role of multicoordinate groups

Coordination Chemistry Reviews, 2021
Dajiang Mei, Zhe-Shuai Lin
exaly