Results 211 to 220 of about 837,784 (254)

Phosphatidylinositol-3-phosphate and inositol phosphates in mitogenesis

Biochemical Society Transactions, 1990
Phillip Hawkins
exaly   +3 more sources

Asymmetric Syntheses of Phosphatidylinositol-3-Phosphates with Saturated and Unsaturated Side Chains through Catalytic Asymmetric Phosphorylation

Journal of the American Chemical Society, 2004
Bianca Sculimbrene, Scott J Miller, Scott J Miller*   +2 more
exaly   +2 more sources

Phosphatidylinositol phosphates

Laboratory Techniques in Biochemistry and Molecular Biology / Edited By T S Work [and] E Work, 2003
exaly   +2 more sources

General synthesis of phosphatidylinositol 3-phosphates

Tetrahedron Letters, 1995
Karol S Bruzik
exaly   +2 more sources

Phosphatidylinositol and inositol phosphate metabolism

Journal of Cell Science, 2001
The six carbons that comprise the inositol ring can be phosphorylated in a combinatorial manner, generating a truly astonishing range of inositol phosphates and inositol lipids. Yet, somehow, the cell can distinguish and utilize several of these metabolites to specifically regulate a variety ...
K, Abel, R A, Anderson, S B, Shears
openaire   +2 more sources

Phosphatidylinositol‐4‐phosphate: The Golgi and beyond

BioEssays, 2013
Initially identified as a key phosphoinositide that controls membrane trafficking at the Golgi complex, phosphatidylinositol‐4‐phosphate (PI4P) has emerged as a key molecule in the regulation of a diverse array of cellular functions. In this review we will discuss selected examples of the findings that in the last few years have significantly increased
DE MATTEIS, Maria Antonietta, Wilson, Cathal, D'Angelo, Giovanni   +2 more
openaire   +3 more sources

Phosphatidylinositol 4-kinases, phosphatidylinositol 4-phosphate and cancer

Cancer Letters, 2012
This article focuses on the emerging roles for phosphatidylinositol 4-phosphate and the phosphatidylinositol 4-kinases in cancer. Phosphatidylinositol 4-phosphate is a common substrate for both the phosphatidylinositol 3-kinase and phospholipase C pathways, and has been implicated in the membrane targeting of proteins such as Girdin/GIV and OSBP ...
openaire   +2 more sources

Phosphatidylinositol phosphate kinases.

Journal of endocrinological investigation, 2004
Phosphatidylinositol 4,5-bisphosphate is a multi-functional lipid, whose proposed functions now number more than twenty, covering many aspects of cell biology in several different subcellular compartments. The enzymes primarily responsible for synthesizing this lipid, the Type I phosphatidylinositol 4-phosphate 5-kinases, are therefore a tightly ...
Giudici, ML, Hinchliffe, KA, Irvine, RF
openaire   +2 more sources

Phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate: Lipids in search of a function

Cell Calcium, 1982
Recent years have seen a rapid accumulation of information which relates to the idea that receptor-controlled effects on inositol lipid metabolism might somehow be involved in the control of stimulated cells (see refs 1–14 for reviews). Most of these studies have been concerned only with phosphatidylinositol (PtdIns) and have tended to ignore the ...
P, Downes, R H, Michell
openaire   +2 more sources

Characterization of phosphatidylinositol and phosphatidylinositol-4-phosphate kinases in human neutrophils.

The Journal of Immunology, 1988
Abstract Phosphodiesteric cleavage of phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) is required for transmembrane signaling by chemoattractants in human polymorphonuclear leukocytes (PMN). Considering the importance of PtdIns-4,5-P2 as a reservoir for second messenger substances, we have characterized the enzyme system that ...
M C, Pike, C, Arndt
openaire   +2 more sources