Results 161 to 170 of about 77,486 (386)

Phosphatidylinositol kinase. A component of the chromaffin-granule membrane [PDF]

, 1973
John H. Phillips
openalex   +1 more source

Trapped ion mobility spectrometry and PASEF enable in-depth lipidomics from minimal sample amounts

, 2020
A comprehensive characterization of the lipidome from limited starting material remains very challenging. Here we report a high-sensitivity lipidomics workflow based on nanoflow liquid chromatography and trapped ion mobility spectrometry (TIMS).
Barsch, A., Brunner, A., Mann, M., Meier, F., Meitei, N., Meyer, S., Schweiger-Hufnagel, U., Sulek, K., Vasilopoulou, C.   +8 more
core   +1 more source

RUNX1/SLAMF3 Axis Drives Immunosuppression to Contribute to Colorectal Cancer Liver Metastasis by Blocking Phagocytosis and Depleting C1QC+ Tumor‐Associated Macrophages

Advanced Science, EarlyView.
This study identifies the RUNX1/SLAMF3 axis as a key driver of colorectal cancer liver metastasis (CRLM). SLAMF3 suppresses macrophage phagocytosis and depletes C1QC⁺ tumor‐associated macrophages, promoting an immunosuppressive microenvironment. Targeting this axis restores macrophage and CD8⁺ T cell activity and reduces metastasis.
Yinheng Luo, Xiaoli Jin, Lan Huang, Dejia Zeng, Nan Zhang, Shiyu Tang, Shu Luo, Samina Ejaz Syed, Ruiwu Dai, Qiu Li, Shufang Liang   +10 more
wiley   +1 more source

Phosphatidylinositol cleavage catalysed by the soluble fraction from lymphocytes. Activity at pH5.5 and pH7.0 [PDF]

, 1974
David Allan, Robert H. Michell
openalex   +1 more source

Lipidomics analysis reveals new insights into the goose fatty liver formation

Poultry Science, 2023
: Our previous study described the mechanism of goose fatty liver formation from cell culture and transcriptome. However, how lipidome of goose liver response to overfeeding is unclear.
Rongxue Wei, Rong Ning, Chunchun Han, Shouhai Wei, Yongqiang Teng, Liang Li, Hehe Liu, Shengqiang Hu, Bo Kang, Hengyong Xu   +9 more
doaj  

Advecting Scaffolds: Controlling The Remodelling Of Actomyosin With Anillin [PDF]

arXiv
We propose and analyse an active hydrodynamic theory that characterises the effects of the scaffold protein anillin. Anillin is found at major sites of cortical activity, such as adherens junctions and the cytokinetic furrow, where the canonical regulator of actomyosin remodelling is the small GTPase, RhoA.
arxiv  

Effects of calcium-antagonistic drugs on the stimulation by carbamoylcholine and histamine of phosphatidylinositol turnover in longitudinal smooth muscle of guinea-pig ileum [PDF]

, 1976
SHAMSHAD S. JAFFERJI, Robert H. Michell
openalex   +1 more source

Spatial and temporal alterations of phospholipids determined by mass spectrometry during mouse embryo implantation[S]

Journal of Lipid Research, 2009
Molecular events involved in successful embryo implantation are not well understood. In this study, we used MALDI imaging mass spectrometry (IMS) technologies to characterize the spatial and temporal distribution of phospholipid species associated with ...
Kristin E. Burnum, Dale S. Cornett, Satu M. Puolitaival, Stephen B. Milne, David S. Myers, Susanne Tranguch, H. Alex Brown, Sudhansu K. Dey, Richard M. Caprioli   +8 more
doaj  

Short-term exposure to antimony induces hepatotoxicity and metabolic remodeling in rats

Ecotoxicology and Environmental Safety, 2023
Antimony (Sb) poses a significant threat to human health due to sharp increases in its exploitation and application globally, but few studies have explored the pathophysiological mechanisms of acute hepatotoxicity induced by Sb exposure.
Wen Gu, Ruifang Pang, Yuanyuan Chen, Fuchang Deng, Miao Zhang, Zijin Shao, Shuyi Zhang, Huawei Duan, Song Tang   +8 more
doaj  

Enhanced phosphatidylinositol labelling in rat parotid fragments exposed to α-adrenergic stimulation [PDF]

, 1974
Robert H. Michell, Lynne Jones
openalex   +1 more source