Results 51 to 60 of about 108,878 (236)

Scrambled Eggs: Apoptotic cell clearance by non-professional phagocytes in the Drosophila ovary [PDF]

open access: yes, 2017
This manuscript was supported by NIH grant R01 GM060574 to KM.
McCall, Kimberly, Serizier, Sandy B.
core   +1 more source

Carmustine-Induced Phosphatidylserine Translocation in the Erythrocyte Membrane

open access: yesToxins, 2013
The nitrosourea alkylating agent, carmustine, is used as chemotherapeutic drug in several malignancies. The substance triggers tumor cell apoptosis. Side effects of carmustine include myelotoxicity with anemia.
Kashif Jilani, Florian Lang
doaj   +1 more source

Breakdown of Phospholipid Asymmetry Triggers ADAM17-Mediated Rescue Events in Cells Undergoing Apoptosis

open access: yesMembranes, 2023
ADAM17, a prominent member of the “Disintegrin and Metalloproteinase” (ADAM) family, controls vital cellular functions through the cleavage of transmembrane substrates, including epidermal growth factor receptor (EGFR) ligands such as transforming growth
Maria Sperrhacke   +3 more
doaj   +1 more source

Heterotrimeric G-protein subunit Gαi2 contributes to agonist-sensitive apoptosis and degranulation in murine platelets [PDF]

open access: yes, 2018
Gαi2, a heterotrimeric G-protein subunit, regulates various cell functions including ion channel activity, cell differentiation, proliferation and apoptosis.
Birnbaumer, Lutz   +12 more
core   +1 more source

Induction of Suicidal Erythrocyte Death by Cantharidin

open access: yesToxins, 2015
The natural phosphoprotein phosphatase inhibitor cantharidin, primarily used for topical treatment of warts, has later been shown to trigger tumor cell apoptosis and is thus considered for the treatment of malignancy. Similar to apoptosis of tumor cells,
Kousi Alzoubi   +5 more
doaj   +1 more source

Optimization of Sentinel Lymph Node Imaging Methodology Using Anionic Liposome and Hyaluronidase

open access: yesPharmaceutics, 2021
The sentinel lymph node (SLN) is the first lymph node into which lymphatic fluid from tumor tissues flows. The development of a highly sensitive probe for detecting SLNs is desired for the lymph node dissection through intraoperative biopsy.
Yu Sakurai   +4 more
doaj   +1 more source

Phosphatidylserine dynamics in cellular membranes [PDF]

open access: yesMolecular Biology of the Cell, 2012
Much has been learned about the role of exofacial phosphatidylserine (PS) in apoptosis and blood clotting using annexin V. However, because annexins are impermeant and unable to bind PS at low calcium concentration, they are unsuitable for intracellular use. Thus little is known about the topology and dynamics of PS in the endomembranes of normal cells.
Kay, J.G.   +4 more
openaire   +2 more sources

Induction of Suicidal Erythrocyte Death by Nelfinavir

open access: yesToxins, 2015
The HIV protease inhibitor, nelfinavir, primarily used for the treatment of HIV infections, has later been shown to be effective in various infectious diseases including malaria. Nelfinavir may trigger mitochondria-independent cell death.
Rosi Bissinger   +2 more
doaj   +1 more source

Molecular Electroporation and the Transduction of Oligoarginines

open access: yes, 2009
Certain short polycations, such as TAT and polyarginine, rapidly pass through the plasma membranes of mammalian cells by an unknown mechanism called transduction as well as by endocytosis and macropinocytosis.
Alberts B   +20 more
core   +1 more source

Theory of Lipid Polymorphism: Application to Phosphatidylethanolamine and Phosphatidylserine [PDF]

open access: yes, 1999
We introduce a microscopic model of a lipid with a charged headgroup and flexible hydrophobic tails, a neutral solvent, and counter ions. Short-ranged interactions between hydrophilic and hydrophobic moieties are included as are the Coulomb interactions ...
Ben-Shaul   +43 more
core   +3 more sources

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