Results 51 to 60 of about 133,958 (282)
Use of autoantigen-loaded phosphatidylserine-liposomes to arrest autoimmunity in type 1 diabetes [PDF]
, 2015 This is an open access article distributed under the terms of the Creative Commons Attribution License.-- et al.[Introduction]: The development of new therapies to induce self-tolerance has been an important medical health challenge in type 1 diabetes ...
Cano-Sarabia, Mary +3 more
core +4 more sources
Molecular Therapy: Methods & Clinical Development, 2023 Adoptive therapy with genetically engineered T cells offers potential for infectious disease treatment in immunocompromised persons. HIV/simian immunodeficiency virus (SIV)-infected cells express phosphatidylserine (PS) early post infection.
Daniel Corey +3 more
doaj +1 more source
Influenza A matrix protein M1 induces lipid membrane deformation via protein multimerization [PDF]
, 2019 The matrix protein M1 of the Influenza A virus (IAV) is supposed to mediate viral assembly and budding at the plasma membrane (PM) of infected cells. In order for a new viral particle to form, the PM lipid bilayer has to bend into a vesicle toward the ...
Chiantia, Salvatore +2 more
core +1 more source
Stabilin Receptors: Role as Phosphatidylserine Receptors
Biomolecules, 2019 Phosphatidylserine is a membrane phospholipid that is localized to the inner leaflet of the plasma membrane. Phosphatidylserine externalization to the outer leaflet of the plasma membrane is an important signal for various physiological processes ...
Seung-Yoon Park, In-San Kim
doaj +1 more source
7-Keto-Cholesterol and Cholestan-3beta, 5alpha, 6beta-Triol Induce Eryptosis through Distinct Pathways Leading to NADPH Oxidase and Nitric Oxide Synthase Activation [PDF]
, 2019 BACKGROUND/AIMS: We showed that patho-physiological concentrations of either 7-keto-cholesterol (7-KC), or cholestane-3beta, 5alpha, 6beta-triol (TRIOL) caused the eryptotic death of human red blood cells (RBC), strictly dependent on the early production
Allegra M. +5 more
core +1 more source
Nanoelectropulse-Induced Phosphatidylserine Translocation [PDF]
Biophysical Journal, 2004 Nanosecond, megavolt-per-meter, pulsed electric fields induce phosphatidylserine (PS) externalization, intracellular calcium redistribution, and apoptosis in Jurkat T-lymphoblasts, without causing immediately apparent physical damage to the cells. Intracellular calcium mobilization occurs within milliseconds of pulse exposure, and membrane phospholipid
Thomas Vernier, P. +4 more
openaire +2 more sources
EMBO Journal, 2021 Synaptic refinement is a critical physiological process that removes excess synapses to establish and maintain functional neuronal circuits. Recent studies have shown that focal exposure of phosphatidylserine (PS) on synapses acts as an “eat me” signal ...
Tao Li +8 more
semanticscholar +1 more source
Programmed cell death of platelets during their overactivation
Онкогематология, 2015 Programmed cell death – it is a cell death by a strictly defined mechanism with possible impact on him and, due to this, the death control, including using of pharmacological agents.
E. O. Artemenko +2 more
doaj +3 more sources
Annexin-A5 assembled into two-dimensional arrays promotes cell membrane repair [PDF]
, 2011 Eukaryotic cells possess a universal repair machinery that ensures rapid resealing of plasma membrane disruptions. Before resealing, the torn membrane is submitted to considerable tension, which functions to expand the disruption.
A Brisson +56 more
core +2 more sources
Proceedings of the National Academy of Sciences of the United States of America, 2020 Significance Feedback control of cholesterol metabolism is essential for cell viability and prevention of heart attacks. Cells acquire cholesterol from receptor-mediated uptake of low-density lipoprotein, which delivers cholesterol to lysosomes. To exert
M. N. Trinh +8 more
semanticscholar +1 more source