Results 71 to 80 of about 133,958 (282)

Vitamin C inhibits endothelial cell apoptosis in congestive heart failure [PDF]

, 2007
Background - Proinflammatory cytokines like tumor necrosis factor- and oxidative stress induce apoptotic cell death in endothelial cells (ECs). Systemic inflammation and increased oxidative stress in congestive heart failure (CHF) coincide with enhanced ...
Aicher, A, Dimmeler, S, Freyssinet, JM, Haase, A, Hoffmann, J, Hugel, B, Mallat, Z, Rossig, L, Tedgui, A, Zeiher, AM   +9 more
core   +1 more source

The Tip of the Four N-Terminal α-Helices of Clostridium sordellii Lethal Toxin Contains the Interaction Site with Membrane Phosphatidylserine Facilitating Small GTPases Glucosylation

Toxins, 2016
Clostridium sordellii lethal toxin (TcsL) is a powerful virulence factor responsible for severe toxic shock in man and animals. TcsL belongs to the large clostridial glucosylating toxin (LCGT) family which inactivates small GTPases by glucosylation with ...
Carolina Varela Chavez, Georges Michel Haustant, Bruno Baron, Patrick England, Alexandre Chenal, Serge Pauillac, Arnaud Blondel, Michel-Robert Popoff   +7 more
doaj   +1 more source

Hemagglutinating activity of phosphatidylserine [PDF]

FEBS Letters, 1983
In [l] we reported the structure and hemagglutinating activity of an ornithine-containing lipid of Bordetella pertussis. The proposed structure of the aminolipid is 3-hydroxyhexadecanoic acid amide-linked to ornithine and esterified to the second hexadecanoic acid. The aminolipid strongly agglutinated human and rabbit erythrocytes. Here, I describe the
openaire   +2 more sources

Tumor-Associated Exosomes: A Potential Therapeutic Target for Restoring Anti-Tumor T Cell Responses in Human Tumor Microenvironments

Cells, 2021
Exosomes are a subset of extracellular vesicles (EVs) that are released by cells and play a variety of physiological roles including regulation of the immune system. Exosomes are heterogeneous and present in vast numbers in tumor microenvironments.
Gautam N. Shenoy, Maulasri Bhatta, Richard B. Bankert   +2 more
doaj   +1 more source

Functional consequences of sphingomyelinase-induced changes in erythrocyte membrane structure. [PDF]

, 2012
Inflammation enhances the secretion of sphingomyelinases (SMases). SMases catalyze the hydrolysis of sphingomyelin into phosphocholine and ceramide.
Bosman, GJ, Brock, R, Cluitmans, JC, Dinkla, S, Fransen, J, Fuchs, B, Joosten, I, Schiller, J, Tomelleri, C, Verdurmen, WP, Wessels, K   +10 more
core   +1 more source

Developmental control of plant Rho GTPase nano-organization by the lipid phosphatidylserine

Science, 2019
GTPase clustering in response to a hormone Some lipid variants that are rare in plasma membranes function as signaling components. Studying root tip cells of the model plant Arabidopsis, Platre et al.
M. Platre, V. Bayle, Laia Armengot, J. Bareille, M. Marquès-Bueno, A. Creff, L. Maneta-Peyret, J. Fiche, M. Nollmann, C. Miège, P. Moreau, A. Martinière, Y. Jaillais   +12 more
semanticscholar   +1 more source

Ex Vivo Activation of Red Blood Cell Senescence by Plasma from Sickle-Cell Disease Patients: Correlation between Markers and Adhesion Consequences during Acute Disease Events

Biomolecules, 2021
BACKGROUND: Blood transfusion remains a key treatment for managing occlusive episodes and painful crises in sickle-cell disease (SCD). In that clinical context, red blood cells (RBCs) from donors and transfused to patients, may be affected by plasma ...
Philippe Chadebech, Gwellaouen Bodivit, Gaétana Di Liberto, Alicia Jouard, Corinne Vasseur, France Pirenne, Pablo Bartolucci   +6 more
doaj   +1 more source

In vivo stability of ester- and ether-linked phospholipid-containing liposomes as measured by perturbed angular correlation spectroscopy [PDF]

, 1988
To evaluate liposome formulations for use as intracellular sustained-release drug depots, we have compared the uptake and degradation in rat liver and spleen of liposomes of various compositions, containing as their bulk phospholipid an ether-linked ...
Baldeschwieler, John D., Derksen, Johannes T. P., Scherphof, Gerrit L.   +2 more
core   +1 more source

Molecular Electroporation and the Transduction of Oligoarginines

, 2009
Certain short polycations, such as TAT and polyarginine, rapidly pass through the plasma membranes of mammalian cells by an unknown mechanism called transduction as well as by endocytosis and macropinocytosis.
Alberts B, Alberts B, Alberts B, Alberts B, Alberts B, Bevers E, Bulte J W, Cahill K, Datta K, Grandmaison P A, Hanke M, Harbour J W, Hosotani R, Kevin Cahill, Kuge O, Mai J C, Mendoza N, Vaara M, Vance J E, Voelker D, Vondrášek J   +20 more
core   +1 more source

Sublytic Terminal Complement Components Induce Eryptosis in Autoimmune Haemolytic Anaemia Related to IgM Autoantibodies [PDF]

, 2019
BACKGROUND/AIMS: Eryptosis, the suicidal death of red blood cells (RBCs), is characterized by phosphatidylserine (PS) exposure at the cell surface. It can be catalysed by a variety of abnormal conditions and diseases.
Balola, Abdelwahab Hassan Ahmed, Bartolmäs, Thilo, Mayer, Beate, Salama, Abdulgabar   +3 more
core   +1 more source