Results 71 to 80 of about 108,878 (236)

Functional consequences of sphingomyelinase-induced changes in erythrocyte membrane structure. [PDF]

open access: yes, 2012
Inflammation enhances the secretion of sphingomyelinases (SMases). SMases catalyze the hydrolysis of sphingomyelin into phosphocholine and ceramide.
Bosman, GJ   +10 more
core   +1 more source

Measurement and models accounting for cell death capture hidden variation in compound response. [PDF]

open access: yes, 2020
Cancer cell sensitivity or resistance is almost universally quantified through a direct or surrogate measure of cell number. However, compound responses can occur through many distinct phenotypic outcomes, including changes in cell growth, apoptosis, and
Bae, Song Yi   +5 more
core   +1 more source

Towards the Development of Long Circulating Phosphatidylserine (PS)- and Phosphatidylglycerol (PG)-Enriched Anti-Inflammatory Liposomes: Is PEGylation Effective?

open access: yesPharmaceutics, 2021
The anionic phospholipids (PLs) phosphatidylserine (PS) and phosphatidylglycerol (PG) are endogenous phospholipids with anti-inflammatory and immunomodulatory activity.
Miriam E. Klein   +6 more
doaj   +1 more source

Antiphosphatidylserine antibody as a cause of multiple dural venous sinus thromboses and ST-elevation myocardial infarction [PDF]

open access: yes, 2018
Objective: Rare disease Background: Antiphospholipid syndrome (APS) is an autoimmune disease characterized by antibodies directed against phos-pholipids on plasma membranes. Through unclear mechanisms, APS confers hypercoagulability.
Marquardt, Caillin W.   +2 more
core   +1 more source

Enzymatic synthesis and decarboxylation of phosphatidylserine in Tetrahymena pyriformis

open access: yesJournal of Lipid Research, 1970
Cell-free extracts of the protozoan Tetrahymena pyriformis have been found to catalyze the following reactions: Phosphatidylethanolamine+L-Serine⇌Phosphatidylserine+EthanolaminePhosphatidylserine→Phosphatidylethanolamine+CO2Net:L-Serine→Ethanolamine ...
EDWARD A. DENNIS, EUGENE P. KENNEDY
doaj  

Novel engineered chimeric engulfment receptors trigger T cell effector functions against SIV-infected CD4+ T cells

open access: yesMolecular Therapy: Methods & Clinical Development, 2023
Adoptive therapy with genetically engineered T cells offers potential for infectious disease treatment in immunocompromised persons. HIV/simian immunodeficiency virus (SIV)-infected cells express phosphatidylserine (PS) early post infection.
Daniel Corey   +3 more
doaj  

Sublytic Terminal Complement Components Induce Eryptosis in Autoimmune Haemolytic Anaemia Related to IgM Autoantibodies [PDF]

open access: yes, 2019
BACKGROUND/AIMS: Eryptosis, the suicidal death of red blood cells (RBCs), is characterized by phosphatidylserine (PS) exposure at the cell surface. It can be catalysed by a variety of abnormal conditions and diseases.
Balola, Abdelwahab Hassan Ahmed   +3 more
core   +1 more source

Phosphatidylserine decarboxylase from Clostridium butyricum.

open access: yesJournal of Lipid Research, 1985
Phosphatidylserine decarboxylase activity has been characterized in membrane preparations from Clostridium butyricum ATCC 19398. A particulate fraction was shown to catalyze the formation of phosphatidylethanolamine and plasmenylethanolamine when ...
J N Verma, H Goldfine
doaj  

Exposure of phosphatidylserine on the cell surface [PDF]

open access: yesCell Death & Differentiation, 2016
Phosphatidylserine (PtdSer) is a phospholipid that is abundant in eukaryotic plasma membranes. An ATP-dependent enzyme called flippase normally keeps PtdSer inside the cell, but PtdSer is exposed by the action of scramblase on the cell's surface in biological processes such as apoptosis and platelet activation.
Jun Suzuki   +3 more
openaire   +3 more sources

Aggregation of Red Blood Cells: From Rouleaux to Clot Formation [PDF]

open access: yes, 2013
Red blood cells are known to form aggregates in the form of rouleaux. This aggregation process is believed to be reversible, but there is still no full understanding on the binding mechanism.
Steffen, P., Svetina, S., Wagner, C.
core   +2 more sources

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