Results 81 to 90 of about 108,878 (236)

On the mechanism of the mitochondrial decarboxylation of phosphatidylserine.

open access: yesJournal of Biological Chemistry, 1992
To study intramitochondrial phospholipid flow, radiolabeled phosphatidylserine was introduced into isolated rat liver mitochondria from donor vesicles through the action of a nonspecific lipid transfer protein. Imported phosphatidylserine was rapidly decarboxylated to phosphatidylethanolamine.
B Brigot   +4 more
openaire   +4 more sources

Does practice shape the brain? [PDF]

open access: yes, 1998
No abstract ...
Metcalfe, N.B.   +2 more
core   +1 more source

Specific stabilization of CFTR by phosphatidylserine

open access: yesBiochimica et Biophysica Acta (BBA) - Biomembranes, 2017
The Cystic Fibrosis Transmembrane Conductance Regulator (CFTR, ABCC7) is a plasma membrane chloride ion channel in the ABC transporter superfamily. CFTR is a key target for cystic fibrosis drug development, and its structural elucidation would advance those efforts.
Hanoch Senderowitz   +5 more
openaire   +3 more sources

Mechanisms of apoptotic phosphatidylserine exposure [PDF]

open access: yesCell Research, 2013
It has been a long-standing enigma which scramblase causes phosphatidylserine residues to be exposed on the surface of apoptotic cells, thereby facilitating the phagocytic recognition, engulfment and destruction of apoptotic corpses. In a recent paper in Science, Nagata and coworkers reveal that the scramblases Xkr8 and its C.
Guillermo Mariño, Guido Kroemer
openaire   +2 more sources

Investigating the evolution of apoptosis in malaria parasites: the importance of ecology [PDF]

open access: yes, 2010
Apoptosis is a precisely regulated process of cell death which occurs widely in multicellular organisms and is essential for normal development and immune defences.
Colegrave, Nick   +4 more
core   +2 more sources

Biotherapy of Brain Tumors with Phosphatidylserine-Targeted Radioiodinated SapC-DOPS Nanovesicles

open access: yesCells, 2020
Glioblastoma multiforme (GBM), a common type of brain cancer, has a very poor prognosis. In general, viable GBM cells exhibit elevated phosphatidylserine (PS) on their membrane surface compared to healthy cells.
Harold W. Davis   +10 more
doaj   +1 more source

Identification of Tim4 as a phosphatidylserine receptor [PDF]

open access: yesNature, 2007
In programmed cell death, a large number of cells undergo apoptosis, and are engulfed by macrophages to avoid the release of noxious materials from the dying cells. In definitive erythropoiesis, nuclei are expelled from erythroid precursor cells and are engulfed by macrophages.
Masanori Miyanishi   +6 more
openaire   +3 more sources

Anti-phospholipid-antibodies in patients with relapsing polychondritis [PDF]

open access: yes, 1998
Relapsing polychondritis (RP) is an extremly rare multisystemic disease thought to be of autoimmune origin. In order to assess if RP is associated with anti-phospholipid antibodies (aPL), clinical data and sera of 21 patients with RP were collected in a ...
B Lang   +11 more
core   +1 more source

Domain IV of Annexin A5 Is Critical for Binding Calcium and Guarantees Its Maximum Binding to the Phosphatidylserine Membrane

open access: yesMolecules, 2017
Background: Although domain IV of annexin A5 (anxA5) may be less effective in binding phosphatidylserine (PS), the four domains together may guarantee the maximum binding of anxA5 to the PS membrane. Additionally, previous research has shown that annexin
Jie Wang   +4 more
doaj   +1 more source

Recent advances in expanding the coverage of the lipidome [PDF]

open access: yes, 2017
The lipidome comprises a large array of molecules with diverse physicochemical properties. Lipids are structural components of cells, act as a source of energy, and function as signaling mediators.
Kamphorst, Jurre J., Tumanov, Sergey
core   +1 more source

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