Results 81 to 90 of about 133,958 (282)

Flipping the dogma – phosphatidylserine in non-apoptotic cell death

Cell Communication and Signaling, 2019
The exposure of phosphatidylserine (PS) on the outer plasma membrane has long been considered a unique feature of apoptotic cells. Together with other “eat me” signals, it enables the recognition and phagocytosis of dying cells (efferocytosis), helping ...
Inbar Shlomovitz, Mary Speir, M. Gerlic
semanticscholar   +1 more source

Caspase-independent programmed cell death triggers Ca2PO4 deposition in an in vitro model of nephrocalcinosis [PDF]

, 2018
We provide evidence of caspase-independent cell death triggering the calcification process in GDNF-silenced HK-2 ...
Anglani F., Ceol M, Cristofaro R, Del Prete D, Furlan C, Gianesello L, Priante G, Quaggio F, Terrin L   +8 more
core   +1 more source

Phosphatidylserine polarization is required for proper Cdc42 localization and for development of cell polarity. [PDF]

, 2010
We used genetically-encoded fluorescent probes to visualize the distribution of phosphatidylserine (PS) in live S. cerevisiae. The majority of the PS was found to reside in the cytosolic leaflet of the plasma membrane.
Gregory Fairn, Sergio Grinstein
core   +1 more source

Heterotrimeric G-protein subunit Gαi2 contributes to agonist-sensitive apoptosis and degranulation in murine platelets [PDF]

, 2018
Gαi2, a heterotrimeric G-protein subunit, regulates various cell functions including ion channel activity, cell differentiation, proliferation and apoptosis.
Birnbaumer, Lutz, Bissinger, Rosi, Cao, Hang, Gawaz, Meinrad, Lang, Elisabeth, Lang, Florian, Leiss, Veronika, Nürnberg, Bernd, Pelzl, Lisann, Pieske, Burkert, Qadri, Syed M., Umbach, Anja T., Voelkl, Jakob   +12 more
core   +1 more source

Phosphatidylserine transport in Rhnull erythrocytes [PDF]

Blood, 1990
Abstract Phosphatidylserine transport in normal and Rhnull red blood cells was determined by measuring characteristic morphologic changes induced by synthetic phospholipids. Treating normal A+ cells with commercial anti- A antisera, anti-Rho(D) antisera, or with saturating concentrations of purified Rho(D) antibodies had no effect on ...
R E, Smith, D L, Daleke
openaire   +3 more sources

Importance of Efferocytosis in COVID-19 Mortality

Infection and Drug Resistance, 2022
Adnan Erol Independent Researcher, Not Affiliated to Any Institution, Silivri-Istanbul, TurkeyCorrespondence: Adnan Erol, Independent Researcher, Not Affiliated to Any Institution, Silivri-Istanbul, Turkey, Email eroladnan@protonmail.comAbstract: COVID ...
Erol A
doaj  

Physiological consequences of disruption of mammalian phospholipid biosynthetic genes

Journal of Lipid Research, 2009
By 1959, Eugene Kennedy and coworkers had outlined most pathways of phospholipid biosynthesis. In the next four decades, the emphasis was on enzymology and regulation of these pathways.
Dennis E. Vance, Jean E. Vance
doaj   +1 more source

Nanoscopic Spatial Association between Ras and Phosphatidylserine on the Cell Membrane Studied with Multicolor Super Resolution Microscopy

Biomolecules, 2022
Recent work suggests that Ras small GTPases interact with the anionic lipid phosphatidylserine (PS) in an isoform-specific manner, with direct implications for their biological functions.
Anna M. Koester, Kai Tao, Malwina Szczepaniak, Matthew J. Rames, Xiaolin Nan   +4 more
doaj   +1 more source

Does practice shape the brain? [PDF]

, 1998
No abstract ...
Metcalfe, N.B., Monaghan, P., Ruxton, G.D.   +2 more
core   +1 more source

Fluoxetine Induced Suicidal Erythrocyte Death

Toxins, 2013
The antidepressant fluoxetine inhibits ceramide producing acid sphingomyelinase. Ceramide is in turn known to trigger eryptosis the suicidal death of erythrocytes characterized by cell shrinkage and exposure of phosphatidylserine at the erythrocyte ...
Florian Lang, Majed Abed, Ahmad Almilaji, Rosi Bissinger, Sigrid Enkel, Kashif Jilani   +5 more
doaj   +1 more source