Results 81 to 90 of about 108,878 (236)
On the mechanism of the mitochondrial decarboxylation of phosphatidylserine.
To study intramitochondrial phospholipid flow, radiolabeled phosphatidylserine was introduced into isolated rat liver mitochondria from donor vesicles through the action of a nonspecific lipid transfer protein. Imported phosphatidylserine was rapidly decarboxylated to phosphatidylethanolamine.
B Brigot+4 more
openaire +4 more sources
Does practice shape the brain? [PDF]
No abstract ...
Metcalfe, N.B.+2 more
core +1 more source
Specific stabilization of CFTR by phosphatidylserine
The Cystic Fibrosis Transmembrane Conductance Regulator (CFTR, ABCC7) is a plasma membrane chloride ion channel in the ABC transporter superfamily. CFTR is a key target for cystic fibrosis drug development, and its structural elucidation would advance those efforts.
Hanoch Senderowitz+5 more
openaire +3 more sources
Mechanisms of apoptotic phosphatidylserine exposure [PDF]
It has been a long-standing enigma which scramblase causes phosphatidylserine residues to be exposed on the surface of apoptotic cells, thereby facilitating the phagocytic recognition, engulfment and destruction of apoptotic corpses. In a recent paper in Science, Nagata and coworkers reveal that the scramblases Xkr8 and its C.
Guillermo Mariño, Guido Kroemer
openaire +2 more sources
Investigating the evolution of apoptosis in malaria parasites: the importance of ecology [PDF]
Apoptosis is a precisely regulated process of cell death which occurs widely in multicellular organisms and is essential for normal development and immune defences.
Colegrave, Nick+4 more
core +2 more sources
Biotherapy of Brain Tumors with Phosphatidylserine-Targeted Radioiodinated SapC-DOPS Nanovesicles
Glioblastoma multiforme (GBM), a common type of brain cancer, has a very poor prognosis. In general, viable GBM cells exhibit elevated phosphatidylserine (PS) on their membrane surface compared to healthy cells.
Harold W. Davis+10 more
doaj +1 more source
Identification of Tim4 as a phosphatidylserine receptor [PDF]
In programmed cell death, a large number of cells undergo apoptosis, and are engulfed by macrophages to avoid the release of noxious materials from the dying cells. In definitive erythropoiesis, nuclei are expelled from erythroid precursor cells and are engulfed by macrophages.
Masanori Miyanishi+6 more
openaire +3 more sources
Anti-phospholipid-antibodies in patients with relapsing polychondritis [PDF]
Relapsing polychondritis (RP) is an extremly rare multisystemic disease thought to be of autoimmune origin. In order to assess if RP is associated with anti-phospholipid antibodies (aPL), clinical data and sera of 21 patients with RP were collected in a ...
B Lang+11 more
core +1 more source
Background: Although domain IV of annexin A5 (anxA5) may be less effective in binding phosphatidylserine (PS), the four domains together may guarantee the maximum binding of anxA5 to the PS membrane. Additionally, previous research has shown that annexin
Jie Wang+4 more
doaj +1 more source
Recent advances in expanding the coverage of the lipidome [PDF]
The lipidome comprises a large array of molecules with diverse physicochemical properties. Lipids are structural components of cells, act as a source of energy, and function as signaling mediators.
Kamphorst, Jurre J., Tumanov, Sergey
core +1 more source