Results 121 to 130 of about 157,779 (296)

Metformin Impairs Breast Cancer Growth through the Inhibition of PRMT6

Advanced Science, EarlyView.
Metformin has a biological activity against breast cancer. However, it is largely unknown about its precise therapeutic targets. Here, histone arginine methyltransferase PRMT6 is identified as a new anti‐cancer target for metformin. Metformin directly binds PRMT6 and inhibits its ability to catalyze histone H3R2 asymmetric dimethylation (H3R2me2a ...
Yinsheng Wu, Xinlin Xu, Yue Tong, Min Wang, Feng Ge, Min Wu, Yunlong Wang, Gang Chen, Xilan Yu, Shanshan Li   +9 more
wiley   +1 more source

The Extraction of Curium and Americium by Tri-n-Octyl Phosphine Oxide [PDF]

, 1964
Kenju WATANABE, Reiko Ono
openalex   +1 more source

NAD⁺ Reduction in Glutamatergic Neurons Induces Lipid Catabolism and Neuroinflammation in the Brain via SARM1

Advanced Science, EarlyView.
NAD⁺ homeostasis maintains neuronal integrity through opposing actions of NMNAT2 and SARM1. Loss of NMNAT2 in glutamatergic neurons reprograms cortical metabolism from glucose to lipid catabolism, depletes lipid stores, and triggers inflammation and neurodegeneration.
Zhen‐Xian Niou, Sen Yang, Andrea Enriquez, Nino A. Espinas, Anoosha Sri, Caliel D. Hines, Jason M. Tennessen, Chia‐Shan Wu, Jui‐Yen Huang, Hui‐Chen Lu   +9 more
wiley   +1 more source

Chemical and Electrochemical Oxidation of Tris(3,5‐di‐tert‐butylphenyl)phosphine – High Z′ Crystal Structures and Conformational Effects Associated with Bulky meta Substituents [PDF]

, 2018
Ivelise Dimbarre Lao Guimarães, Jarem Raul Garcia, Karen Wohnrath, Renè T. Boeré   +3 more
openalex   +1 more source

Development of Endogenous Protein Probes for Characterizing Surface Proteins and Cellular Interactors of Extracellular Vesicles

Advanced Science, EarlyView.
The proximity labeling enzyme APEX2 is displayed on extracellular vesicle (EV) surfaces via genetic fusion with EV‐sorting scaffolds, enabling in situ biotinylation of native surface proteins, adsorbed corona components, and interacting cellular proteins.
Wenyi Zheng, Metoboroghene Mowoe, Wenqing Hou, Daniel W. Hagey, Koshi Imami, Samir EL Andaloussi   +5 more
wiley   +1 more source

Modeling the Efficacy of Phosphine on Eggs of Major Stored-Product Insect Species: Investigating Strains with Varying Susceptibility Levels

Agriculture
Phosphine is a widely utilized fumigant insecticide in stored-product facilities; however, its excessive application and improper usage have contributed to the emergence of resistance in insect populations.
Marina Gourgouta, Maria K. Sakka, Evmorfia P. Bataka, M. Carolin Götze, Christos T. Nakas, Christos G. Athanassiou   +5 more
doaj   +1 more source

First-Principle Study of Phosphine Adsorption on Si(001)-2 × 1–Cl [PDF]

, 2017
Т. В. Павлова, G. M. Zhidomirov, K. N. Eltsov   +2 more
openalex   +1 more source

Ultrathin, Unsinkable, Janus‐Faced Solar–Thermal Interfacial Evaporator for High‐Throughput Seawater Distillation and Solar‐Water Production

Advanced Science, EarlyView.
A nanostructured carbon‐coated porous polymeric scaffold is developed to accelerate the hydrological cycle, enabling solar–thermal freshwater production from saline water with reduced energy consumption and CO2 footprint. Abstract Solar–thermal distillation offers immense and hitherto untapped potential for energy‐efficient, sustainable freshwater ...
Mohammed Aslam Villan, Amrutha Suresh, Mukund Misra, Cintia Naranjo Ruiz, Neil R. Cameron, Sandip K. Saha, Subramaniam Chandramouli   +6 more
wiley   +1 more source

Resistance of Stored Grain Pests to Phosphine and Its Integrated Management Strateg

Liang you shipin ke-ji
The fumigant has been approved by the World Health Organization for use in grain storage, targeting the eradication of pests in areas where grain is stored or transported to reduce insect and mold activities, thereby minimizing storage losses.
ZHANG Hui-yan, CHEN Xin, ZHANG Hong-qing, LI Yan-yu, TIAN Xiao-wei, ZHOU Gui-ming, TAO Hai-hua, GONG Jian-min   +7 more
doaj   +1 more source

Isomer Dependence in the Assembly and Lability of Silver(I) Trifluoromethanesulfonate Complexes of the Heteroditopic Ligands, 2-, 3-, and 4-[Di(1\u3cem\u3eH\u3c/em\u3e-pyrazolyl)methyl]phenyl(di-\u3cem\u3ep\u3c/em\u3e-tolyl)phosphine [PDF]

, 2014
Three isomers of a new heteroditopic ligand that contains a di(1H-pyrazolyl)methyl (−CHpz2) moiety connected to a di(p-tolyl)phosphine group via a para-, meta-, or ortho-phenylene spacer (pL, mL, and oL, respectively) have been synthesized by using a ...
Gardinier, James R., Hewage, Jeewantha S., Lindeman, Sergey V.   +2 more
core   +1 more source