Results 171 to 180 of about 48,855 (331)

Lactate and hydrogen ions play a predominant role in evoking the exercise pressor reflex during ischaemic contractions but not during freely perfused contractions

The Journal of Physiology, EarlyView.
Abstract figure legend The role of lactate and hydrogen ions in evoking the metabolic component of the exercise pressor reflex was studied in rats with either a functional pygm gene (pygm+/+) or with a non‐functional “knocked out” pygm gene (pygm−/−). The pygm gene is responsible for producing the myophosphorylase enzyme which catalyses the breakdown ...
Guillaume P. Ducrocq, Laura Anselmi, Victor Ruiz‐Velasco, Marc P. Kaufman   +3 more
wiley   +1 more source

GluN2C/D‐containing NMDA receptors enhance temporal summation and increase sound‐evoked and spontaneous firing in the inferior colliculus

The Journal of Physiology, EarlyView.
Abstract figure legend Here, we find that GluN2D‐containing NMDA receptors (NMDARs) are expressed by most vasoactive intestinal peptide neurons in the inferior colliculus (IC). These receptors are less susceptible to Mg2+ blockade compared to GluN2A/B‐containing NMDARs, allowing ions to flow at resting membrane potential.
Audrey C. Drotos, Rachel L. Zarb, Victoria Booth, Michael T. Roberts   +3 more
wiley   +1 more source

The effect of phosphocreatine on the distribution of different subunits of translation elongation factor 1 in gently permeabilized human fibroblasts [PDF]

, 1997
B. S. Negrutskii
openalex   +1 more source

Volitional exercise elicits physiological and molecular improvements in the severe D2.mdx mouse model of Duchenne muscular dystrophy

The Journal of Physiology, EarlyView.
Abstract figure legend This study investigated the effects of volitional exercise on muscle health in the more severe D2.mdx model of Duchenne muscular dystrophy (DMD). We showed that 8–10 weeks of a relatively high volume of voluntary wheel running (VWR) in D2.mdx animals augmented select muscle mass and normalized ex vivo muscle force compared to ...
Stephanie R. Mattina, Sean Y. Ng, Andrew I. Mikhail, Derek W. Stouth, Cora E. Jornacion, Irena A. Rebalka, Thomas J. Hawke, Vladimir Ljubicic   +7 more
wiley   +1 more source

Linear Relation between Cerebral Phosphocreatine Concentration and Memory Capacities during Permanent Brain Vessel Occlusions in Rats [PDF]

, 2000
Konstanze Plaschke, Seong‐Wook Yun, Eike Martin, Siegfried Hoyer, Hubert J. Bardenheuer   +4 more
openalex   +1 more source

Intracellular compartmentation, structure and function of creatine kinase isoenzymes in tissues with high and fluctuating energy demands: the 'phosphocreatine circuit' for cellular energy homeostasis.

Biochemical Journal, 1992
T. Wallimann, M. Wyss, D. Brdiczka, Klaas Nicolay, H. Eppenberger   +4 more
semanticscholar   +1 more source

Control of action potential afterdepolarizations in the inferior olive by inactivating A‐type currents through KV4 channels

The Journal of Physiology, EarlyView.
Abstract figure legend KV4 channel availability regulates inferior olive action potential duration. The durations of action potentials in inferior olive neurons (blue) depend strongly on preceding membrane potential, with afterdepolarizations varying over the physiological range by almost two orders of magnitude (open circles). Voltage clamp recordings
Ziyad W. Sultan, Marion Najac, Indira M. Raman   +2 more
wiley   +1 more source

Optimal Pacing for Running 400 m and 800 m Track Races

, 2012
Physicists seeking to understand complex biological systems often find it rewarding to create simple "toy models" that reproduce system behavior. Here a toy model is used to understand a puzzling phenomenon from the sport of track and field.
Baumann W., Gajer B., Hanon C., Hirvonen J., Hultman E., James Reardon, Matrahazi Imre, Sage A., Sahlin K., Čoh M.   +9 more
core   +1 more source

Comparative Analysis of Energy System Demands and Performance Metrics in Professional Soccer Players: Running vs. Cycling Repeated Sprint Tests

Applied Sciences
Background: Repeated sprint ability (RSA) is defined as the ability to recover and maintain maximal effort during repeated sprints, recognised as a crucial performance component in team sports. The exercise mode used to test RSA may influence performance
Erkan Tortu, Gökhan Deliceoglu
doaj   +1 more source

Mitochondrial efficiency in resting skeletal muscle in vivo: a novel non‐invasive approach using multinuclear magnetic resonance spectroscopy in humans

The Journal of Physiology, Volume 603, Issue 6, Page 1503-1519, 15 March 2025.
Abstract figure legend This graphical abstract illustrates our novel, non‐invasive approach using combined 31P/1H magnetic resonance spectroscopy (MRS) to measure mitochondrial efficiency in resting human skeletal muscle in vivo. In this study, we quantified mitochondrial efficiency from the ATP synthesis rate and myoglobin‐derived VO2 in the plantar ...
Muhammet Enes Erol, Sean T. Bannon, Alexs A. Matias, Triantafyllia Siokas, Rajakumar Nagarajan, Yann Le Fur, Song‐Young Park, Gwenael Layec   +7 more
wiley   +1 more source