Results 191 to 200 of about 52,049 (355)
Metabolic and Neuroenergetic Effects of Intranasal Vitamin C Application in the Human Brain. [PDF]
Ingwersen LC +3 more
europepmc +1 more source
3D‐mapping of phosphocreatine concentration in the human calf muscle at 7 T: Comparison to 3 T
P. Parasoglou +3 more
semanticscholar +1 more source
Temporal Transcriptional Regulation of Human Neuronal Differentiation via Forward Programming
Single‐cell profiling of TF‐induced forward programming versus stepwise dual‐SMAD differentiation reveals that divergent trajectories set the pace of neurogenesis. OLIG TFs advance cell‐cycle exit via NOTCH modulation, while NEUROD2 later accelerates maturation. The study elucidates transcriptional mechanisms governing differentiation timing, providing
Lingling Zhu +13 more
wiley +1 more source
Additive Anticancer and Antioxidant Effects of Metformin and Luteolin in Breast and Colorectal Cancer Cell Lines. [PDF]
Gębczak K +3 more
europepmc +1 more source
Spectrally selective 3D TSE imaging of phosphocreatine in the human calf muscle at 3 T
P. Parasoglou, D. Xia, R. Regatte
semanticscholar +1 more source
HUWE1 in Skeletal Muscle Prevents Muscle Fatigue via Maintaining Iron and Calcium Homeostasis
This study investigates the impact of iron homeostasis on exercise. Loss of the HECT domain‐containing ubiquitin ligase E3 (HUWE1) in skeletal muscle restrains the exercise performance in mice with downregulated ferroportin expression leading to iron overload, which is ameliorated by dietary iron restriction.
Huike Jiao +10 more
wiley +1 more source
On the mechanisms of neuroprotection by creatine and phosphocreatine [PDF]
Nickolay Brustovetsky +2 more
openalex +1 more source
Glutathione (GSH) defines oxidative balance, but can it directly tune central metabolism? The research reveals that GSH binds and potently activates pyruvate kniase M2 (PKM2), rewiring glycolysis and dictating ferroptosis sensitivity. Combining GSH depletion with PKM2 activation triggers mitochondrial damage and lipid peroxidation, profoundly ...
Tsan‐Jan Chen +17 more
wiley +1 more source

