Red blood cell endothelial nitric oxide synthase: A major player in regulating cardiovascular health
British Journal of Pharmacology, EarlyView., 2023 Abstract Red blood cells (RBCs) have traditionally been seen as simple carriers of gases and nutrients in the body. One important non‐canonical function of RBCs in the cardiovascular system is the regulation of nitric oxide (NO) metabolism. It has been shown that RBCs can scavenge NO, transport NO metabolites and produce NO in hypoxic conditions ...
Anthea LoBue +7 more
wiley +1 more source
Chemical exchange saturation transfer imaging of phosphocreatine in the muscle
Magnetic Resonance in Medicine, 2019 To determine the exchange parameters for the CEST of phosphocreatine (PCrCEST) in phantoms and to characterize PCrCEST in vivo in the muscle at different saturation powers and magnetic fields.
J. Chung +3 more
semanticscholar +1 more source
Neuroprotective effects of some creatine derivative compounds
Journal of Biological Research, 2010 Some derivatives more lipophylic than creatine, thus theoretically being capable to better cross the blood-brain barrier, were studied for their neuroprotective effect in mouse hippocampal slices.
L. Perasso +3 more
doaj +1 more source
Creatine kinase in energy metabolic signaling in muscle [PDF]
, 2007 There has been much debate on the mechanism of regulation of mitochondrial ATP synthesis to balance ATP consumption during changing cardiac workloads. A key role of creatine kinase (CK) isoenzymes in this regulation of oxidative phosphorylation and in ...
Johannes H. G. M. van Beek, Olav Kongas
core +2 more sources
Enzymatic Estimation of Phosphocreatine.
Experimental Biology and Medicine, 1962 SummaryAn enzymatic micro-method has been described which permits simultaneous determination of adenosine triphosphate and phosphocreatine in extracts corresponding to 2-5 mg of muscle. The method has been found to be essentially in agreement with the colorimetric method of Fiske and Subbarow. Phosphocreatine in tissues containing more than 2% glycogen
G. Fawaz +2 more
openaire +3 more sources
Dual mechanism of brain injury and novel treatment strategy in maple syrup urine disease [PDF]
, 2009 Maple syrup urine disease (MSUD) is an inherited disorder of branched-chain amino acid metabolism presenting with lifethreatening cerebral oedema and dysmyelination in affected individuals.
Ara jo +44 more
core +2 more sources
Rapid, $B_1$-insensitive, dual-band quasi-adiabatic saturation transfer with optimal control for complete quantification of myocardial ATP flux [PDF]
, 2020 Purpose: Phosphorus saturation-transfer experiments can quantify metabolic fluxes non-invasively. Typically, the forward flux through the creatine-kinase reaction is investigated by observing the decrease in phosphocreatine (PCr) after saturation of $\gamma$-ATP.
arxiv +1 more source
Magnetic resonance spectroscopy in migraine: what have we learned so far? [PDF]
, 2012 Objective: To summarize and evaluate proton (H-1) and phosphorus (P-31) magnetic resonance spectroscopy (MRS) findings in migraine. Methods: A thorough review of H-1 and/or P-31-MRS studies in any form of migraine published up to September 2011 ...
Achten, Eric +2 more
core +2 more sources
Increased Adenine Nucleotide Degradation in Skeletal Muscle Atrophy [PDF]
, 2019 Adenine nucleotides (AdNs: ATP, ADP, AMP) are essential biological compounds that facilitate many necessary cellular processes by providing chemical energy, mediating intracellular signaling, and regulating protein metabolism and solubilization.
Brault, Jeffrey J. +2 more
core +1 more source
³¹P Saturation Transfer and Phosphocreatine Imaging in the Monkey Brain [PDF]
, 1991 ³¹P magnetic resonance imaging with chemical-shift discrimination by selective excitation has been employed to determine the phosphocreatine (PCr) distribution in the brains of three juvenile macaque monkeys.
Allman, John +4 more
core +1 more source