Results 191 to 200 of about 225,115 (385)

Phosphodiesterase 2 Protects Against Catecholamine-Induced Arrhythmia and Preserves Contractile Function After Myocardial Infarction

Circulation Research, 2017
C. Vettel, Marta Lindner, M. Dewenter, K. Lorenz, Constanze Schanbacher, Merle Riedel, Simon Lämmle, S. Meinecke, F. Mason, S. Sossalla, A. Geerts, Michael Hoffmann, F. Wunder, F. Brunner, T. Wieland, Hind Mehel, S. Karam, P. Lechène, J. Leroy, G. Vandecasteele, Michael Wagner, R. Fischmeister, A. El-Armouche   +22 more
semanticscholar   +1 more source

Variations in alcohol craving and negative mood during a clinical trial of ibudilast for alcohol use disorder

Alcohol, Clinical and Experimental Research, EarlyView.
Neuroimmune compounds are being investigated as novel treatments for alcohol use disorder (AUD). This secondary analysis of a randomized clinical trial of ibudilast for AUD (N = 102) evaluated changes in self‐report symptom measures of craving, depression, and anxiety collected monthly over 12 weeks.
Lindsay R. Meredith, Erica N. Grodin, Craig K. Enders, Lara A. Ray   +3 more
wiley   +1 more source

A New Cyclic Phosphodiesterase Having a 3'-Nucleotidase Activity from Escherichia coli B

, 1964
Yasuhiro Anraku
openalex   +1 more source

Diagnosis and Management of Hypersensitivity to Antiplatelet Drugs: EAACI Position Paper

Allergy, EarlyView.
ABSTRACT Antiplatelet drug (APD) therapy is the cornerstone for the prevention of atherosclerotic cardiovascular disease. The main APDs are aspirin and thienopyridines, particularly clopidogrel. These drugs may induce hypersensitivity reactions (HSRs).
Gabriele Cortellini, Alla Nakonechna, Annick Barbaud, Sevim Bavbek, Gianfranco Calogiuri, Inmaculada Doña, Violeta Kvedariene, Jose Julio Laguna Martinez, Serena Liberati, Mauro Pagani, Antonino Romano   +10 more
wiley   +1 more source

Characterization of cyclic nucleotide phosphodiesterase isoenzymes in the human ureter and their functional role in vitro [PDF]

, 1994
Forssmann, W. G., Jonas, Udo, Meyer, M. F., Schulz-Knappe, P., Stief, Christian Georg, Taher, A., Truss, Michael C.   +6 more
core   +1 more source

Partial Purification and Properties of Phosphodiesterase I from Hog Kidney

, 1961
W.E. Razzell
openalex   +1 more source

Competitive Inhibition of Beef Heart Cyclic AMP Phosphodiesterase by Cytokinins and Related Compounds [PDF]

, 1974
Sidney M. Hecht, Robert Faulkner, S. D. Hawrelak   +2 more
openalex   +1 more source

Myeloid cAMP Reduction Shifts Rhinovirus‐Induced Airway Inflammation From Neutrophilic to Eosinophilic by Suppressing M1‐Interstitial Macrophages

Allergy, EarlyView.
ABSTRACT Background Asthma exacerbations caused by human rhinovirus (hRV) infection are characterized by airway neutrophilia and reduced corticosteroid response, leading to significant healthcare costs and lung function impairment. The Gαs subunit of the trimeric G protein regulates immunopathological conditions by modulating cAMP levels.
Seong Ok Park, Erdenebileg Uyangaa, Hyo Jin Kim, Hee Won Byeon, Jin Young Choi, Koanhoi Kim, Jihyung Lee, Samuel Bertin, Eyal Raz, Seong Kug Eo   +9 more
wiley   +1 more source

Activity of 3′, 5′-AMP phosphodiesterase in liver and adipose tissue of normal and diabetic rats

, 1968
B. Müller‐Oerlinghausen, U. Schwabe, A. Hasselblatt, F. H. Schmidt   +3 more
openalex   +1 more source

An HD-domain phosphodiesterase mediates cooperative hydrolysis of c-di-AMP to affect bacterial growth and virulence

Proceedings of the National Academy of Sciences of the United States of America, 2015
TuAnh N. Huynh, Shukun Luo, D. Pensinger, J. Sauer, L. Tong, J. Woodward   +5 more
semanticscholar   +1 more source