New Prospective Phosphodiesterase Inhibitors: Phosphorylated Oxazole Derivatives in Treatment of Hypertension. [PDF]
Adv Pharm Bull, 2023 Nizhenkovska IV +5 more
europepmc +1 more source
A heat‐stable inhibitor protein for bovine brain cyclic nucleotide phosphodiesterase from Escherichia coli [PDF]
, 1981 Yasushi Iwasa +4 more
openalex +1 more source
Genital Psoriasis: Shining Light on This Hidden Disease
JEADV Clinical Practice, EarlyView.Psoriasis occurring on skin of the genital and perigenital regions has specific diagnostic and treatment requirements due to the sensitivity and private nature of these areas. A multidisciplinary group of experts in the management of genital psoriasis, the Genital Psoriasis Wellness Consortium, convened to discuss the impact of genital psoriasis on ...
Jennifer Cather +19 more
wiley +1 more source
A model for the regulation of the calmodulin-dependent enzymes erythrocyte Ca2+-transport ATPase and brain phosphodiesterase by activators and inhibitors [PDF]
, 1982 K Gietzen, I Sadorf, Hermann Bader
openalex +1 more source
Efficacy of Apremilast in Refractory Genital Psoriasis: A Retrospective Case Series
JEADV Clinical Practice, EarlyView.ABSTRACT Background Genital pustular psoriasis is a rare and often underdiagnosed condition that can severely affect physical comfort, quality of life and psychological well‐being. It can be particularly challenging to manage, often requiring systemic therapies due to its potential unresponsiveness to conventional topical treatment.
Jonathan Krygier +2 more
wiley +1 more source
Purin-6-One Derivatives as Phosphodiesterase-2 Inhibitors
Journal of Chemistry, 2016 A series of purin-6-one derivatives were synthesized, and their in vitro inhibitory activity against phosphodiesterase-2 (PDE2) was evaluated by using a fluorescence polarization assay.
Wei Yuan +3 more
doaj +1 more source
Pharmacokinetic/Pharmacodynamic Assessment of Selective Phosphodiesterase Inhibitors in a Mouse Model of Autoimmune Hepatitis. [PDF]
J Pharmacol Exp Ther, 2022 Świerczek A +3 more
europepmc +1 more source
Induction of dark-adaptive retinomotor movement (cell elongation) in teleost retinal cones by cyclic adenosine 3,5-monophosphate. [PDF]
, 1982 In the teleost retina, the photoreceptors and retinal pigment epithelium (RPE) undergo extensive movements (called retinomotor movements) in response to changes in light conditions and to an endogenous circadian rhythm.
BURNSIDE, Beth +3 more
core
The action of islet activating protein (pertussis toxin) on insulin's ability to inhibit adenylate cyclase and activate cyclic AMP phosphodiesterases in hepatocytes [PDF]
, 1986 C M Heyworth +4 more
openalex +1 more source
Journal of Pharmacological Sciences, 2013 Phosphodiesterase 4 (PDE4) inhibitors have been developed for the treatment of pulmonary inflammatory diseases, but their clinical use was dose-limited by mainly gastric adverse effects.
Osamu Suzuki +12 more
doaj