Results 241 to 250 of about 86,123 (283)

Tissue‐Specific Extracellular Vesicles Enriched From Circulation: Exploring the Liquid Biopsy Perspective

Journal of Extracellular Biology, Volume 5, Issue 2, February 2026.
ABSTRACT Extracellular vesicles (EVs) released from tissues can be found in human biofluids. EVs reflect the phenotypic state of their cell of origin, carrying informative molecular biomarkers within and between tissues, and represent a promising target for liquid biopsy.
Biancamaria Pierri, Erez Eitan, Kenneth W. Witwer, Diane B. Re, Andrea A. Baccarelli, Haotian Wu   +5 more
wiley   +1 more source

Oligodendrocyte: Development, Plasticity, Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
The oligodendrocyte lineage and its roles in development, plasticity, and CNS homeostasis have been shown to have the potential to treat neurological diseases. However, the main obstacles to clinical translation, particularly in terms of BBB challenges and precise delivery.
Qiong Xiang, Ruo‐Lan Shi, You‐Xia Huang, Li‐Ni Liu, Jia‐Sheng Tao, Xian‐Hui Li, Xiao‐Da Li   +6 more
wiley   +1 more source

Unlocking the genetic control of early seedling resistance to wheat powdery mildew through microphenomics

Pest Management Science, Volume 82, Issue 2, Page 1668-1679, February 2026.
Microphenomics is a new technique for detecting the very early resistance of powdery mildew in wheat seedlings, after 24, 48, and 72 h from infection. A number of 29, 42, and 34 genes models were identified to harbor significant SNP markers associated with the early resistance to WPM.
Amira M.I. Mourad, Hanaa M.S. Ibrahim, Stefanie Lück, Andreas Börner, Dimitar Douchkov   +4 more
wiley   +1 more source

Green synthesis of silver nanoparticles using fermentation extracts from a mangrove soil bacterium: morphological characterization, and antifungal activities against rice blast fungus

Pest Management Science, Volume 82, Issue 2, Page 2035-2047, February 2026.
This study synthesized silver nanoparticles (RFE‐AgNPs) with multifaceted inhibitory effects on Pyricularia oryzae using mangrove soil bacterial natural products and evaluated their toxicity effects on Artemia salina. Abstract BACKGROUND Rice blast, caused by Pyricularia oryzae, poses a formidable threat to global rice production.
Liwang Fei, Jianbing Liang, Shiquan Fu, Ying Xu, Lingyun Hao   +4 more
wiley   +1 more source

Associations between phosphodiesterase type 5 inhibitors and vascular function: a systematic review and meta-analysis on randomized-controlled trials. [PDF]

Syst Rev
Zhang Y, Peng H, Xin S, Mao J, Zhang J, Li H, Luan Y, Liu X, Wang T, Liu J, Zhang H, Song W.   +11 more
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Phosphodiesterase inhibitors

Current Anaesthesia & Critical Care, 1993
Despite the justifiable concern about the use of oral cyclic adenosine monophosphate phosphodiesterase (cAMP PDE) inhibitors, the intravenous preparations are clearly effective in the treatment of acute heart failure, whether it occurs de novo or complicating chronic congestive heart failure (CHF), and in low output states following cardiac surgery ...
R, Andrews, A J, Cowley
  +6 more sources

Phosphodiesterase 4 inhibitors

Journal of the American Academy of Dermatology, 2018
Historically, drugs available for treating atopic dermatitis (AD) have been limited to topical corticosteroids and topical calcineurin inhibitors, with systemic immunosuppressants and phototherapy reserved for severe AD. Despite their efficacy and infrequent adverse events, phobia about the use of topical steroids and calcineurin inhibitors has limited
Rema, Zebda, Amy S, Paller
openaire   +2 more sources

Phosphodiesterase-5 Inhibitors

2013
Nitric oxide (NO) signaling plays a key role in modulating vascular tone and remodeling in the pulmonary circulation. The guanylate cyclase/cyclic guanylate monophosphate-signaling pathway primarily mediates nitric oxide signaling. This pathway is critical in normal regulation of the pulmonary vasculature, and is an important target for therapy in ...
Barbara A, Cockrill, Aaron B, Waxman
openaire   +2 more sources