Results 241 to 250 of about 87,967 (330)

Rolipram, a Selective Inhibitor of Phosphodiesterase Type 4, Pronouncedly Enhanced the Forskolin-Induced Promotion of Dopamine Biosynthesis in Primary Cultured Rat Mesencephalic Neurons.

, 1997
Nobuyuki Yamashita, Mio Miyashiro, Jun Baba, Aiko Sawa   +3 more
openalex   +2 more sources

Phosphodiesterase Inhibitors Revert Axonal Dystrophy in Friedreich's Ataxia Mouse Model. [PDF]

Neurotherapeutics, 2019
Mollá B, Muñoz-Lasso DC, Calap P, Fernandez-Vilata A, de la Iglesia-Vaya M, Pallardó FV, Moltó MD, Palau F, Gonzalez-Cabo P.   +8 more
europepmc   +1 more source

Comorbid Diabetes Mellitus Contributes to Residual Overactive Bladder After Transurethral Surgery for Benign Prostatic Hyperplasia

International Journal of Urology, EarlyView.
ABSTRACT Objectives This study aimed to investigate the factors associated with residual overactive bladder after transurethral surgery for benign prostatic hyperplasia. Methods This study retrospectively analyzed male patients aged 50 years or older who underwent transurethral surgery for benign prostatic hyperplasia with overactive bladder between ...
Koji Miki, Keisuke Kiba, Daisuke Maenosono, Yasunori Akashi, Mamoru Hashimoto, Yutaka Yamamoto, Kazutoshi Fujita, Akihide Hirayama   +7 more
wiley   +1 more source

E4021, A Novel cGMP Phosphodiesterase (PDE5) Inhibitor, Improves Pulmonary Hemodynamics in Newborn Lambs with PPHN † 1645 [PDF]

, 1998
Robert C Dukarm, James A. Russell, Sylvia F. Gugino, Frederick C. Morin, Robin H. Steinhorn   +4 more
openalex   +1 more source

Erectile dysfunction in dermatology and venereology: From aetiopathogenic mechanisms to practical considerations for dermato‐venereologists

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Multiple inflammatory, infectious and autoimmune dermato‐venereological conditions are associated with erectile dysfunction (ED) due to underlying intricate vasculogenic, neurogenic, endocrine and psychogenic mechanisms. It is recommended that practitioners screen dermatology patients for ED and associated comorbidities, provide personalized lifestyle ...
Andrei Tanasov, George‐Sorin Tiplica
wiley   +1 more source

Activation and suppression mechanisms of the NRG1 helper NLRs

Journal of Integrative Plant Biology, EarlyView.
This commentary examines two recent papers featuring intriguing discoveries on the molecular processes and structural foundations involved in the activation and suppression of the N‐requirement gene 1 (NRG1) helper nucleotide‐binding leucine‐rich repeat receptor.
Yu‐Ru Wang, Ruize Zhang, Daowen Wang, Yong Wang, Zheng Qing Fu   +4 more
wiley   +1 more source

Taking Advantage of the Selectivity of Histone Deacetylases and Phosphodiesterase Inhibitors to Design Better Therapeutic Strategies to Treat Alzheimer's Disease. [PDF]

Front Aging Neurosci, 2019
Cuadrado-Tejedor M, Pérez-González M, García-Muñoz C, Muruzabal D, García-Barroso C, Rabal O, Segura V, Sánchez-Arias JA, Oyarzabal J, Garcia-Osta A.   +9 more
europepmc   +1 more source

Rolipram, a Phosphodiesterase-4-Selective Inhibitor, Promotes the Survival of Cultured Rat Dopaminergic Neurons.

, 1997
Nobuyuki Yamashita, Akiko Hayashi, Jun Baba, Aiko Sawa   +3 more
openalex   +1 more source

Xanthine Derivative KMUP‐3 Alleviates Periodontal Bone Resorption by Inhibiting Osteoclastogenesis and Macrophage Pyroptosis

Journal of Periodontal Research, EarlyView.
This study reveals that our self‐developed xanthine derivative, KMUP‐3, suppresses osteoclastogenesis, inflammation, and pyroptosis by inhibiting the NLRP3 inflammasome. It also alleviates periodontal bone loss in periodontitis rats, highlighting its potential as a novel therapeutic option for periodontitis.
Shang‐En Huang, Kai‐Fang Hu, Meng‐Xuan Lin, Ching‐Jiunn Tseng, Bin‐Nan Wu, Zen‐Kong Dai, Jong‐Hau Hsu, Jwu‐Lai Yeh   +7 more
wiley   +1 more source

Potential synergistic effect of phosphodiesterase inhibitors with chemotherapy in lung cancer. [PDF]

J Cancer, 2017
Domvri K, Zarogoulidis K, Zogas N, Zarogoulidis P, Petanidis S, Porpodis K, Kioseoglou E, Hohenforst-Schmidt W.   +7 more
europepmc   +1 more source