High energy-charged cell factory for heterologous protein synthesis [PDF]
Overexpression of gluconeogenic phosphoenolpyruvate carboxykinase (PCK) under glycolytic conditions enables Escherichia coli to maintain a greater intracellular ATP concentration and, consequently, to up-regulate genes for amino acid and nucleotide ...
Hye Jung Kim+3 more
core +1 more source
Our previous studies demonstrated that the key gluconeogenic enzyme fructose-1,6-bisphosphatase is secreted when Saccharomyces cerevisiae are starved of glucose for a prolonged period of time.
Bennett J. Giardina, H. Chiang
semanticscholar +1 more source
Tumour Cell Size Control and Its Impact on Tumour Cell Function
The regulatory mechanism of the size of tumour cells and its impact on the functions of tumour cells, as well as a summary of potential therapeutic targets for the corresponding mechanisms. ABSTRACT Cell size is an important component of cell morphological characteristics.
Min Zhou, Mei Zhou, Yang Jin
wiley +1 more source
Betaine supplementation in maternal diet modulates the epigenetic regulation of hepatic gluconeogenic genes in neonatal piglets. [PDF]
In this study, gestational sows were fed control or betaine-supplemented diets (3 g/kg) throughout the pregnancy, and the newborn piglets were used to elucidate whether maternal dietary betaine affected offspring hepatic gluconeogenic genes through ...
Demin Cai+6 more
doaj +1 more source
A generalized stoichiometric model of C3, C2, C2+C4, and C4 photosynthetic metabolism. [PDF]
The goal of suppressing photorespiration in crops to maximize assimilation and yield is stimulating considerable interest among researchers looking to bioengineer carbon-concentrating mechanisms into C3 plants.
Ap Rees+7 more
core +1 more source
Polo‐like kinases and UV‐induced skin carcinogenesis: What we know and what's next
The polo‐like kinase (PLK) family plays distinct and critical roles in the regulation of cell cycle progression, and its dysregulation has been implicated in various cancers. Ultraviolet (UV) radiation is a well‐established environmental factor in the development of skin cancer.
Tanya Jaiswal+3 more
wiley +1 more source
Effect of Simulated Microgravity on the Activity of Regulatory Enzymes of Glycolysis and Gluconeogenesis in Mice Liver [PDF]
Gravity supports all the life activities present on earth. Microgravity environments have effect on the biological functions and physiological status of an individual.
Adaikkappan Periyakaruppan, .+4 more
core +1 more source
Inflammation is vital for defence against injury and infection, but excessive inflammation can lead to tissue damage and disease. The central nervous system (CNS) helps regulate immune responses through neuroendocrine pathways, such as the hypothalamic–pituitary–adrenal axis and the anti‐inflammatory reflex, which limit systemic inflammation.
Evelin C. Cárnio+5 more
wiley +1 more source
Computational and Pharmacological Evaluation of Carveol for Antidiabetic Potential
BackgroundCarveol is a natural drug product present in the essential oils of orange peel, dill, and caraway seeds. The seed oil of Carum Carvi has been reported to be antioxidant, anti-inflammatory, anti-hyperlipidemic, antidiabetic, and hepatoprotective.
Muhammad Shabir Ahmed+3 more
doaj +1 more source
Ancestral light and chloroplast regulation form the foundations for C4 gene expression. [PDF]
C4 photosynthesis acts as a carbon concentrating mechanism that leads to large increases in photosynthetic efficiency. The C4 pathway is found in more than 60 plant lineages1 but the molecular enablers of this evolution are poorly understood.
Boursnell, Chris+5 more
core +2 more sources