Results 101 to 110 of about 29,850 (257)

Five nuclear protein-coding markers for establishing a robust phylogenetic framework of niphargid crustaceans (Niphargidae: Amphipoda) and new molecular sequence data

Data in Brief, 2019
The data presented here includes selection of 5 successfully amplified protein-coding markers for inferring phylogenetic relationships of the family of amphipod crustaceans Niphargidae. These markers have been efficiently amplified from niphargid samples
Ajda Moškrič, Rudi Verovnik
doaj   +1 more source

Mitochondrial Phosphoenolpyruvate Carboxykinase Regulates Metabolic Adaptation and Enables Glucose-Independent Tumor Growth [PDF]

, 2015
Cancer cells adapt metabolically to proliferate under nutrient limitation. Here we used combined transcriptional-metabolomic network analysis to identify metabolic pathways that support glucose-independent tumor cell proliferation.
Artyomov, Maxim N., Avizonis, Daina, Blagih, Julianna, Bridon, Gaëlle, Choinière, Luc, Coelho, Paula P., Elder, Douglas J E, Flynn, Breanna R., Gingras, Marie Claude, Griss, Takla, Jones, Russell G., Loginicheva, Ekaterina, Ntimbane, Thierry, Pause, Arnim, Raissi, Thomas C., Samborska, Bozena, Sergushichev, Alexey, Tavaré, Jeremy M., Thomas, Elaine C., Vincent, Emma E.   +19 more
core   +2 more sources

Proximal Tubule‐Specific Genetic Deficiency of PPARα Worsens Systemic Lipid and Glucose Metabolism During Fasting

The FASEB Journal, Volume 40, Issue 1, 15 January 2026.
Proximal tubule‐specific PPARα knockout mouse (PPARαΔKPT) showed decreased lipid and glucose metabolism in the kidney during fasting. Metabolism in the other organs was increased, presumably as a means of compensating for the impaired kidney metabolism.
Daiki Aomura, Takayuki Nimura, Kosuke Yamaka, Yosuke Yamada, Makoto Harada, Takero Nakajima, Takefumi Kimura, Koji Hashimoto, Hiroyuki Kanno, Motoko Yanagita, Frank J. Gonzalez, Naoki Tanaka, Yuji Kamijo   +12 more
wiley   +1 more source

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

FEBS Open Bio, Volume 16, Issue 1, Page 199-221, January 2026.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti, Bruna Lopes Correia, Francielle Cristina Nakamura Manicardi, Nairana Mithieli de Queiroz Eskuarek Melo, Vanesa de Oliveira Pateis, Jurandir Fernando Comar, Anacharis Babeto de Sá‐Nakanishi, Adelar Bracht, Lívia Bracht   +8 more
wiley   +1 more source

Ischaemic and metabolic treatment of hepatic tumours [PDF]

, 1988
For treatment of malignancies, physical and metabolic differences between tumour cells and host cells have guided the development of new approaches.
Ahrén, B, Bengmark, S
core   +3 more sources

Adenylosuccinate Synthase 1 Deficiency Improves Energy Metabolism by Promoting Adipose Tissue Re‐esterification via Glycerol Kinase Upregulation

Advanced Science, Volume 13, Issue 1, 5 January 2026.
Working model of Adss1‐mediated regulation of energy metabolism in adipose tissue. In beige adipocytes, Adss1 interacts with HDAC3 in the cytoplasm, and its loss reduces nuclear HDAC3 while increasing cytosolic fractions. This redistribution suppresses HDAC activity and enhances H3K27 acetylation at the Gk promoter, leading to transcriptional ...
Jingjing Sun, Miriayi Alimujiang, Wenfei Li, Shuqin Chen, Yingying Su, Tingting Hu, Xuhong Lu, Yafen Ye, Ningning Bai, Fan Hu, Xiaoya Li, Rongrong Xu, Jun Xu, Jiarui Zhao, Yan Lu, Xiaojing Ma, Ying Yang   +16 more
wiley   +1 more source

Comparative ubiquitinome analysis reveals the roles of protein ubiquitination in the heat stress response from Metarhizium robertsii

Applied and Environmental Microbiology
Protein ubiquitination plays a vital role in the stress response of diverse filamentous fungi. However, few reports are available on fungal insect pathogens, including Metarhizium.
Jueping Song, Ali Raza, Hanyuan Chen, Guangshuo Li, Bo Huang, Zhangxun Wang   +5 more
doaj   +1 more source

Critical roles of endogenous glucocorticoids for disease tolerance in malaria

, 2019
During malaria, the hypothalamic-pituitary-adrenal (HPA) axis is activated and glucocorticoid (GC) levels are increased, but their essential roles have been largely overlooked.
De Bosscher, Karolien, Opdenakker, Ghislain, Van den Steen, Philippe E., Vandermosten, Leen, Vanhorebeek, Ilse   +4 more
core   +1 more source

Macrophage phenotype in response to ECM bioscaffolds [PDF]

, 2017
Macrophage presence and phenotype are critical determinants of the healing response following injury. Downregulation of the pro-inflammatory macrophage phenotype has been associated with the therapeutic use of bioscaffolds composed of extracellular ...
Badylak, Stephen F, Bartolacci, Joseph G., Brown, Bryan N., Cramer, Madeline C., Dziki, Jenna L., Huleihel, Luai, LoPresti, Samuel T., Rausch, Theresa, Scarritt, Michelle E., Swinehart, Ilea T., Vorobyov, Tatiana, White, Lisa J.   +11 more
core   +2 more sources

Ancestral light and chloroplast regulation form the foundations for C4 gene expression. [PDF]

, 2016
C4 photosynthesis acts as a carbon concentrating mechanism that leads to large increases in photosynthetic efficiency. The C4 pathway is found in more than 60 plant lineages1 but the molecular enablers of this evolution are poorly understood.
Boursnell, Chris, Burgess, Steven J, Granero-Moya, Ignasi, Grangé-Guermente, Mathieu J, Hibberd, Julian M, Terry, Matthew J   +5 more
core   +2 more sources