Results 31 to 40 of about 41,567 (281)
Existing types of muscles differ not only structurally, but also metabolically (direction of energy exchange, choice of biosubstrates, dependence on the action of mediators, hormones, etc.).
G. Stepanov+3 more
doaj +1 more source
Phosphoenolpyruvate carboxykinase. II. Hormonal controls
Richard W. Hanson+3 more
openalex +4 more sources
The possible role of Phosphoenolpyrovate Carboxykinase (PEPCKin protein content of chickpea seeds (Cicer arietinum L [PDF]
Phosphoenolpyruvate Carboxykinase (PEPCK) has been shown to be present in plants andanimals, playing different metabolic roles in different tissues. The basic role of this enzyme is itscontribution in the gluconeogenesis pathway.
Maria Beihaghi+4 more
doaj +1 more source
The NADPH oxidase NOX4 regulates redox and metabolic homeostasis preventing HCC progression
Loss of NOX4 in HCC tumor cells induces metabolic reprogramming in a Nrf2/MYC‐dependent manner to promote HCC progression. Abstract Background and Aims The NADPH oxidase NOX4 plays a tumor‐suppressor function in HCC. Silencing NOX4 confers higher proliferative and migratory capacity to HCC cells and increases their in vivo tumorigenic potential in ...
Irene Peñuelas‐Haro+14 more
wiley +1 more source
Genetic variability in exon 9 of PEPCK-M gene in different strains of chickens using PCR-RFLP method [PDF]
Phosphoenolpyruvate carboxykinase (PEPCK) catalyzes the first step of the gluconeogenesis cycle. There are two isozymes forms of this enzyme, cytosolic phosphoenolpyruvate carboxykinase (PEPCK-C) and mitochondrial phosphoenolpyruvate carboxykinase (PEPCK-
Zohreh Yousefi+2 more
doaj +1 more source
O-GlcNAcylated p53 in the liver modulates hepatic glucose production
p53 regulates signalling pathways involved in metabolic homeostasis. Here the authors show that O-GlcNAcylation of p53 in the liver plays a key role in the physiological regulation of glucose homeostasis, potentially via controlling the expression of the
Maria J. Gonzalez-Rellan+42 more
doaj +1 more source
Phosphoenolpyruvate carboxykinase deficiency [PDF]
Inborn errors of 3 of the 4 enzymes specific for gluconeogenesis are known. The present report describes a deficiency of the 4th enzyme phosphoenolpyruvate carboxykinase (PEP-CK). characterized by severe hypoglycemia and extreme fatty changes of liver and kidney.
F A Hommes, J D Elema, C Bendien
openaire +2 more sources
Time-resolved crystallography of biomolecules in action has advanced rapidly as methods for serial crystallography have improved, but the large number of crystals and the complex experimental infrastructure that are required remain serious obstacles to ...
Jonathan A. Clinger+4 more
doaj +1 more source
Compensatory Increase of Serum Hepassocin Protects Hyperthyroidism-Induced Hepatic Dysfunction
Hepatic dysfunction is commonly observed in subjects with hyperthyroidism. Hepassocin is a hepatokine playing an important role in metabolic diseases and exhibiting a hepatic protective effect.
Chih-Chen Wang+6 more
doaj +1 more source
Biological Evaluation of a Mitochondrial Phosphoenolpyruvate Carboxykinase Inhibitor
Phosphoenolpyruvate carboxykinase (PEPCK) is a key enzyme in gluconeogenesis, catalyzingthe decarboxylation of oxaloacetate to phosphoenolpyruvate. [...]
Sergio Rodríguez-Arévalo+9 more
doaj +1 more source