Results 51 to 60 of about 10,168 (226)

Re‐evaluation of the risks to public health related to the presence of bisphenol A (BPA) in foodstuffs

EFSA Journal, Volume 21, Issue 4, April 2023., 2023
Abstract In 2015, EFSA established a temporary tolerable daily intake (t‐TDI) for BPA of 4 μg/kg body weight (bw) per day. In 2016, the European Commission mandated EFSA to re‐evaluate the risks to public health from the presence of BPA in foodstuffs and to establish a tolerable daily intake (TDI). For this re‐evaluation, a pre‐established protocol was
EFSA Panel on Food Contact Materials, Enzymes and Processing Aids (CEP), Claude Lambré, José Manuel Barat Baviera, Claudia Bolognesi, Andrew Chesson, Pier Sandro Cocconcelli, Riccardo Crebelli, David Michael Gott, Konrad Grob, Evgenia Lampi, Marcel Mengelers, Alicja Mortensen, Gilles Rivière, Vittorio Silano (until 21 December 2020†), Inger‐Lise Steffensen, Christina Tlustos, Laurence Vernis, Holger Zorn, Monika Batke, Margherita Bignami, Emanuela Corsini, Rex FitzGerald, Ursula Gundert‐Remy, Thorhallur Halldorsson, Andrew Hart, Evangelia Ntzani, Eugenio Scanziani, Henri Schroeder, Beate Ulbrich, Dina Waalkens‐Berendsen, Detlef Woelfle, Zainab Al Harraq, Katleen Baert, Maria Carfì, Anna F Castoldi, Cristina Croera, Henk Van Loveren   +37 more
wiley   +1 more source

Identification of vicinal thiols of phosphoenolpyruvate carboxykinase (GTP).

Journal of Biological Chemistry, 1993
Phosphoenolpyruvate carboxykinase (PEPCK) from the cytosol of rat liver has 13 cysteines, at least one of which (Cys288) is known to be very reactive and critical for catalytic activity (Lewis, C. T., Seyer, J. M., and Carlson, G. M. (1989) J. Biol. Chem. 264, 27-33).
C T Lewis, Gerald M. Carlson, Jerome M. Seyer, R G Cassell   +3 more
openaire   +3 more sources

Illegitimate recombination: An efficient method for random mutagenesis in Mycobacterium avium subsp. hominissuis

BMC Microbiology, 2012
Background The genus Mycobacterium (M.) comprises highly pathogenic bacteria such as M. tuberculosis as well as environmental opportunistic bacteria called non-tuberculous mycobacteria (NTM).
Khattak Faisal, Kumar Ashutosh, Kamal Elisabeth, Kunisch Ralph, Lewin Astrid   +4 more
doaj   +1 more source

Induction of mRNA for phosphoenolpyruvate carboxykinase (GTP) by dexamethasone in cultured rat hepatocytes requires on-going protein synthesis. [PDF]

Biochemical Journal, 1987
V. Nebes, S. Morris
semanticscholar   +2 more sources

Untersuchungen zur Rolle der Phosphoenolpyruvat-Carboxykinase und des NADP+-Malat-Enzyms in der filamentösen Phaeophycee Ectocarpus siliculosus [PDF]

, 2003
In der filamentösen Braunalge Ectocarpus siliculosus liegen die Enzyme Phosphoenolpyruvat-Carboxykinase (PEPCK) und das NADP+-Malat-Enzym in hohen Aktivitäten vor. Die Beteiligung beider Enzyme an einem für die Alge vorgeschlagenen C4/CAM-
Busch, Sylvia, Galland, Paul (Prof. Dr.)
core   +1 more source

Mitochondrial phosphoenolpyruvate carboxykinase (PEPCK-M) is a pro-survival, endoplasmic reticulum (ER) stress response gene involved in tumor cell adaptation to nutrient availability [PDF]

, 2018
Mitochondrial phosphoenolpyruvate carboxykinase (PEPCK-M), encoded by the nuclear PCK2 gene, links TCA cycle intermediates and glycolytic pools through the conversion of mitochondrial oxaloacetate into phosphoenolpyruvate.
Hyroššová, Petra, Méndez-Lucas, Andrés, Novellasdemunt, Laura, Perales Losa, Carlos, Viñals Canals, Francesc   +4 more
core   +1 more source

Phosphoenolpyruvate carboxykinase and the critical role of cataplerosis in the control of hepatic metabolism

Nutrition & Metabolism, 2005
Background The metabolic function of PEPCK-C is not fully understood; deletion of the gene for the enzyme in mice provides an opportunity to fully assess its function. Methods The gene for the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) (EC
Kalhan Satish C, Conlon Ronald A, Lepage David F, Yang Jianqi, Johnson Mark T, Hakimi Parvin, Reshef Lea, Tilghman Shirley M, Hanson Richard W   +8 more
doaj   +1 more source

The regulation of phosphoenolpyruvate carboxykinase (GTP) synthesis in rat kidney cortex. The role of acid-base balance and glucocorticoids.

Journal of Biological Chemistry, 1975
P. Iynedjian, F. Ballard, R. Hanson
semanticscholar   +2 more sources

Lack of association between PCK1 polymorphisms and obesity, physical activity, and fitness in European Youth Heart Study (EYHS) [PDF]

, 2010
Phosphoenolpyruvate carboxykinase-1 (PCK1) is the rate-limiting enzyme in the hepatic gluconeogenic pathway. Studies have shown that overexpression of Pck1 in mice results in obesity-related traits and higher levels of physical activity (PA).
Anders Grontved, Beale, Brage, Brito, Cao, Chang, Chang, Cole, Cole, Ekelund, Ekelund, Franckhauser, Franckhauser, Gloria-Bottini, Goodpaster, Gutin, Hakimi, Hansen, Heard-Costa, Kang, Karani S. Vimaleswaran, Kristensen, Lane, Lee, Lindgren, Ludwig, Meyre, Nicholas J. Wareham, Oberkofler, Paul W. Franks, Rajas, Rees, Riddoch, Romeo, Rosella, Ruth J.F. Loos, Sardinha, Shin, Soren Brage, Tanner, Thorleifsson, Ulf Ekelund, Vimaleswaran, Wegner, Willer, Yu   +45 more
core   +1 more source

Mn2+-sensitive and -insensitive forms of phosphoenolpyruvate carboxykinase (GTP).

Journal of Biological Chemistry, 1981
Phosphoenolpyruvate carboxykinase (GTP) (EC 4.1.1.32) from rat liver cytosol is activated by micromolar concentrations of Mn2+ under conditions where GTP is present as the MgGTP complex and free Mg2+ is present in excess. The purified, homogeneous enzyme rapidly loses the ability to be activated by Mn2+ upon storage, incubation with oxidized ...
R I Brinkworth, R W Hanson, Vern L. Schramm, F A Fullin   +3 more
openaire   +3 more sources