Results 51 to 60 of about 5,315 (148)
BioMed Research International, Volume 2022, Issue 1, 2022., 2022 One of the globally common cancers is colorectal cancer (CRC). At present, a surgical approach remains a good option for CRC patients; however, 20% of surgically treated CRC patients experience metastasis. Currently, even the first‐line used drug, oxaliplatin, remains inadequate for treating metastatic CRC, and its side effect of neurotoxicity is a ...
Md Misbah +4 more
wiley +1 more source
Identification of vicinal thiols of phosphoenolpyruvate carboxykinase (GTP).
Journal of Biological Chemistry, 1993 Phosphoenolpyruvate carboxykinase (PEPCK) from the cytosol of rat liver has 13 cysteines, at least one of which (Cys288) is known to be very reactive and critical for catalytic activity (Lewis, C. T., Seyer, J. M., and Carlson, G. M. (1989) J. Biol. Chem. 264, 27-33).
C T Lewis +3 more
openaire +3 more sources
Journal of Biological Chemistry, 2009 The SIRT1 activators isonicotinamide (IsoNAM), resveratrol, fisetin, and butein repressed transcription of the gene for the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) (PEPCK-C).
Jianqi Yang +10 more
semanticscholar +1 more source
Journal of Biological Chemistry, 1975 P. Iynedjian, F. Ballard, R. Hanson
semanticscholar +2 more sources
Intestinal gluconeogenesis and glucose transport according to body fuel availability in rats [PDF]
J Physiol 566 (15/07/2005) 575-86, 2007 Intestinal hexose absorption and gluconeogenesis have been studied in relation to refeeding after two different fasting phases: a long period of protein sparing during which energy expenditure is derived from lipid oxidation (phase II), and a later phase characterized by a rise in plasma corticosterone triggering protein catabolism (phase III).
arxiv +1 more source
BMC Microbiology, 2012 Background The genus Mycobacterium (M.) comprises highly pathogenic bacteria such as M. tuberculosis as well as environmental opportunistic bacteria called non-tuberculous mycobacteria (NTM).
Khattak Faisal +4 more
doaj +1 more source
Nutrition & Metabolism, 2005 Background The metabolic function of PEPCK-C is not fully understood; deletion of the gene for the enzyme in mice provides an opportunity to fully assess its function. Methods The gene for the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) (EC
Kalhan Satish C +8 more
doaj +1 more source
Prolonging assembly through dissociation:A self assembly paradigm in microtubules [PDF]
Phys. Rev. E 83, 051904 (2011), 2009 We study a one-dimensional model of microtubule assembly/disassembly in which GTP bound to tubulins within the microtubule undergoes stochastic hydrolysis. In contrast to models that only consider a cap of GTP-bound tubulin, stochastic hydrolysis allows GTP-bound tubulin remnants to exist within the microtubule.
arxiv +1 more source
Mn2+-sensitive and -insensitive forms of phosphoenolpyruvate carboxykinase (GTP).
Journal of Biological Chemistry, 1981 Phosphoenolpyruvate carboxykinase (GTP) (EC 4.1.1.32) from rat liver cytosol is activated by micromolar concentrations of Mn2+ under conditions where GTP is present as the MgGTP complex and free Mg2+ is present in excess. The purified, homogeneous enzyme rapidly loses the ability to be activated by Mn2+ upon storage, incubation with oxidized ...
R I Brinkworth +3 more
openaire +3 more sources
Changes in hepatic messenger RNA for phosphoenolpyruvate carboxykinase (GTP) during development.
Proceedings of the National Academy of Sciences of the United States of America, 1978 Phosphoenolpyruvate carboxykinase (GTP) [GTP;oxaloacetate carboxy-lyase(transphosphorylating); EC 4.1.1.32] is absent in rat liver cytosol during fetal life and is synthesized initially at birth. De novo synthesis of the enzyme can be induced prematurely
J. Ruiz, R. Ingram, R. Hanson
semanticscholar +1 more source