Results 91 to 100 of about 31,695 (232)

Genome-Wide Identification of the Phosphoglycerate Kinases and Functional Analysis of GmPGK5 in Regulating Oil Accumulation in Soybean

Plants
Phosphoglycerate kinase (PGK) is a vital glycolytic enzyme that provides energy and carbon skeletons to support fatty acid synthesis. However, the PGK gene family has not been characterized in soybean (Glycine max), and its role in soybean oil ...
Kai Zhang, Fengjia Zhu, Xiuli Yue, Songnan Yang, Yajun Mo, Shancen Zhao, Junyi Gai, Yan Li   +7 more
doaj   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, Volume 16, Issue 6, Page 1132-1141, June 2026.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Role of Domain Interactions in the Collective Motion of Phosphoglycerate Kinase [PDF]

, 2013
Protein function is governed by the underlying conformational dynamics of the molecule. The experimental and theoretical work leading to contemporary understanding of enzyme dynamics was mostly restricted to the large-scale movements of single-domain ...
Fidy, Judit, Schay, Gusztáv, Osváth, Szabolcs, Herényi, Levente   +3 more
core   +1 more source

Extracellular Pgk1 or Its Derived Short Peptide Interacted with Membrane-Associated Enolase 2 Receptor: A Potential Therapy for ALS Motor Neuron Degeneration

Biomolecules
Amyotrophic lateral sclerosis (ALS) remains an intractable motor neuron (MN) disease with a growing patient population and few effective treatments. Here, we review how extracellular phosphoglycerate kinase 1 (ePgk1) improves neurite outgrowth of MNs ...
Bing-Chang Lee, Juey-Jen Hwang, Huai-Jen Tsai   +2 more
doaj   +1 more source

Decoding Undesirable Inflammatory Responses of Nucleic Acid‐Delivering Lipid Nanoparticles

Advanced Science, Volume 13, Issue 33, 15 June 2026.
Lipid nanoparticles (LNPs) enable efficient nucleic acid delivery, but their immunogenicity is a double‐edged sword. This review explores LNP‐driven innate and adaptive immunity, covering lipid components, endosomal escape, and nucleic acid sensing.
Ruimin Hu, Yin Dou, Chenwen Li, Yuying Mu, Huiying Ouyang, Wenhao Shen, Jianxiang Zhang   +6 more
wiley   +1 more source

Integrated metabolome, proteome, and transcriptome analysis explored the molecular mechanism of phosphoglycerate kinase 1 and pyruvate kinase M2 characterizing the postmortem meat quality

Food Frontiers
Phosphoglycerate kinase 1 (PGK1) and pyruvate kinase M2 (PKM2) have been identified as the postmortem meat quality biomarkers. However, the precise molecular mechanism through which they affect and regulate the development of meat quality remains unclear.
Caiyan Huang, Can Xiang, Fangzhou Wang, Christophe Blecker, Zhenyu Wang, Li Chen, Dequan Zhang   +6 more
doaj   +1 more source

Quantitative proteomics analysis of varicose veins: Identification of a set of differentially expressed proteins related to ATP generation and utilization

Kaohsiung Journal of Medical Sciences, 2013
Although morphological and anatomical studies indicate that varicose veins are characterized by venous wall weakening and subendothelial fibrosis, the exact underlying biochemical mechanism of their development remains unknown.
Chao-Jen Kuo, Shih-Shin Liang, Edward Hsi, Shyh-Horng Chiou, Sin-Daw Lin   +4 more
doaj   +1 more source

Hydroxypyruvate Reductase 1 and Plastidial Glycolate/Glycerate Transporter 1 Connect Photorespiration With Plant Immunity

Plant, Cell &Environment, EarlyView.
Xiaotong Jiang, Sheng Yang He, Jianping Hu   +2 more
wiley   +1 more source

Optimizing Pichia Pastoris Cell‐Free Protein Synthesis to Improve Economics

Biotechnology and Bioengineering, Volume 123, Issue 6, Page 1708-1720, June 2026.
ABSTRACT Cell‐free protein synthesis (CFPS) is a powerful and versatile platform that supports a wide range of applications, from fundamental studies of the genetic code to scalable and rapid protein production. The recently developed Pichia pastoris CFPS combines advantages of both prokaryotic and eukaryotic systems, including a rapid growth rate ...
Rui Wu, Igor Koop, Gavin Murugan, Thagshanen Thillairajah, Karen M. Polizzi   +4 more
wiley   +1 more source

Hierarchic finite level energy landscape model: To describe the refolding kinetics of phosphoglycerate kinase

, 2006
One of the most intriguing predictions of energy landscape models is the existence of non-exponential protein folding kinetics caused by hierarchical structures in the landscapes.
Koehler, Gottfried (University of Vienna), Osvath, Szabolcs (Semmelweis Medical University Budapest, Hungary), Zavodszky, Péter (Biological Research Center of Szeged), Fidy, Judit (Semmelweis Medical University Budapest, Hungary)   +3 more
core   +1 more source