Results 71 to 80 of about 31,695 (232)

DETECTION OF ENOLASE AND PYRUVATE KINASE ENZYMES FROM FLUORIDE SENSITIVE AND FLUORIDE RESISTANCE STREPTOCOCCUS MUTANS BY USING PCR. [PDF]

open access: yesJournal of Bioscience and Applied Research
Background: This study aimed to detect enolase and pyruvate kinase, key metabolic enzymes in glycolysis, in fluoride-resistant and fluoride-sensitive Streptococcus mutans strains isolated from diabetic dental caries. Enolase catalyzes the conversion of 2-
Nuha Elhage   +2 more
doaj   +1 more source

Excessive training does not induce mitochondrial dysfunction or impair insulin signalling within skeletal muscle

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Three weeks of overtraining in trained endurance athletes reduced exercise performance without impairing glucose tolerance. In skeletal muscle, overtraining was associated with increased expression of lipid metabolism‐related proteins, enhanced mitochondrial biogenesis and preserved insulin signalling, despite elevated oxidative ...
Geneviève J. DesOrmeaux   +7 more
wiley   +1 more source

Phosphoglycerate kinase 1 as a therapeutic target in neurological disease [PDF]

open access: yes
Phosphoglycerate kinase 1 (PGK1) is a highly conserved enzyme that catalyzes the initial ATP-producing step in glycolysis. Improving cellular energy production by increasing PGK1 activity may be beneficial in multiple neurological conditions where cell ...
McHale-Owen, Harriet   +3 more
core   +1 more source

Phosphoproteomic Reveals That Phosphoglycerate Kinase 2 Suppresses Hypoxanthine Accumulation in Broiler

open access: yesFood Frontiers
Recent studies have found that the amount and proportion of meat flavor–related metabolites differ among different parts of muscle, which is partly attributed to their diverse myofiber type composition.
Manting Ma   +6 more
doaj   +1 more source

Stage‐Specific Metabolic and Proteomic Dynamics Underlying Ripening and Quality Formation in Tropical Evergreen Pomegranate

open access: yeseFood, Volume 7, Issue 4, August 2026.
Integrated multi‐omics reveals that pomegranate ripening between 90 and 130 days drives optimal sugar‐acid balance and pigmentation via coordinated regulation of phenylpropanoid, flavonoid, and carbohydrate metabolism pathways. ABSTRACT Pomegranate fruit development involves coordinated physiological, metabolic, and proteomic changes shaping coloration
Yawen Zhang   +6 more
wiley   +1 more source

Pharmacogenetic CYP2B6 variants affect steroid hormone metabolism in human breast cancer cells

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 7, Page 2075-2084, July 2026.
Common genetic CYP2B6 variants correlate with adverse breast cancer outcome. The oestrogen metabolites estriol and 16‐epiestriol, which are formed downstream of CYP2B6‐catalysed 16α/β‐hydroxytestosterone, may be linked to elevated breast cancer risk and might increase due to the demonstrated CYP2B6 variants‐related metabolic shifts.
Marco Hoffmann   +5 more
wiley   +1 more source

Temporal changes in phosphoglycerate kinase coding sequences: a quantitative measure

open access: yes, 2003
The ratio of the average of the square of the number of the nucleotides to that of the random sequence of the same strand bias is proposed as a quantitative measure of evolution in some coding DNA sequences.
Sujay Chattopadhyay   +1 more
core  

Crystallization and preliminary X-ray crystallographic studies of phosphoglycerate kinase from Thermus caldophilus

open access: yes, 2003
We report the purification and crystallization of phosphoglycerate kinase from Thermus caldophilus (Tca). The enzyme crystallizes in the P212121 space group (cell dimensions a = 65.1, b = 71.3, c = 80.2 ?), with one molecule in the asymmetric unit.
T Y Kim   +19 more
core   +1 more source

Glycerate kinase of the hyperthermophilic archaeon Thermoproteus tenax: new insights into the phylogenetic distribution and physiological role of members of the three different glycerate kinase classes

open access: yesBMC Genomics, 2007
Background The presence of the branched Entner-Doudoroff (ED) pathway in two hyperthermophilic Crenarchaea, the anaerobe Thermoproteus tenax and the aerobe Sulfolobus solfataricus, was suggested.
Siebers Bettina   +3 more
doaj   +1 more source

In silico prediction and structural characterization of multifunctional bioactive peptides released from olive proteins

open access: yesJournal of the Science of Food and Agriculture, Volume 106, Issue 9, Page 5463-5482, July 2026.
Abstract BACKGROUND Olive (Olea europaea L.) byproducts, such as seeds and leaves, are abundant agro‐industrial residues and represent underexplored protein sources with potential health relevance. However, the repertoire of bioactive peptides that may be released from olive proteins during gastrointestinal digestion remains poorly characterized.
Teresa Gonzalez‐de la Rosa   +6 more
wiley   +1 more source

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