Results 61 to 70 of about 31,695 (232)

Communication between the Nucleotide Site and the Main Molecular Hinge of 3-Phosphoglycerate Kinase

, 2016
3-Phosphoglycerate kinase is a hinge-bending enzyme with substrate-assisted domain closure. However, the closure mechanism has not been described in terms of structural details.
Judit Szabó (2299795), Andrea Varga (514916), Beáta Flachner (1436932), Mária Vas (1420432), Péter Závodszky (1420417), Peter V. Konarev (25366), Dmitri I. Svergun (25365)   +6 more
core   +1 more source

A Phosphoenzyme Intermediary in Phosphoglycerate Kinase Action

Journal of Biological Chemistry, 1971
Rabbit muscle phosphoglycerate kinase (EC 2.7.2.3) has been phosphorylated with γ-32P-ATP and then isolated by gel filtration. Phosphorylation was favored by the presence of phosphoenolpyruvate and a catalytic amount of pyruvate kinase, which appeared to remove ADP from the phosphorylation equilibrium.
C T, Walsh, L B, Spector
openaire   +2 more sources

Kinetic parameter prediction using neural networks identifies limitations to C4 photosynthesis

New Phytologist, EarlyView.
Schematic overview of the generation of artificial training data and training of neural networks in C4TUNE. Summary Kinetic models of photosynthesis enable time‐resolved predictions of traits related to this key process and provide the means to identify factors limiting photosynthesis.
Philipp Wendering, John Ferguson, Rudan Xu, Johannes Kromdijk, Zoran Nikoloski   +4 more
wiley   +1 more source

Endurance-training induced changes in skeletal muscle phosphoglycerate kinase of old Wistar rats

, 1991
Sufficiently intense, long-term, endurance training has been shown in several studies to induce a variety of adaptations in skeletal muscle, including a substantial restoration of the activities of several muscle enzymes which are known to be modified ...
White, Timothy P., Gafni, Ari, Zhou, Jian Q.   +2 more
core   +1 more source

Novel Drosophila model for parkinsonism by targeting phosphoglycerate kinase

, 2020
Patients with Parkinson’s disease (PD) show a common progressive neurodegenerative movement disorder characterized by rigidity, tremors, postural instability, and bradykinesia due to the loss of dopaminergic neurons in the substantia nigra, and is often ...
Yamaguchi, Masamitsu, Shinomoto, Makiko, Kasai, Takashi, M. Huynh, Anh, 1013693, Takahiko, Tokuda, 1013698, 1013699, Tokuda, Takahiko, 1013700, Mizuno, Toshiki, 1013701, 1013694, 1013695, 1013696, 1013697, Yumiko, Nakao-Azuma, Shimizu, Joe, Yoshida, Hideki, 1013702   +19 more
core   +1 more source

Systemic and Local Regulation of Root Growth by Vascular Trehalose 6‐Phosphate is Correlated With Re‐allocation of Primary Metabolites Between Shoots and Roots

Plant, Cell &Environment, EarlyView.
ABSTRACT Trehalose 6‐phoshpate (Tre6P) is a key signalling molecule that reflects carbon status and integrates it with developmental decision making. Tre6P has been demonstrated to regulate various developmental processes, including vegetative growth, shoot branching, flowering, and root branching.
Moritz Göbel, Jacqueline Foster, Philipp Westhoff, Noemi Skorzinski, Hannah L. Lepper, Maria F. Njo, Markus Schmid, Tom Beeckman, Miloš Tanurdžić, Anna Amtmann, Franziska Fichtner   +10 more
wiley   +1 more source

Organothallium(III) reagents for modification of biomacromolecules:irreversible labelling of phosphoglycerate kinase from rabbit muscle

, 1987
Organothallium(III) reagents, by analogy with organomercurials, have been found to rapidly label phosphoglycerate kinase from rabbit muscle. By use of a radio-labelled version of p-methylphenylthallium(III) bis-trifluoroacetate (MPT) the inhibition was ...
Bunni, Marlene A., Baindur, Swati R., Douglas, Kenneth T.; id_orcid, Drake, Alex F.   +3 more
core   +1 more source

Activating Silent Glycolysis Bypasses in Escherichia coli

BioDesign Research, 2022
All living organisms share similar reactions within their central metabolism to provide precursors for all essential building blocks and reducing power. To identify whether alternative metabolic routes of glycolysis can operate in E.
Camillo Iacometti, Katharina Marx, Maria Hönick, Viktoria Biletskaia, Helena Schulz-Mirbach, Beau Dronsella, Ari Satanowski, Valérie A. Delmas, Anne Berger, Ivan Dubois, Madeleine Bouzon, Volker Döring, Elad Noor, Arren Bar-Even, Steffen N. Lindner   +14 more
doaj   +1 more source

Site-directed mutagenesis of histidine 62 in the ‘basic patch’ region of yeast phosphoglycerate kinase

, 1989
Site-directed mutagenesis has been used to produce a mutant form of yeast phosphoglycerate kinase (PGK) in which the ‘basic patch’ residue His 62 has been replaced by a glutamine residue. Using 1H-NMR spectroscopy, it was found that 3-phosphoglycerate (3-
Hall, Len, Herman C. Watson, Fairbrother, Wayne J., Robert J.P. Williams, Philip A. Walker, Len Hall, Jennifer A. Littlechild, Wayne J. Fairbrother, Walker, Philip A., Watson, Herman C., Williams, Robert J.P., Littlechild, Jennifer A.   +11 more
core   +1 more source

Regulation of phase separation and antiviral activity of Cactin by glycolytic enzyme PGK via phosphorylation in Drosophila

mBio
Liquid–liquid phase separation (LLPS) plays a crucial role in various biological processes in eukaryotic organisms, including immune responses in mammals.
Dongchao Chen, Chang Shi, Wen Xu, Qiqi Rong, Qingfa Wu   +4 more
doaj   +1 more source