Results 121 to 130 of about 18,679,675 (294)
Targeting epithelial-mesenchymal transition pathway in hepatocellular carcinoma [PDF]
Clinical and Molecular Hepatology, 2020 Jaewhan Song
doaj +1 more source
Revista CientíficaThis study aimed to investigate the modulatory effects of vitamin C and vitamin E on fluorosis-induced gene expression alterations in oxidative stress (Glutathione Peroxidase 1, Neutrophil Cytosolic Factor 1, Superoxide Dismutase 1), apoptosis (Caspase ...
Ahmet Cihat–Öner +5 more
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International Journal of Cancer, EarlyView.ABSTRACT Early diagnosis remains challenging, recurrence rates remain high, and platinum resistance frequently develops in ovarian cancer (OC), collectively representing major barriers to long‐term patient survival. DNA methylation (DNAm), as a relatively stable yet dynamically modifiable epigenetic signature, can capture alterations in tumor states ...
Min Xing +6 more
wiley +1 more source
Phosphoinositide-3 kinase-Akt pathway controls cellular entry of Ebola virus.
PLoS Pathogens, 2008 The phosphoinositide-3 kinase (PI3K) pathway regulates diverse cellular activities related to cell growth, migration, survival, and vesicular trafficking. It is known that Ebola virus requires endocytosis to establish an infection.
Mohammad F Saeed +4 more
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International Journal of Gynecology &Obstetrics, EarlyView.Abstract Objective To investigate the role of ST3 β‐galactoside α‐2,3‐sialyltransferase 1 (ST3Gal1) and vascular endothelial growth factor receptor 2 (VEGF‐R2) in endometrioid‐type epithelial ovarian cancer (E‐OC) because aberrant α2,3‐sialylation mediated by ST3Gal1 and VEGF‐R2‐related angiogenesis is linked with tumor progression. Methods ST3Gal1 and
Wei‐Ting Chao +5 more
wiley +1 more source
Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials
iNew Medicine, EarlyView.ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong +5 more
wiley +1 more source
, 2007 This thesis is focused on the characterization of new protein kinases from plants. Here, I show that the Arabidopsis UbDK[gamma]4 and UbDK[gamma]7 (ubiquitin-like domain kinases), which were originally identified as putative phosphatidylinositol 4 ...
Galvao, Rafaelo Marques
core
Zhongguo aizheng zazhi, 2020 Background and purpose: The 6-phosphofructo-2-kinase 3 (PFKFB3) is closely related to tumorigenesis and tumor development, and has important regulatory effects on the biological behavior of tumor cells.
刘 鹏 +6 more
doaj
The Endothelial CXCR Family in Vascular Health and Disease
iNew Medicine, EarlyView.ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu +4 more
wiley +1 more source
Research Progress of Berberine in Kidney Disease: Targeting Mitochondria and Ferroptosis
iNew Medicine, EarlyView.This figure illustrates the model‐specific renoprotective mechanisms of berberine (BBR) across three major kidney diseases. From left to right, the diagram shows that BBR targets distinct core pathways depending on the pathological context: in diabetic nephropathy (DN), BBR activates AMPK to improve mitochondrial energy metabolism; in acute kidney ...
Liuqing Wang +3 more
wiley +1 more source