The Dark Side of Activated Phosphoinositide 3-Kinase-δ Syndrome 2: A Story Rewritten through FDG-PET. [PDF]
J Clin MedCatelli A +6 more
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Leptin protects chondrocytes by inhibiting autophagy via phosphoinositide 3 kinase/protein kinase B/mammalian target of rapamycin signaling pathway. [PDF]
HeliyonLi P, Jiang W, Yang Q, Lu Y, Zhang J.
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Erratum: Huang et al., "Phosphoinositide 3-Kinase Gamma Contributes to Neuroinflammation in a Rat Model of Surgical Brain Injury". [PDF]
J Neuroscieuropepmc +1 more source
Differential expression of phosphoinositide 3-kinase/protein kinase B and Toll-like receptor/nuclear factor kappa B signaling pathways in experimental obesity Wistar rat model. [PDF]
Open Life SciSong L, Li L.
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Zinc finger and broad-complex, tramtrack, and bric-a-brac domain containing 16 silencing attenuates bleomycin-induced pulmonary fibrosis in mice through inhibition of the phosphoinositide 3-kinase/protein kinase B/mammalian target of rapamycin pathway. [PDF]
CytojournalFang X, Wen X, Zhou L, Jiang Y, Wang L.
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The Phosphoinositide 3-Kinase Pathway
Science, 2002Phosphorylated lipids are produced at cellular membranes during signaling events and contribute to the recruitment and activation of various signaling components. The role of phosphoinositide 3-kinase (PI3K), which catalyzes the production of phosphatidylinositol-3,4,5-trisphosphate, in cell survival pathways; the regulation of gene expression and cell
L. Cantley
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Abstract Plants, yeast and animal cells contain phosphoinositide 3-kinase activities (PI3K), each of which is capable of transferring the terminal phosphate of ATP to the D-3 position of the inositol head groups of one or more of the substrates Ptdins, PtdIns4P, and PtdIns(4,5)P2 (see Chapter 1 and references therein).
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