Results 181 to 190 of about 37,565 (330)

Potential endogenous lipid ligands for the nuclear receptor transcription factor Steroidogenic Factor-1. [PDF]

Adv Biol Regul
Campbell AN, Blind RD.
europepmc   +1 more source

QSP Modeling Shows Pathological Synergism Between Insulin Resistance and Amyloid‐Beta Exposure in Upregulating VCAM1 Expression at the BBB Endothelium

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 561-571, March 2025.
ABSTRACT Type 2 diabetes mellitus (T2DM), characterized by insulin resistance, is closely associated with Alzheimer's disease (AD). Cerebrovascular dysfunction is manifested in both T2DM and AD, and is often considered as a pathological link between the two diseases.
Zengtao Wang, Vaishnavi Veerareddy, Xiaojiao Tang, Kevin J. Thompson, Sunil Krishnan, Krishna R. Kalari, Karunya K. Kandimalla   +6 more
wiley   +1 more source

Subcellular localization and phosphorylation of phosphoinositide-phospholipase C γ1 correlate with breast cancer invasiveness

, 2011
Marco Marchisio, Paola Lanuti, Laura Pierdomenico, Giuseppina Bologna, Giovanna Grifone, Stéphanie Pacella, Sebastianó Miscia   +6 more
openalex   +1 more source

Phytochemical‐Based Strategies for Lung Cancer: Clinical Insights Into Pleiotropic Molecular Signaling and Therapeutic Roles

Phytotherapy Research, EarlyView.
Lung cancer (LC) remains the leading cause of global cancer‐related death. Phytochemicals from medicinal plants are increasingly being considered as potential LC treatment agents due to their multi‐targeted action, safety, and accessibility. These have anticancer properties by regulating key molecular signaling pathways.
Md. Rezaul Islam, Abdur Rauf, Happy Akter, Md. Ibrahim Khalil Al‐Imran, Md. Naeem Hossain Fakir, Gazi Kaifeara Thufa, Umme Habiba, Karjin Nahar Riya, Md. Mahfuzur Rahman, Md Sadique Hussain, Hanan A. Ogaly, Abdullah S. M. Aljohani, Waleed Al Abdulmonem, Dorota Formanowicz, Marcello Iriti   +14 more
wiley   +1 more source

A computational framework for the investigation of phosphoinositide regulation. [PDF]

PLoS Comput Biol
Cheung HYF, Tantiwong C, Kale D, Gibbins JM, Watson SP, Heemskerk JWM, Sickmann A, Ahrends R, Dunster JL.   +8 more
europepmc   +1 more source

A New Phenotype–Genotype Correlation for FIG4 and Parkinson's Disease

Movement Disorders Clinical Practice, EarlyView.
Iro Boura, Panayiotis Mitsias, Sofia Erimaki, Efrosini Papadaki, Cleanthe Spanaki   +4 more
wiley   +1 more source

Cardiac disease in systemic sclerosis: Integrating pathobiology with clinical management

Rheumatology &Autoimmunity, EarlyView.
Abstract Systemic sclerosis (SSc) is a complex autoimmune disorder in which cardiovascular involvement remains a major determinant of morbidity and mortality. Cardiac injury in SSc results from the interplay of microvascular dysfunction, immune‐mediated inflammation, and progressive interstitial and replacement fibrosis, leading to myocardial disease ...
Henry Sutanto, Betty Rachma, Yuliasih
wiley   +1 more source

Editorial: Cell polarity: Trafficking and regulatory events that determine cell asymmetry

Frontiers in Cell and Developmental Biology, 2023
Andrés E. Zucchetti, James R. Goldenring, M. Cecilia Larocca   +2 more
doaj   +1 more source

Long-tailed class I myosins rely on tail-mediated phosphoinositide recognition for specific membrane recruitment. [PDF]

Cell Commun Signal
Rajendraprasad G, Kyriazi D, Franz P, Bader A, Erent M, Uta P, Preller M, Scholz T, Tsiavaliaris G.   +8 more
europepmc   +1 more source

Bombesin, neuromedin B and neuromedin C interact with a common rat pancreatic phosphoinositide-coupled receptor, but are differentially regulated by guanine nucleotides [PDF]

, 1991
Mahendran Sekar, Naomi Uemura, D.H. Coy, Basil I. Hirschowitz, Kenneth E.J. Dickinson   +4 more
openalex   +1 more source