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Phospholipases A in Trypanosomatids [PDF]
Phospholipases are a complex and important group of enzymes widespread in nature, that play crucial roles in diverse biochemical processes and are classified as A1, A2, C, and D. Phospholipases A1and A2activities have been linked to pathogenesis in various microorganisms, and particularly in pathogenic protozoa they have been implicated in cell ...
María Laura Belaunzarán +2 more
openaire +3 more sources
Phospholipase A1 (PLA1) is an enzyme that hydrolyzes phospholipids and produces 2-acyl-lysophospholipids and fatty acids. This lipolytic activity is conserved in a wide range of organisms but is carried out by a diverse set of PLA1 enzymes. Where their function is known, PLA1s have been shown to act as digestive enzymes, possess central roles in ...
Richmond, Gregory S., Smith, Terry K.
openaire +2 more sources
The effect of lipoprotein-associated phospholipase A2 deficiency on pulmonary allergic responses in Aspergillus fumigatus sensitized mice. [PDF]
BackgroundLipoprotein-associated phospholipase A2 (Lp-PLA2)/platelet-activating factor acetylhydrolase (PAF-AH) has been implicated in the pathogenesis of cardiovascular disease.
Fehrenbach, Melane L +8 more
core +2 more sources
Enzymatic Degumming of Rice Bran Oil Using Different Commercial Phospholipases and Their Cocktails
Rice bran oil is a highly nutritious vegetable oil, as it is rich in tocols and γ-oryzanol. Degumming is the first step in the vegetable oil refining process, and its main objective is the removal of phospholipids or gums. In the present study, enzymatic
Mayara S. Rodrigues +7 more
doaj +1 more source
Identification of caspase 3 motifs and critical aspartate residues in human Phospholipase D1b and Phopsholipase D2a [PDF]
Stimulation of mammalian cells frequently initiates phospholipase D-catalysed hydrolysis of phosphatidylcholine in the plasma membrane to yield phosphatidic acid (PA) a novel lipid messenger.
Ahn +43 more
core +1 more source
The bacterial pathogen Pseudomonas aeruginosa uses three type VI secretion systems (T6SSs) to drive a multitude of effector proteins into eukaryotic or prokaryotic target cells.
Sarah Wettstadt +3 more
doaj +1 more source
Plasmodium falciparum is an Apicomplexa responsible for human malaria, a major disease causing more than ½ million deaths every year, against which there is no fully efficient vaccine.
Serena Shunmugam +8 more
doaj +1 more source
Biofilm, proteinase and phospholipase production by Candida albicans isolates from a hospital in Thailand [PDF]
This study aimed to determine biofilm formation, and production of phospholipase and proteinase in 73 clinical isolates of Candida albicans. Biofilms formed in a 96-well plate were quantified by crystal violet staining.
Srisuda Pannanusorn +2 more
doaj
Pancreatic phospholipase A2 activity in acute pancreatitis: A prognostic marker for early identification of patients at risk [PDF]
Remarkably elevated levels of phospholipase A(2) (PLA(2)) are measurable in human blood samples in cases of acute pancreatitis. The source of the enzyme was first thought to be exclusively the pancreas, but now it is generally accepted that two ...
Aufenanger, Johannes +5 more
core +1 more source
For its replication within red blood cells, the malaria parasite depends on a highly active and regulated lipid metabolism. Enzymes involved in lipid metabolic processes such as phospholipases are, therefore, potential drug targets.
Paul-Christian Burda +12 more
doaj +1 more source

