Results 101 to 110 of about 321,900 (228)

Phospholipase A2 enzymes and the risk of atherosclerosis.

European Heart Journal, 2012
Certain members of the phospholipase A(2) superfamily of enzymes have established causal involvement in atherosclerosis, thus at least two groups of this family of enzymes have been considered potential candidates for the prevention of cardiovascular ...
R. Rosenson, E. Hurt-Camejo
semanticscholar   +1 more source

Phospholipase A2 structure/function, mechanism, and signaling1

Journal of Lipid Research, 2009
Tremendous advances in understanding the structure and function of the superfamily of phospholipase A2 (PLA2) enzymes has occurred in the twenty-first century.
John E. Burke, Edward A. Dennis
doaj   +1 more source

Lysophosphatidylcholine induces arachidonic acid release and calcium overload in cardiac myoblastic H9c2 cells

Journal of Lipid Research, 1999
Lysophosphatidylcholine (lyso-PC) and arachidonate are products of phosphatidylcholine hydrolysis by phospholipase A2. In this study, the modulation of arachidonate release by exogenous lyso-PC in rat heart myoblastic H9c2 cells was examined.
Leonard S. Golfman, Norman J. Haughey, Jason T. Wong, Jenny Y. Jiang, Douglas Lee, Jonathan D. Geiger, Patrick C. Choy   +6 more
doaj   +1 more source

Effect of probiotic supplementation on lipoprotein-associated phospholipase A2 in type 2 diabetic patients: a randomized double blind clinical controlled trial

Nutrition & Metabolism
Background It has been recently reported that lipoprotein-associated phospholipase A2 (Lp-PLA2) may predict the risk of cardiovascular disease. The effect of multi-strain probiotics on Lp-PLA2 in patients with type 2 diabetes is still not clear.
Salman Jaff, Mohammed Gubari, Sakineh Shab-Bidar, Kurosh Djafarian   +3 more
doaj   +1 more source

A Novel Phospholipase A2 Isolated from Palythoa caribaeorum Possesses Neurotoxic Activity

Toxins, 2019
Zoanthids of the genus Palythoa are distributed worldwide in shallow waters around coral reefs. Like all cnidarians, they possess nematocysts that contain a large diversity of toxins that paralyze their prey.
Miguel Cuevas-Cruz, Fernando Lazcano-Pérez, Ulises Hernández-Guzmán, Karen Helena Díaz de la Vega-Castañeda, Sergio A. Román-González, Norma A. Valdez-Cruz, Benjamín Velasco-Bejarano, Ana Laura Colín-González, Abel Santamaría, Saúl Gómez-Manzo, Jaime Marcial-Quino, Roberto Arreguín-Espinosa   +11 more
doaj   +1 more source

Activation of phospholipase D-2 by P2X7 agonists in rat submandibular gland acini

Journal of Lipid Research, 2002
Exogenous ATP stimulated phospholipase D (PLD), but not sphingomyelinase in rat submandibular gland (SMG) acini. PLD activation was dependent upon extracellular Ca2+ and did not involve intracellular Ca2+ mobilization or phosphoinositide-specific ...
Encarnación Pérez-Andrés, María Fernández-Rodriguez, Mónica González, Ana Zubiaga, Ainara Vallejo, Itxaso García, Carlos Matute, Stéphanie Pochet, Jean Paul Dehaye, Miguel Trueba, Aida Marino, Antonio Gómez-Muñoz   +11 more
doaj   +1 more source

Properties and Regulation of Cytosolic Phospholipase A2 *

Journal of Biological Chemistry, 1997
Membrane phospholipid is an important reservoir for the generation of bioactive mediators. Cellular phospholipases hydrolyze membrane phospholipid in a structurally specific manner releasing numerous lipid products that are responsible for transmitting ...
C. Leslie
semanticscholar   +1 more source

Activation of phospholipase C beta 2 by the alpha and beta gamma subunits of trimeric GTP-binding protein [PDF]

, 1993
Cotransfection assays were used to show that the members of the GTP-binding protein Gq class of alpha subunits could activate phospholipase C (PLC) beta 2.
Katz, Arieh, Simon, Melvin I., Wu, Dianqing   +2 more
core  

Variaciones en las actividades enzimáticas del veneno de la serpiente Bothrops atrox "jergón", de tres zonas geográficas del Perú Variation of the enzymatic activity of Bothrops atrox "jergon" snake venom from three geographic regions, Peru

Revista Peruana de Medicina Experimental y Salud Pública, 2012
Objetivos. Estudiar la variabilidad en la composición y actividades enzimáticas entre venenos de ejemplares adultos de Bothrops atrox. Materiales y métodos. Se emplearon venenos de serpientes adultas procedentes de Amazonas, Junín y Ucayali.
César Ortiz, Fanny Lazo, Candy Bellido, Edgar Gonzales, Armando Yarlequé   +4 more
doaj  

Noninvasive diagnosis of primary membranous nephropathy using phospholipase A2 receptor antibodies.

Kidney International, 2019
S. Bobart, A. D. De Vriese, A. Pawar, Ladan Zand, S. Sethi, Callen D. Giesen, J. Lieske, F. Fervenza   +7 more
semanticscholar   +1 more source