Results 161 to 170 of about 118,336 (250)

Activity of phospholipase A2 [PDF]

Gut, 1988
N C, Bird, A J, Goodman
openaire   +2 more sources

The many dimeric faces of Lys49 PLA2‐like proteins: Conformational plasticity and membrane binding drive functional dimer states

Protein Science, Volume 35, Issue 2, February 2026.
Abstract Lys49 secreted phospholipase A2‐like proteins (sPLA2s) are major myotoxins in viperid snake venoms, causing rapid muscle damage in envenomation. Beyond their clinical relevance, these small non‐catalytic proteins provide a model to study how quaternary structure and conformational dynamics enable catalysis‐independent membrane disruption ...
Diane C. A. Lima, Vinicius Firmino dos Santos, Bernardo Rassi, Richard J. Ward, Thereza A. Soares   +4 more
wiley   +1 more source

β2-Integrins regulate dendritic cells through nuclear deformation and activation of phospholipase A2 and DNA damage-inducible GADD34. [PDF]

J Biol Chem
Somermäki R, Harjunpää H, Cui Y, Walander A, Fagerholm SC.   +4 more
europepmc   +1 more source

Pulmonary Vascular Endothelial Cells in Lung Diseases: Mechanisms, Therapeutic Strategies, and Future Directions

Cell Proliferation, Volume 59, Issue 2, February 2026.
The pathogenic mechanisms of pulmonary vascular endothelial cells (VECs) in lung diseases and their multimodal therapeutic strategies. ABSTRACT Pulmonary vascular endothelial cells (VECs) are essential for the normal function of the lung, through maintaining vascular barrier integrity, regulating blood flow, and participating in inflammatory responses ...
Qianyue Liu, Hongshuai Zheng, Jing Liu, Ming Gao, Faquan Lin, Lin Liao   +5 more
wiley   +1 more source

The recombinant protein of scorpion venom phospholipase A2 exhibits potential anti-leishmanial activity. [PDF]

Sci Rep
Soltan-Alinejad P, Ramezani A, Asgari Q, Alipour H, Soltani A, Bahreini MS, Nikbakhtzadeh M, Azizi K.   +7 more
europepmc   +1 more source

Heart matters: How glucose‐ and lipid‐modulating drugs remodel epicardial adipose tissue accumulation, inflammatory patterns and browning

Diabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 878-894, February 2026.
Abstract Epicardial adipose tissue (EAT) is a metabolically active visceral fat depot located between the myocardium and the visceral pericardium, exerting direct paracrine and vasocrine effects on the heart and coronary vessels. Under physiological conditions, EAT supports myocardial energy metabolism and thermoregulation through fatty acid supply and
Elisabeth Heuboeck, Charnkamal Singh Bhogal, Markus Mandl   +2 more
wiley   +1 more source

Phospholipase A2 and Systemic-Immune Inflammation Index as Early Predictors of Neurotoxicity Induced by Acute Glufosinate Ammonium Poisoning: A Population-Based Case-Control Analysis. [PDF]

Emerg Med Int
Xue X, Wu X, Sun Z, Nie S, Huang C.
europepmc   +1 more source

Bee products as alternatives in the treatment of viral infections

Journal of the Science of Food and Agriculture, Volume 106, Issue 1, Page 33-54, 15 January 2026.
Abstract Medicines used in the treatment of viral infections usually reduce symptoms. There is a need to develop drugs that inhibit the viruses and do not merely relieve the symptoms. Natural bee products possess many pharmacological properties and are widely used in folk medicine. There are many studies on the antibacterial effects of bee products but
Michał Otręba, Łukasz Marek, Jerzy Stojko, Anna Rzepecka‐Stojko   +3 more
wiley   +1 more source

Cytosolic Phospholipase A2 Determines Intercellular Heterogeneity of Stress Granules and Chemotherapy Response. [PDF]

Cancer Discov
Redding A, Fonteneau G, Heinrich S, Gaida MM, Grabocka E.   +4 more
europepmc   +1 more source

Degradation of oxidized phospholipids by lysosomal phospholipase A2 regulates pulmonary fibrosis. [PDF]

Am J Physiol Lung Cell Mol Physiol
Kwak D, Ling S, Subbotina N, Shayman JA, Sisson TH, Kim KK.   +5 more
europepmc   +1 more source