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Phospholipase C: underrated players in microbial infections [PDF]
Frontiers in Cellular and Infection Microbiology, 2023 During bacterial infections, one or more virulence factors are required to support the survival, growth, and colonization of the pathogen within the host, leading to the symptomatic characteristic of the disease.
Vinayak Singh +6 more
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Phospholipase C is a novel regulator at the early stages of microspore embryogenesis in Nicotiana tabacum [PDF]
Plant Signaling & Behavior, 2022 Microspore transfers the developmental fate into embryogenesis in vitro regulated by determinant factors of stress-induced. However, the key regulators of microspore embryogenesis (ME) are still largely undiscovered to reveal the mechanism of cell fate ...
Pan Luo +7 more
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Phosphatidylcholine-Specific Phospholipase C as a Promising Drug Target [PDF]
Molecules, 2023 Phosphatidylcholine-specific phospholipase C (PC-PLC) is an enzyme that catalyzes the formation of the important secondary messengers phosphocholine and diacylglycerol (DAG) from phosphatidylcholine.
Chatchakorn Eurtivong +4 more
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Effects of phospholipase C inhibition on the regulation of membrane lipid metabolism in maize leaves [PDF]
Frontiers in Plant ScienceIntroductionPhospholipase C (PLC) is an enzyme that catalyzes the hydrolysis of glycerophospholipids and can be classified as phospholipase-specific PLC (PI-PLC) and non-specific PLC (NPC) depending on its specific substrate.MethodsIn this study ...
Yulei Wei +9 more
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Insights into the mechanism of phospholipid hydrolysis by plant non-specific phospholipase C [PDF]
Nature Communications, 2023 Non-specific phospholipase C (NPC) is a plant-specific phospholipid-hydrolyzing enzyme. Here, the authors define the molecular basis of how Arabidopsis NPC works, and provide new mechanistic insights into the members of phospholipase family.
Ruyi Fan +11 more
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Alopecia in a viable phospholipase C delta 1 and phospholipase C delta 3 double mutant. [PDF]
PLoS ONE, 2012 BACKGROUND: Inositol 1,4,5trisphosphate (IP(3)) and diacylglycerol (DAG) are important intracellular signalling molecules in various tissues. They are generated by the phospholipase C family of enzymes, of which phospholipase C delta (PLCD) forms one ...
Fabian Runkel +7 more
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Zhongguo youzhi, 2022 为了提高脱胶效率，以冷榨菜籽原油为原料，磷脂含量为指标，采用磷脂酶Lecitase Ultra和磷脂酶C复合酶法对冷榨菜籽油进行脱胶。采用单因素试验考察磷脂酶Lecitase Ultra反应时间、磷脂酶C反应时间、加水量、磷脂酶Lecitase Ultra添加量、磷脂酶C添加量、柠檬酸溶液添加量对脱胶油磷脂含量的影响，并通过响应面法优化脱胶条件。对优化的脱胶条件下所得到的脱胶油的理化指标进行了检测，并与国标一级压榨菜籽油进行了比较。结果表明：磷脂酶Lecitase ...
马云睿1，周力1，高盼1,2，胡传荣1,2，罗质1,2，何东平1,2MA Yunrui1, ZHOU Li1, GAO Pan1,2, HU Chuanrong1,2, LUO Zhi1,2, HE Dongping1,2
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Liang you shipin ke-ji, 2021 The enzymatic degumming process of crude corn oil using phospholipase C from Thielavia terrestris was studied.The key factors affecting the enzymatic degumming efficiency of crude corn oil,including enzyme dosage, volume ratio of NaOH to citric acid ...
HU Ting-ting +4 more
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PTEN regulates phospholipase D and phospholipase C [PDF]
Human Molecular Genetics, 2007 PTEN is an ubiquitously expressed tumor suppressor which plays a prominent role in the pathogenesis of many types of sporadic solid tumors, including breast cancer, as well as hematologic malignancies. Germline PTEN mutations cause 85% of Cowden syndrome (CS), characterized by a high risk of breast and thyroid cancers, and 65% of Bannayan-Riley ...
Charis Eng +3 more
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Crystal Structures of the Plant Phospholipase A1 Proteins Reveal a Unique Dimerization Domain
Molecules, 2022 Phospholipase is an enzyme that hydrolyzes various phospholipid substrates at specific ester bonds and plays important roles such as membrane remodeling, as digestive enzymes, and the regulation of cellular mechanism.
Yunseok Heo +8 more
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