Results 171 to 180 of about 18,826,497 (287)

Phospholipase C: Diverse functions in plant biotic stress resistance and fungal pathogenicity. [PDF]

Mol Plant Pathol, 2023
Fang Y, Jiang J, Ding H, Li X, Xie X.
europepmc   +1 more source

Molecular glues: Recent advances in cereblon substrate identification and mechanistic insights

Smart Molecules, EarlyView.
Molecular glues exert diverse core biological functions by inducing or stabilizing protein–protein interactions, extending far beyond the traditional scope of targeted protein degradation. Key breakthroughs include expanded cereblon substrate recognition, sustained G protein‐coupled receptor megacomplex signaling, and the first orthosteric molecular ...
Qingyun Guan, Xiaoyu Shi, Qian Yang, Xiangyi Jiang, Xinyong Liu, Peng Zhan   +5 more
wiley   +1 more source

Phospholipase C epsilon 1 as a therapeutic target in cardiovascular diseases. [PDF]

J Adv Res
Wang J, Gao T, Zhang D, Tang Y, Gu J.
europepmc   +1 more source

Assessment of Expression Levels and Localization Patterns of Phospholipase C zeta in Different Grades of HOST in Human Sperm. [PDF]

Int J Fertil Steril, 2023
Allahveisi A, Yousefian E.
europepmc   +1 more source

PFOA Exposure Elicits Quantitative Lipidomic Changes in the Pancreas in a Mouse Model of Pancreatic Cancer

Environmental Toxicology, EarlyView.
ABSTRACT Pancreatic cancer is the fourth leading cause of cancer deaths in the US and predicted to rise to second by 2030. Several risk factors have been identified as potential contributors to pancreatic cancer development including lifestyle factors and long‐term exposure to occupational and environmental carcinogens.
Barbara A. Hocevar, Lisa M. Kamendulis
wiley   +1 more source

Spinal TRPC3 promotes neuropathic pain and coordinates phospholipase C-induced mechanical hypersensitivity. [PDF]

Proc Natl Acad Sci U S A
Tobori S, Tamada K, Uemura N, Sawada K, Kakae M, Nagayasu K, Nakagawa T, Mori Y, Kaneko S, Shirakawa H.   +9 more
europepmc   +1 more source

Protective Effects of Bee Venom (Apis mellifera) Against Cadmium‐Induced Hepatorenal Toxicity, Oxidative Stress, and Anxiety‐Like Behavior in Rats

Environmental Toxicology, EarlyView.
ABSTRACT Cadmium (Cd) is a persistent environmental heavy metal and a major public health concern because it persists in the body for long periods and gradually accumulates in vital organs, particularly the liver, kidneys, and brain. Chronic Cd exposure promotes the excessive production of reactive oxygen species (ROS), which ultimately leads to ...
Soumaya Ghodbane, Chedli Ellijimi, Rym Elfessi, Ranya Hezzi, Khemaies Ben Rhouma, Hafedh Abdelmelek, Najet Srairi‐Abid, Mohsen Sakly, Riadh Marrouchi   +8 more
wiley   +1 more source

Mammalian PI-Phospholipase C Isozymes: Structural and Functional Insights and Roles in Health and Disease. [PDF]

Medicina (Kaunas)
Hamdi M, Al-Matwi M, Elghoul N, Al-Kuwari H, Sayed TS, Riguene E, Nomikos M.   +6 more
europepmc   +1 more source

Identification and Validation of Biomarkers in Chronic Rhinosinusitis With Nasal Polyps and Study of Their Associated Mechanisms

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Cell senescence (CS) and lipid metabolism (LM) disorders have been reported in chronic rhinosinusitis with nasal polyps (CRSwNP). However, the mechanism is still unclear. Methods Data were obtained from public databases; differential expression analysis and machine learning were performed to identify biomarkers and to understand the
Hui‐Yi Deng, Hui‐Jun Qiu, Ming‐Rui Pan, Qin‐Tai Yang   +3 more
wiley   +1 more source

The non-specific phospholipase C of common bean PvNPC4 modulates roots and nodule development. [PDF]

PLoS One
Pacheco R, Juárez-Verdayes MA, Chávez-Martínez AI, Palacios-Martínez J, Leija A, Nava N, Cárdenas L, Quinto C.   +7 more
europepmc   +1 more source